Michael G. Rosenfeld

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Michael Geoffrey "Geof (f)" Rosenfeld (* 1944 in Aberdeen , Maryland ) is an American biochemist and molecular biologist at the University of California, San Diego (UCSD).

Rosenfeld earned a bachelor's degree from Johns Hopkins University and an MD from the University of Rochester with a medical degree. He worked as an assistant doctor at Washington University in St. Louis and as a research assistant to Bert O'Malley and Ira Pastan at the National Institutes of Health (NIH). He was briefly a doctor at Barnes Hospital before working as a postdoctoral fellow with Leonard Garren at UCSD. Rosenfeld holds a professorship at UCSD and is adjunct professor at the Scripps Research Institute and the Salk Institute . Since 1985 Rosenfeld has also been doing research for the Howard Hughes Medical Institute .

Rosenfeld deals with the molecular (especially hormonal ) mechanisms of the control of transcription , insofar as they underlie the phenotypic development of cells ( differentiation ). He is particularly interested in these processes in the brain , in endocrine glands (and their combination, the neuroendocrine system) and in the development of cancer . Often nuclear receptors , members of the POU family (which was discovered by Rosenfeld) and other transcription factors are involved.

Michael G. Rosenfeld became a member of the American Academy of Arts and Sciences in 1991 and of the National Academy of Sciences in 1994 . In 1999 he received (together with Ronald M. Evans ) the Fred Conrad Koch Award of the Endocrine Society and in 2012 (together with David M. Livingston and Joan Massagué ) the Pasarow Award for cancer research.

literature

  • Vicki Glaser: An Interview with Michael G. Rosenfeld, MD, University of California, San Diego . In: ASSAY and Drug Development Technologies . tape 4 , no. 3 , June 2006, p. 235 , doi : 10.1089 / adt.2006.4.235 , PMID 16834529 .

Web links

Individual evidence

  1. Michael G. Rosenfeld, MD. In: hhmi.org. April 18, 2016, accessed February 3, 2018 .
  2. Book of Members 1780 – present, Chapter R. (PDF; 508 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved February 3, 2018 .
  3. Michael Rosenfeld. In: nasonline.org. Retrieved February 3, 2018 .
  4. Gordon N. Gill: Citation for the 1999 Fred Conrad Koch Award of The Endocrine Society to Dr. Ronald M. Evans and Dr. Michael G. Rosenfeld. In: Endocrine Reviews. 20, 1999, p. 585, doi : 10.1210 / edrv.20.4.7009 .
  5. ^ Professor Peter Ratcliffe receives Pasarow Award in Cardiovascular Disease - Nuffield Department of Medicine. In: ndm.ox.ac.uk. Retrieved February 3, 2018 .