Putrescine

Structural formula
General
Surname	Putrescine
other names	Butane-1,4-diamine; 1,4-diaminobutane; Tetramethylene diamine;
Molecular formula	C 4 H 12 N 2
Brief description	colorless crystalline solid with an amine-like odor
External identifiers / databases
EC number	203-782-3
ECHA InfoCard	100.003.440
PubChem	1045
ChemSpider	13837702
DrugBank	DB01917
Wikidata	Q410190
properties
Molar mass	88.15 g mol −1
Physical state	firmly
density	0.88 g cm −3
Melting point	25-27 ° C
boiling point	158 ° C
solubility	soluble in water (40 g l −1 at 20 ° C)
safety instructions
H and P phrases	H: 226-302-311-314-330
	P: 210-280-303 + 361 + 353-304 + 340 + 310-305 + 351 + 338
Toxicological data	463 mg kg −1 ( LD 50 , rat , oral ) ; 1580 mg kg −1 ( LD 50 , rabbit , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Putrescine (from Latin : putrere "rot, fester") is the common name for butane-1,4-diamine , a diamine of n- butane .

Occurrence

Putrescine is a case of meat rotting, but also in living organisms from ornithine by decarboxylation arising biogenic amine . The enzyme ornithine decarboxylase is responsible for this decomposition . Putrescine is found in fresh meat and its amount increases with the length of storage. In food chemistry , the putrescine content is an indication of the freshness of meat.

As a putrefaction base, it is part of the ptomaine (so-called corpse poison) and thus also contributes to the odor of decay .

use

1,4-Diaminobutane is a starting component for macromolecular substances as well as for the production of pharmaceuticals and pesticides.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on tetramethylenediamine in the GESTIS substance database of the IFA , accessed on April 22, 2020(JavaScript required) .
↑ Data sheet 1,4-diaminobutane from Sigma-Aldrich , accessed on January 19, 2020 ( PDF ).
↑ Data sheet 1,4-diaminobutane (PDF) from Merck , accessed on January 19, 2020.
↑ Wolfgang Legrum: Fragrances, between stench and fragrance , Vieweg + Teubner Verlag (2011), ISBN 978-3-8348-1245-2 , p. 65.

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h Entry on tetramethylenediamine in the GESTIS substance database of the IFA , accessed on April 22, 2020(JavaScript required) .

[2] Data sheet 1,4-diaminobutane from Sigma-Aldrich , accessed on January 19, 2020 ( PDF ).

[3] Data sheet 1,4-diaminobutane (PDF) from Merck , accessed on January 19, 2020.

[Legrum-4] Wolfgang Legrum: Fragrances, between stench and fragrance , Vieweg + Teubner Verlag (2011), ISBN 978-3-8348-1245-2 , p. 65.