Methenolone

Structural formula
General
Non-proprietary name	Methenolone
other names	( 5α , 17β ) -17-Hydroxy-1-methylandrost-1-en-3-one
Molecular formula	C 20 H 30 O 2
External identifiers / databases
EC number	205-812-0
ECHA InfoCard	100.005.285
PubChem	3037705
ChemSpider	2301378
Wikidata	Q905078
Drug information
ATC code	A14 AA04
Drug class	Anabolic steroid
properties
Molar mass	302.45 g · mol -1
Melting point	149.5–152 ° C (methenolone) ; 138-139 ° C (methenolone acetate) ;
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
H and P phrases	H: 302-351-360-362
	P: ?
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Methenolone , also called metenolone , is an organic chemical compound from the group of steroids . As a medicinal substance Primobolan ^® , it shows a low androgenic , but strong anabolic effect.

Methenelon is either injected intramuscularly as methenolone enanthate ( Primobolan Depot ) or taken orally as methenolone acetate ( Primobolan S ). The steroid is quickly and completely absorbed after oral intake; after about 3.5 hours, 90% are metabolized to conjugates . The plasma half-life is about one day. Half of it is eliminated in the urine and half in the stool. The esters methenolone acetate and methenolone enanthate are more effective because they - depending on the tissue - first have to be converted into methenolone and the corresponding acid. The androgenic effect corresponds functionally to that of dihydrotestosterone ( androstanolone ).

Among the side effects include prostate growth , scalp hair loss, hair growth on the body, acne and masculinization in women through clitoral growth , beard growth and voice deepening.

Primobolan was manufactured by Schering AG in Germany and Mexico and is now manufactured by Bayer AG . Its use was widespread in bodybuilding circles in the 1970s .

Web links

Entry on Methenolone at Vetpharm, accessed August 4, 2012.

Individual evidence

↑ ^a ^b C. R. Ganellin, David J. Triggle: Dictionary of pharmacological agents, Volume 2: H-Z. CRC Press, 1996, ISBN 978-0-412-46630-4 , p. 1293.
↑ Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of Metenolone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), which was accessed on April 3, 2020, is reproduced from a self-classification by the distributor .
↑ ^a ^b F. v. Bruchhausen, S. Ebel, AW Frahm, E. Hackenthal: Hagers Handbook of Pharmaceutical Practice. Volume 8. Substances E-O. 5th edition, Springer, 1995, ISBN 978-3-540-52688-9 , pp. 907-908.
↑ Bernhard Kleine, Winfried Rossmanith: Hormones and hormone system: an endocrinology for bioscientists. Springer, 2007, ISBN 978-3-540-37702-3 , p. 229.
↑ Steve Theunissen: Arnold & Steroids: Truth Revealed ( Memento December 7, 2003 in the Internet Archive ), 2002.

[dictpa-1] C. R. Ganellin, David J. Triggle: Dictionary of pharmacological agents, Volume 2: H-Z. CRC Press, 1996, ISBN 978-0-412-46630-4 , p. 1293.

[2] Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of Metenolone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), which was accessed on April 3, 2020, is reproduced from a self-classification by the distributor .

[hager-3] F. v. Bruchhausen, S. Ebel, AW Frahm, E. Hackenthal: Hagers Handbook of Pharmaceutical Practice. Volume 8. Substances E-O. 5th edition, Springer, 1995, ISBN 978-3-540-52688-9 , pp. 907-908.

[4] Bernhard Kleine, Winfried Rossmanith: Hormones and hormone system: an endocrinology for bioscientists. Springer, 2007, ISBN 978-3-540-37702-3 , p. 229.

[ST-5] Steve Theunissen: Arnold & Steroids: Truth Revealed ( Memento December 7, 2003 in the Internet Archive ), 2002.