Phenol blue

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Structural formula
Structural formula of phenolic blue
General
Surname Phenol blue
other names
  • N , N '-Dimethylindoanilin
  • 4- (4-Dimethylaminophenyl) iminocyclohexa-2,5-dien-1-one ( IUPAC )
  • Azuline
Molecular formula C 14 H 14 N 2 O
Brief description

hygroscopic dark brown to black solid

External identifiers / databases
CAS number 2150-58-5
EC number 218-434-6
ECHA InfoCard 100,016,759
PubChem 75078
ChemSpider 67630
Wikidata Q2085508
properties
Molar mass 226.28 g mol −1
Physical state

firmly

density

1.02 g cm −3 (72.4 ° C)

Melting point

133-134 ° C

pK s value
  • pK s 1 : 5.96 (30 ° C)
  • pK s 2 : 9.89 (30 ° C)
solubility

soluble in water

safety instructions
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-319-335
P: 302 + 352-305 + 351 + 338
Toxicological data

80 mg kg −1 ( LD 50 ,  mouse ,  ip )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Phenol blue is a dark brown to black chemical compound that dissolves in water with a blue color. The dye is structurally a nitrogen analogue to quinones .

Properties, use and toxicology

Phenol blue is a hygroscopic , dark brown to black, water-soluble solid. It is used as a redox indicator. In mice, phenol blue with an LD 50 value of 80 mg / kg body weight was found to be toxic after intraperitoneal administration.

Individual evidence

  1. ↑ a b c d e Alan Townshend: Dictionary of analytical reagents. CRC Press, 1993, ISBN 0-412-35150-1 , p. 773.
  2. ^ Carl L. Yaws: Thermophysical Properties of Chemicals and Hydrocarbons. William Andrew, 2008, ISBN 978-0-8155-1596-8 , p. 269.
  3. ↑ a b c data sheet N, N-dimethylindoaniline from Sigma-Aldrich , accessed on December 23, 2019 ( PDF ).
  4. ↑ a b Entry on phenol blue in the ChemIDplus database of the United States National Library of Medicine (NLM) .
  5. ↑ Ernest M. Hodnett, Gopalakrishnan Prakash, Jafargholi Amirmoazzami: "Nitrogen analogs of 1,4-benzoquinones. Activities against the ascitic sarcoma 180 of mice", in: Journal of Medicinal Chemistry , 1978 , 21 (1) , p. 11– 16; doi : 10.1021 / jm00199a003 .

See also