Thorsten Walles

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Thorsten Walles (born June 28, 1972 in Lingen ) is a German specialist in thoracic surgery at the Magdeburg University Hospital . He is known for his work in the field of trachea surgery as well as his research on lung cancer early diagnosis.

Thorsten Walles

Life

Walles studied human medicine at the Hannover Medical School from 1993 to 2000 . From 1997 to 1998 he was doing a research stay as part of his doctorate at Johns Hopkins University , Baltimore, USA. He received his doctorate in 2000 from the Hannover Medical School on the proportion of poly (ADP-ribose) polymerase (PARP) activity in post-ischemic reperfusion damage in the heart . From 2000 to 2008 he completed his specialist training in thoracic surgery at various clinics and in 2008 received the additional title of European specialist in thoracic surgery (Fellow of the European Board of Thoracic and Cardiovascular Surgeons). From 2005 to 2012 Walles was a visiting scientist at the Fraunhofer Institute for Interfacial Engineering and Biotechnology in Stuttgart. He received his habilitation in 2009 with the topic of developing a bioartificial replacement tissue for tracheal surgery at the Eberhard Karls University of Tübingen . In 2010 he was appointed senior physician at the Schillerhöhe Clinic in Stuttgart. In 2012 Walles was appointed university professor (W2) for thoracic surgery at the Medical Faculty of the Julius Maximilians University of Würzburg . From 2012 to 2016 he was head of the Thoracic Surgery Section at the University Hospital Würzburg . He has been Head of Thoracic Surgery at Magdeburg University Hospital since 2017 .

Thorsten Walles is married to the biologist Heike Walles .

Scientific contribution

When he started working as a surgeon, Walles began researching regenerative medicine and tissue engineering . After moving to thoracic surgery, he focused on the manufacture of a bioartificial trachea transplant using tissue engineering. The work on the bioartificial trachea transplant resulted in the world's first clinical application of tissue engineering methods to reconstruct the airways. During the comprehensive scientific follow-up of these first artificial tissues transplanted into a human, his working group was able to show a post-transplant maturation process in them. The fact that the translation of tissue engineering processes in clinical practice represents an internationally innovative treatment method resulted in a scientific examination of the regulatory framework for regenerative medicine in Germany and Europe. As a specialist in the treatment of lung cancer, Walles was also able to show that the tumor disease can be detected in the breath of patients. The aim of his research work is the development of measuring methods for the early diagnosis of lung cancer.

honors and awards

  • 1998 Scholarship from the Carl Duisberg Foundation and the German Academic Exchange Service (DAAD) for the Biomedical Exchange Program.
  • 2002 Young Investigator Award from the World Heart Federation
  • 2003 Young Researcher Award from the European Society of Artificial Organs (ESAO)
  • 2003 Young Investigator Award from the European Association for Cardio-Thoracic Surgery (EACTS)
  • 2010 Von Langenbeck Prize of the German Society for Surgery (DGCH)

Memberships in scientific societies

Walles is also on the editorial board of the specialist journals Expert Review of Medical Devices and Chirurgische Allgemeine Zeitung .

literature

  • Bernhard Albrecht: Patient of my life: From doctors who dare to do everything. Droemer-Knaur, 2013, ISBN 978-3-426-27594-8 .

Publications

Web links

Individual evidence

  1. ↑ a b Prof. Dr. med. Thorsten Walles strengthens the University Hospital Würzburg and the Comprehensive Cancer Center Mainfranken. ( Memento from May 11, 2016 in the Internet Archive )
  2. ↑ a b T. Walles, H. Gorler, C. Puschmann, H. Mertsching: Functional neointima characterization of vascular prostheses in human. In: Ann Thorac Surg. 77, 2004, pp. 864-868.
  3. ↑ T. Walles, B. Giere, M. Hofmann, J. Schanz, F. Hofmann, H. Mertsching, P. Macchiarini: Experimental generation of a tissue-engineered functional and vascularized trachea. In: J Thorac Cardiovasc Surg. 128, 2004, pp. 900-906.
  4. ^ T. Walles: Tracheobronchial bio-engineering: biotechnology fulfilling unmet medical needs. In: Adv Drug Deliv Rev. 63, 2011, pp. 367-374.
  5. ↑ P. Macchiarini, T. Walles, C. Biancosino, H. Mertsching: First human transplantation of a bioengineered airway tissue. In: J Thorac Cardiovasc Surg. 128, 2004, pp. 638-641.
  6. ^ T. Walles, C. Biancosino, P. Zardo, P. Macchiarini, J. Gottlieb, H. Mertsching: Tissue remodelling in a bioartificial fibromuscular patch following transplantation in a human. In: transplant. 80, 2005, pp. 284-285.
  7. ↑ M. Steinke, I. Dally, G. Friedel, H. Walles, T. Walles: Host-integration of a tissue-engineered airway patch: 2-year follow-up in a single patient. In: Tissue Eng Part A. 21, 2015, pp. 573-579.
  8. ↑ H. Mertsching, T. Walles: Europe's advanced therapy medicinal products: Chances and challenges. In: Exp Rev Med Dev. 6, 2009, pp. 109-110.
  9. ↑ MM Altmayer, T. Walles: Bioartificial Transplants in Reconstructive Surgery: Translation and Economic Advantages in Patient Care. In: Regenerat Med. 1, 2009, pp. 23-25.
  10. ↑ U. Brucklacher, T. Walles: The new tissue law and its significance for surgical therapy and research. In: CHAZ. 11, 2010, pp. 561-565.
  11. ↑ U. Brucklacher, T. Walles: National and European framework conditions for tissue engineering. In: Pharma Law. 32, 2010, pp. 581-585.
  12. ↑ M. Hampel, I. Dally, T. Walles, V. Steger, S. Veit, T. Kyriss, G. Friedel: Impact of neo-adjuvant radiochemotherapy on bronchial tissue viability. In: Eur J Cardiothorac Surg. 37, 2010, pp. 461-466.
  13. ↑ R. Ehmann, E. Boedeker, U. Friedrich, J. Sübers, J. Dippon, G. Friedel, T. Walles: Canine scan detection in the diagnosis of lung cancer: revisiting a puzzling phenomenon. In: Eur Respir J. 39, 2012, pp. 669-676.
  14. ↑ Excellent tissue engineering process for regenerative medicine Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB (May 1, 2010)
personal data
SURNAME Walles, Thorsten
BRIEF DESCRIPTION German thoracic surgeon
DATE OF BIRTH June 28, 1972
PLACE OF BIRTH Lingen