The members of the Paramyxovirinae were grouped together in addition to their phylogenetic proximity and distinguished from the second subfamily Pneumovirinae on the basis of their envelope proteins . While the Paramyxovirinae had either surface proteins with a hemagglutinin and / or neuraminidase activity, the envelope proteins of the Pneumovirinae did not show any of these properties.
The genome of the Paramyxovirinae had 6 or 7 open reading frames and thus 2 or 3 fewer than the Pneumovirinae . In contrast to these, the number of nucleotides in Paramyxovirinae was always divisible by 6 ( “rule of six” ), which is apparently based on a very regular packaging mechanism of the genome in the helical capsid .
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RA Lamb, PL Collins et al .: Subfamily Paramyxovirinae . In: CM Fauquet, MA Mayo et al .: Eighth Report of the International Committee on Taxonomy of Viruses . London, San Diego, 2005 p. 659 ISBN 0-12-249951-4
S. Mordrow, D. Falke, U. Truyen: Molecular Virology , Heidelberg Berlin, 2nd edition 2003 ISBN 3-8274-1086-X
