N 4 -methylcytosine

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Structural formula
Structure of N4-methylcytosine
General
Surname N 4 -methylcytosine
other names

4-methylamino-pyrimidin-2-one

Molecular formula C 5 H 7 N 3 O
External identifiers / databases
CAS number 6220-47-9
PubChem 122004
ChemSpider 108831
Wikidata Q15632688
properties
Molar mass 125.13 g mol −1
Physical state

firmly

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

N 4 -Methylcytosine is a heterocyclic organic compound with a pyrimidine backbone. It is a derivative of the nucleobase cytosine , whichis methylated at the amino group . It occurs as a component of the nucleoside N 4 -methylcytidine  (m 4 C) in RNA , and also in bacterial DNA .

The dimethylated variant is N 4 , N 4 -dimethylcytosine .

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Melanie Ehrlich, Geoffrey G. Wilson, Kenneth C. Kuo, Charles W. Gehrke: “ N 4 -Methylcytosine as a Minor Base in Bacterial DNA”, J Bacteriol , 1987 , 169  (3), pp. 939-943 ( PMC 211883 (free full text); PMID 3029036 ).
  3. ↑ Melanie Ehrlich, Miguel A. Gama-Sosa, Laura H. Carreira, Lars G. Ljungdahl, Kenneth C. Kuo, Charles W. Gehrke: "DNA methylation in thermophilic bacteria: N 4 -methylcytosine, 5-methylcytosine, and N 6 -methyladenine ", Nucleic Acids Research , 1985 , 13  (4), pp. 1399-1412 ( doi : 10.1093 / nar / 13.4.1399 ; PMC 341080 (free full text); PMID 4000939 ).