Paul Rösch

from Wikipedia, the free encyclopedia

Paul Rösch (born July 13, 1952 in Heidelberg ) is a German biophysicist , university professor and company founder and CEO.

Paul Rösch

Life

Paul Rösch studied physics at the University of Karlsruhe (TH) and the University of Heidelberg . He passed the diploma examination in 1976. Just two years later received his doctorate he at the same university for Doctor of Science (Dr. rer. Nat.); He carried out his doctoral thesis at the Max Planck Institute for Medical Research in Heidelberg with Karl Hermann Hauser. He then worked as a postdoctoral fellow at the University of Pennsylvania School of Medicine with Mildred Cohn and Britton Chance on phosphotransferases. In 1979 he returned to the Max Planck Institute for Medical Research in Heidelberg in the Biophysics department headed by Ken Holmes . He received his teaching license in biophysics in 1989 at the University of Heidelberg. From 1990 to 2018 Paul Rösch held the chair of biopolymers at the Faculty of Biology, Chemistry and Geosciences at the University of Bayreuth and director of the research center for bio-macromolecules there. He was vice spokesman of the Collaborative Research Center “Lymphoproliferation and Viral Immunodeficiency”, which expired in 2007, from 2004 to 2008 he was vice spokesman in the DFG review committee “Fundamentals of Biology and Medicine” and spokesman for the graduate school in the Bavarian elite network “Lead Structures of Cell Function”, which ended in 2012 .

In 2010 he founded ALNuMed GmbH together with Stephan Schwarzinger. Since 2015 he has been CEO of the company.

Services

Paul Rösch deals with the spatial structure of biomolecules in solution, the technique he mainly uses is NMR spectroscopy . Early scientific contributions included work on the elucidation of the reaction mechanism of phosphotransferases, for example the bacterial phosphorous carrier protein HPr and the adenylate kinase . He later devoted himself to elucidating the structure of the transactivator protein from HIV and the peptide Aß in Alzheimer's disease . This was followed by contributions on the structural basis of the regulation of transcription in bacteria, the elucidation of the structure of allergens and studies on the structure of peptide hormones . Under his leadership, the Joint Science Conference approved the world's second 1 GHz NMR spectrometer as a research building for the North Bavarian NMR Center in 2011 . He is a member of the Editorial Board of the Journal of Bioequivalence & Bioavailability , Trends in Immunotherapy and Scientifica . Rösch is also a member of the German Physical Society , the German Society for Biophysics and the Society of German Natural Scientists and Doctors . Rösch is the recipient of the "Ludwig Schaefer Award for Excellence in Human Physiology Research" 2015 from Columbia University in New York.

Fonts

  • Burmann BM, Knauer SH, Sevostyanova A, Schweimer K, Mooney RM, Landick R, Artsimovitch I, Rösch P. An α Helix to β Barrel Domain Switch Transforms the Transcription Factor RfaH into a Translation Factor. Cell . 2012 150: 291-303.
  • Schweimer K, Prasch S, Sujatha PS, Bubunenko M, Gottesman ME, Rösch P. NusA interaction with the α subunit of E. coli RNA polymerase is via the UP element site and releases autoinhibition structure . 2011 19: 945-54.
  • Burmann BM, Schweimer K, Luo X, Wahl MC, Stitt BL, Gottesman ME, Rösch P. A NusE: NusG complex links transcription and translation. Science . 2010 328: 501-4.
  • Sticht H, Bayer P, Willbold D, Dames S, Hilbich C, Beyreuther K, Frank RW, Rösch P. Structure of amyloid A4- (1-40) -peptides of Alzheimer's disease. Eur J Biochem . 1995 233: 293-8.
  • Willbold D, Rosin-Arbesfeld R, Sticht H, Frank R, Rösch P. Structure of the equine infectious anemia virus Tat protein. Science . 1994 264: 1584-7.

Web links

Individual evidence

  1. ↑ Chair of Biopolymers, former employees. Retrieved April 20, 2019 .
  2. ^ CV Paul Rösch. University of Bayreuth;
  3. ↑ SFB 466: Lymphoproliferation and Viral Immunodeficiency. DFG, accessed on April 20, 2019 .
  4. ^ Lead Structures of Cell Function. Elitenetzwerk Bayern, accessed on April 20, 2019 .
  5. ↑ About ALNuMed. Retrieved April 20, 2019 .
  6. ↑ The world's second high-field NMR spectrometer is to come to the University of Bayreuth. (pdf) uni-bayreuth.de, July 12, 2011, accessed on April 20, 2019 .
  7. ↑ Four New Schaefer Scholars Pursue Human Physiology Research. Columbia University, February 13, 2015, accessed April 20, 2019 .
personal data
SURNAME Rösch, Paul
BRIEF DESCRIPTION German biophysicist and university professor
DATE OF BIRTH July 13, 1952
PLACE OF BIRTH Heidelberg