St. Louis encephalitis

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Classification according to ICD-10
A83.3 St. Louis encephalitis
ICD-10 online (WHO version 2019)

The Saint Louis encephalitis , including encephalitis St. Louis , is one of the most common by arboviruses triggered disease in North America and is also of travel medical importance.

Pathogen

St. Louis Encephalitis Virus
St. Louis Encephalitis (SLE) virus EM PHIL 1871 lores.JPG

SLE virus in the salivary gland of a mosquito

Systematics
Classification : Viruses
Area : Riboviria
Empire : Orthornavirae
Phylum : Kitrinoviricota
Class : Flasuviricetes
Order : Amarillovirales
Family : Flaviviridae
Genre : Flavivirus
Type : St. Louis Encephalitis Virus
Taxonomic characteristics
Genome : (+) ssRNA linear
Baltimore : Group 4
Symmetry : icosahedral
Cover : available
Scientific name
Saint Louis encephalitis virus
Short name
SLEV
Left

St. Louis encephalitis is caused by viruses of the species St. Louis encephalitis virus ( scientifically Saint Louis encephalitis virus , SLEV). The enveloped, single-stranded RNA virus with positive polarity belongs to the genus Flavivirus , family Flaviviridae .

transmission

The virus is transmitted by mosquitoes (genus Culex and species Stegomyia albopicta ). During a blood meal on an infected animal, the mosquitoes ingest the virus and can later transmit it to humans or animals by biting again. Birds and bats are animal reservoirs . Humans are just a false host , there is no human-to-human transmission.

Occurrence

Endemic areas in the USA are the Ohio-Mississippi Basin , Texas , Florida , Colorado and California , as well as Jamaica . The virus is also endemic in Canada , Central and South America , but has probably not triggered any epidemics there . Transmission takes place most frequently between July and October, depending on the mosquito's life cycle.

clinic

In most cases the disease is inapparent and has no consequences. However, after an incubation period of a few days, 1–5% of those infected suddenly develop a high fever , accompanied by headache and body aches, photophobia and dizziness . This can lead to neurological symptoms , especially in older people : meningitis or encephalitis . The recovery can take weeks and months, are also possible permanent neurological deficits such. B. Gait and speech disorders. The lethality can be up to 20%.

therapy

There is no specific therapy or vaccination . Protection against mosquito bites is therefore recommended for travelers to endemic areas: repellants , mosquito nets , light-colored, long clothing, avoiding outside stays during and after dusk.

Web links

Individual evidence

  1. ICTV Master Species List 2018b.v2 . MSL # 34, March 2019
  2. a b c d ICTV: ICTV Taxonomy history: Yellow fever virus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)