JoAnne Stubbe
JoAnne Stubbe (born June 11, 1946 in Champaign , Illinois ) is an American biochemist .
Stubbe studied chemistry at the University of Pennsylvania ( Bachelor's degree in 1968) and received his PhD in organic chemistry from the University of California, Berkeley , in 1971 . She was a post-doctoral student at Brandeis University (1975–1977).
Stubbe taught from 1972 to 1977 at Williams College and from 1977 to 1982 at the School of Medicine of Yale University . From 1983 she was a professor at the University of Wisconsin – Madison . She is Professor of Biology and Chemistry ( Novartis Professor of Chemistry ) at the Massachusetts Institute of Technology (MIT), where she has worked since 1987.
She clarified the function and structure of ribonucleotide reductases (RNR), which play a role in the conversion of nucleotides into deoxynucleotides in the replication of DNA . This also resulted in an anti-cancer drug (Gemcitabine), which is used, for example, in pancreatic cancer. They determined the structure and DNA-damaging function of the antibiotic bleomycin , which is also used as a cancer drug.
Most recently, she has been researching bacterial enzymes that can be used to make biodegradable plastics. She and her group isolated the first such enzyme (PHA synthase) and examined the polymers built up by the enzyme.
In 2010 she received the Welch Award in Chemistry . She is a member of the National Academy of Sciences , the American Academy of Arts and Sciences, and the American Philosophical Society . She received the National Medal of Science in 2008 for her research into enzymes that play an important role in the repair and replication of DNA.
She received the NAS Award in Chemical Sciences in 2008, the Kaiser Award in 2008, the Nakanishi Award in 2009, the Pfizer Award in Enzyme Chemistry in 1986 , the Cope Scholar Award in 1993, the Prelog Medal in 2009 , and the Alfred Bader Award in Bioorganic and Bioinorganic Chemistry in 1997 and in 1989 the ICI-Stuart Pharmaceutical Award for Excellence in Chemistry. In 2015 she received the Remsen Award , for 2017 she was awarded the Pearl Meister Greengard Prize , for 2020 the Priestley Medal .
Due to the number of her citations, Clarivate Analytics has been one of the favorites for a Nobel Prize in Chemistry ( Clarivate Citation Laureates ) since 2018 .
Web links
Individual evidence
- ^ Clarivate Analytics Reveals Annual Forecast of Future Nobel Prize Recipients. In: clarivate.com. Clarivate Analytics, September 20, 2018, accessed September 20, 2018 .
| personal data | |
|---|---|
| SURNAME | Stubbe, JoAnne |
| BRIEF DESCRIPTION | American biochemist |
| DATE OF BIRTH | June 11, 1946 |
| PLACE OF BIRTH | Champaign , Illinois |