Norbolethone

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Structural formula
Structure of norbolethone
General
Non-proprietary name Norboletone
other names

13 β- ethyl-17 β -hydroxy-18,19-dinor-17 α -pregn-4-en-3-one

Molecular formula C 21 H 32 O 2
External identifiers / databases
CAS number
  • 797-58-0
  • 1235-15-0
PubChem 66255
ChemSpider 59638
Wikidata Q410981
properties
Molar mass 316.48 g mol −1
Physical state

firmly

Melting point

170 ° C

safety instructions
GHS hazard labeling
no classification available
Toxicological data

> 5010 mg kg −1 ( LD 50mouseoral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Norbolethone , also norboletone ( INN ), is an anabolic steroid that was first synthesized in the 1960s in the Wyeth Laboratories in Philadelphia , but never reached market readiness .

Since norbolethone was relatively unknown for a long time and never commercially available, the doping tests carried out in competitive sports were not tested for the presence of the substance. The use of the strongly anabolic substance in competitive sports therefore offered opportunities to increase performance for a long time without attracting attention in doping tests. Don Catlin , director of the Olympic Analytical Laboratory in Los Angeles at UCLA , found norbolethone in a doping test carried out by track cyclist Tammy Thomas in 2002 after he was unable to find any illegal substances in a first attempt despite abnormal blood counts. It is believed that norbolethone is now made in laboratories in China or Europe .

literature

  • Catlin, DH et al. (2002): Detection of norbolethone, an anabolic steroid never marketed, in athletes' urine. In: Rapid. Commun. Mass. Spectrom. Vol. 16, pp. 1273-1275. PMID 12112254

Individual evidence

  1. Hiraga, K .: Syntheses of Racemic and Optically Active 13β-Ethylgonanes in Chem. Pharm. Bull. 13 (1965) 1289-1294, doi : 10.1248 / cpb.13.1289 , pdf .
  2. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  3. Entry on norbolethone in the ChemIDplus database of the United States National Library of Medicine (NLM) .

Web links