Joseph R. Lakowicz

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Joseph Raymond Lakowicz (* 1948 in Philadelphia ) is an American biochemist . He is professor at the School of Medicine at the University of Maryland in Baltimore and director of the Center for Fluorescence Spectroscopy there and author of the standard work in this field, which was published in its third edition in 2006.

Life

Joseph Raymond Lakowicz, Jr. was born in Philadelphia, Pennsylvania in 1948 . He studied biology at La Salle College in Philadelphia (now La Salle University) in the late 1960s, but later switched to chemistry; B.Sc. 1970. He then studied at the University of Illinois - including with Gregorio Weber , a major pioneer in the field of fluorescence spectroscopy - where he received his doctorate in 1973. From 1973 to 1974 he was a post-doctoral student in the Department of Biochemistry at the University of Oxford in England . On his return he became an assistant professor of biochemistry at the University of Minnesota and in 1980 he moved to the University of Maryland in Baltimore, where he has been professor of biochemistry and molecular biology since 1984 . In 1988 he became director of the Center for Fluorescence Spectroscopy in the University's School of Medicine . The focus of research is fluorescence and its application in spectroscopy , microscopy and imaging processes .

Lakowicz coined the term fluorescence lifetime imaging microscopy (FLIM) and his laboratory was involved in the first publications on the experimental application of light and fluorescence quenching with time-delayed light pulses in the mid-1990s . One of the co-authors was Stefan Hell , who developed the STED microscopy based on it at the time, which he was able to realize experimentally for the first time in 1999.

In 1983 the first edition of his textbook Principles of Fluorescence Spectroscopy was published , which subsequently became the standard work in this field and was published in its third edition in 2006 (5th corrected print 2010). He is also the founder of the Journal of Fluorescence and the Journal of Biomedical Optics .

Works (selection)

  • Principles of Fluorescence Spectroscopy. (1st edition 1983, 2nd edition 1999) 3rd edition, Springer, 2006, ISBN 978-0-387-31278-1 (5th corrected print 2010).
  • Editor of: Topics in Fluorescence Spectroscopy. (Vol. 1, 1991; Vol. 12, 2007), Kluwer Academic / Springer, 1991-2007.
  • With Jian Zhang: Emerging Applications of Colloidal Noble Metals in Cancer Nanomedicine. Future Medicine, London 2012, ISBN 978-1-78084-072-7 .

Web links

Individual evidence

  1. ↑ Joseph R. Lakowicz Is May Speaker. ( Memento of March 4, 2016 in the Internet Archive ) Puget Sound Chemist: Bulletin of the Puget Sound Section of the American Chemical Society, Vol. 36, No. 5, May 1975, p. 3.
  2. ↑ a b c Kathy Kincade: Joseph R. Lakowicz. BioOptics World, May 1, 2008. Retrieved July 8, 2014.
  3. Jump up ↑ SW Hell, M. Schrader, K. Bahlmann, F. Meinecke, JR Lakowicz, I. Gryczynski: Stimulated emission on microscopic scale: Light quenching of Pyridine 2 using a Ti: sapphire laser. In: Journal of Microscopy. Vol. 180, No. 2, 1995, pp. RP1-RP2, doi: 10.1111 / j.1365-2818.1995.tb03662.x .
  4. ↑ Ignacy Gryczynski, Stefan W. Hell, Joseph R. Lakowicz: Light quenching of pyridine2 fluorescence with time-delayed pulses. In: Biophysical Chemistry. Vol. 66, No. 1, 1997, pp. 13-24, doi : 10.1016 / S0301-4622 (96) 02264-8 .
  5. ↑ Thomas A. Klar, Stefan W. Hell: Subdiffraction resolution in far-field fluorescence microscopy. In: Optics Letters. Vol. 24, No. 14, 1999, pp. 954-956, doi: 10.1364 / OL.24.000954 .
personal data
SURNAME Lakowicz, Joseph R.
ALTERNATIVE NAMES Lakowicz, Joseph Raymond (full name)
BRIEF DESCRIPTION American biochemist
DATE OF BIRTH 1948
PLACE OF BIRTH Philadelphia