Manfred Wood

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Manfred Holz (born July 25, 1938 in Ludwigshafen am Rhein , † October 22, 2014 ) was a German physicist .

Life

Manfred Holz was the son of Paul and Berta Holz, nee Mietzner, and older brother of the painter Werner Holz . He grew up in Hettenleidelheim ( Palatinate ). After attending the natural science high school in Frankenthal , he studied physics at the University of Karlsruhe , today's Karlsruhe Institute of Technology (KIT). In his diploma thesis with Günther Laukien , Holz designed and implemented a "quartz-controlled pulse program generator" for nuclear magnetic resonance devices (NMR). Holz thus built the first NMR pulse spectrometer in which all measurement times and transmitter frequencies are fully synchronized. This concept became the important device basis of modern nuclear magnetic resonance and thus also magnetic resonance tomography devices.

In the Bruker company founded by Laukien , Holz - in a group, together with his colleague Bertold Knüttel - developed the world's first commercially available nuclear magnetic resonance pulse spectrometer .

From 1970, Holz worked at the Institute for Physical Chemistry at the University of Karlsruhe. There, Manfred Holz received his doctorate from Hermann Gerhard Hertz with a dissertation on the application of NMR relaxation to questions of hydrophobic effects . Holz then worked as Academic Director with Hertz in research and teaching. After Hertz retired in October 1990, Holz took over the management of the NMR laboratory at the Institute for Physical Chemistry at the University of Karlsruhe. He held this management position until 2001. A project within the research group, which was funded by the German Research Foundation, was about the introduction of NMR methods, such as MRT, into engineering .

Manfred Holz had lived in Durmersheim in Baden since 1966 . From 2005 to 2014 he was a volunteer Wikipedia author.

Research areas

Holz was mainly concerned with the development of equipment and methods as well as the application of nuclear magnetic resonance ( NMR spectroscopy ), which is also the basis of magnetic resonance tomography . The investigation of the microstructure, the microdynamics and dynamic isotope effects of liquids and electrolyte solutions represented one of the main areas of application. The precise measurement of self-diffusion coefficients of liquids, such as e.g. B. of water , using field gradient NMR was also an important part of his research. He has also done methodological development work in the field of field gradient NMR and established the field of electrophoretic NMR (ENMR). B. the migration of ions in porous systems can be measured without contact. He devoted a large part of his research to the phenomena of hydrophobic effects, which are important in the life sciences .

The results of his scientific work are presented in more than one hundred publications.

Web links

Individual evidence

  1. Manfred Holz: Nuclear magnetic pulse spectrometry with quartz-stabilized measuring times. Diploma thesis, University of Karlsruhe 1965.
  2. A. Geiger, M. Holz: Automation and Control in high power pulsed NMR. In: J. Phys. E: Sci.Instrum. 13, 1980, pp. 697-707.
  3. Manfred Holz, Bertold Knüttel: Pulsed nuclear magnetic resonance. A physical method with a variety of uses. In: Phys. Blätter , 38,1982, pp. 368-374.
  4. Manfred Holz: Electrolytes. In: Encyclopedia of Nuclear Magnetic Resonance. DM Grant and RK Harris Eds., J. Wiley and Sons, 1996, Vol. 3, pp. 1857-1864.
  5. M. Holz, SR Heil, A. Sacco: Temperature-dependent self-diffusion coefficients of water and six selected molecular liquids for calibration in accurate 1H NMR PFG Measurements. In: Phys. Chem. Chem. Phys. 2, 2000, pp. 4740-4742, doi : 10.1039 / b005319h .
  6. Manfred Holz: Field-Assisted Diffusion Studied by Electrophoretic NMR. In: Paul Heitjans , Jörg Kärger (Eds.): Diffusion in Condensed Matter. Methods, Materials, Models. Greatly enlarged and completely revised edition. Springer, Berlin a. a. 2005, ISBN 3-540-20043-6 , pp. 717-742.
  7. Manfred Holz (1995): Nuclear Magnetic Relaxation as a Selective Probe of Solute - Solvent and Solute - Solute Interactions in Multi-component Mixtures. In: J. Mol. Liquids , 67, 175-191.
  8. M. Holz, M. Mayele Influence of Additives on Hydrophobic Association in Polynary Aqueous Mixtures In: DFG Research Report. Thermodynamic Properties of Complex Fluid Mixtures Wiley-VCH 2004, pp. 150-183, ISBN 3-527-27770-6 .