Schizosaccharomyces pombe

Schizosaccharomyces pombe
	Schizosaccharomyces pombe
Systematics
Subdivision :	Taphrinomycotina
Class :	Schizosaccharomycetes
Order :	Schizosaccharomycetales
Family :	Schizosaccharomycetaceae
Genre :	Fission Yeast ( Schizosaccharomyces )
Type :	Schizosaccharomyces pombe
Scientific name
	Schizosaccharomyces pombe
	Lindner

Schizosaccharomyces pombe is a fission yeast , i. H. a yeast that does notmultiplyby sprouting ( budding ) but by dividing the cell into two halves ("splitting"). It is a rod-shaped unicellular eukaryote that isoften used as a model organism in molecular and cell biology .

history

Paul Lindner isolated this fission yeast from East African millet beer in 1893 at the Institute for Fermentation Industry . The name S. pombe comes from the Swahili word for beer ( pombe ).

As a model organism in cell biology, it was introduced by Murdoch Mitchison in the 1950s. The British biochemist Paul Nurse received the Nobel Prize in Physiology or Medicine in 2001 together with Leland H. Hartwell and Tim Hunt for his work on cell cycle regulation in fission yeast .

The genome - the DNA sequence of S. pombe was published of 2002.

In 2006 Akihisa Matsuyama and colleagues published the subcellular localization of all proteins.

variants

About 160 natural strains of Schizosaccharomyces pombe have been identified, originating from Europe, Asia and America, among others. The majority of these variants were found on fruits such as apples and grapes or in alcoholic beverages such as the Brazilian cachaça . Schizosaccharomyces pombe is also found in fermented kombucha tea. It is not known whether the yeast plays a key role in fermentation or merely accompanies more active microorganisms. Schizosaccharomyces yeasts have not yet been extensively studied.

Comparison with baker's yeast , a budding yeast

Stages of division of Schizosaccharomyces pombe viewed in brightfield and darkfield

S. cerevisiae has ~ 5600 open reading frames , Sch. pombe has 5054
S. cerevisiae has 16 chromosomes , Sch. pombe has 3
S. cerevisiae is usually diploid , while Sch. pombe normally haploid is
S. cerevisiae is mainly in the G ₁ phase , while Sch. pombe is mainly in the G ₂ phase.

literature

Richard Egel: The Molecular Biology of Schizosaccharomyces pombe - Genetics, Genomics and Beyond. Springer, 2004, ISBN 978-3-540-00693-0 .

Individual evidence

↑ Article by the Botanical Institute of the University of Bonn ( Memento from June 11, 2007 in the Internet Archive )
↑ V. Wood et al .: The genome sequence of Schizosaccharomyces pombe . In: Nature . tape 415 , no. 6874 , February 21, 2002, ISSN 0028-0836 , p. 871-880 , doi : 10.1038 / nature724 .
↑ Akihisa Matsuyama et al .: ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe . In: Nature Biotechnology . tape 24 , no. 7 , July 1, 2006, p. 841-847 , doi : 10.1038 / nbt1222 .
↑ Ai Leng Teoh: Yeast ecology of Kombucha fermentation . In: International Journal of Food Microbiology . 95, No. 2, September 2004, pp. 119-26. doi : 10.1016 / j.ijfoodmicro.2003.12.020 . PMID 15282124 .
↑ ^a ^b PomBase statistics

[1] Article by the Botanical Institute of the University of Bonn ( Memento from June 11, 2007 in the Internet Archive )

[2] V. Wood et al .: The genome sequence of Schizosaccharomyces pombe . In: Nature . tape 415 , no. 6874 , February 21, 2002, ISSN 0028-0836 , p. 871-880 , doi : 10.1038 / nature724 .

[3] Akihisa Matsuyama et al .: ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe . In: Nature Biotechnology . tape 24 , no. 7 , July 1, 2006, p. 841-847 , doi : 10.1038 / nbt1222 .

[4] Ai Leng Teoh: Yeast ecology of Kombucha fermentation . In: International Journal of Food Microbiology . 95, No. 2, September 2004, pp. 119-26. doi : 10.1016 / j.ijfoodmicro.2003.12.020 . PMID 15282124 .

[PomBase-5] PomBase statistics