Sulbentine

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Structural formula
Structural formula of sulbentine
General
Non-proprietary name Sulbentine
other names
  • Dibenzthion
  • Dibenzothione
  • 3,5-dibenzyl-1,3,5-thiadiazinan-2-thione ( IUPAC )
Molecular formula C 17 H 18 N 2 S 2
External identifiers / databases
CAS number 350-12-9
EC number 206-497-2
ECHA InfoCard 100.005.907
PubChem 67686
Wikidata Q2364327
Drug information
ATC code

D01 AE09

properties
Molar mass 314.48 g · mol -1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
09 - Dangerous for the environment 07 - Warning

Caution

H and P phrases H: 302-315-319-335-400
P: ?
Toxicological data

1100 mg kg −1 ( LD 50mouseoral )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Sulbentine (Dibenzthion) is an antifungal agent for topical (local) use . It is effective against dermatophytes . Together with the similarly acting monobenzthione , it belongs to the group of thiadiazines .

Trade names

Fungiplex (except trade) u. a.

See also

literature

  • L. von Krempl-Lamprecht: Studies on the antimycotic effectiveness of the thiadiazines dibenzthione and monobenzthione . In: Mycoses 9/1, 2010, pp. 11-22.
  • (without author): Dibenzthione (Fungiplex) in experiment, clinics and general practice (in German). In: Mykosen 11/1, 1968, pp. 97-100. PMID 4920270 .

Individual evidence

  1. Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of Sulbentine in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), which was accessed on July 12, 2020, is reproduced from a self-classification by the distributor .
  2. ^ Axel Kleemann , Jürgen Engel, Bernd Kutscher and Dieter Reichert: Pharmaceutical Substances , 4th edition (2000), p. 1915, 2 volumes published by Thieme-Verlag Stuttgart, ISBN 978-1-58890-031-9 ; online since 2003 with biannual additions and updates.