Ulrich Loos

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Ulrich Loos (born May 1, 1939 ) is a German endocrinologist and university professor whose scientific focus is on the field of thyroid diseases (thyreology). Together with Gerhard Rothenbuchner and Ernst-Friedrich Pfeiffer, he is one of the first to describe the low-T3 syndrome, the main component of the non-thyroidal illness syndrome .

Career

Loos studied medicine at the University of Heidelberg from 1960 to 1966 . In his dissertation , under the guidance of Gotthard Schettler , he dealt with the effect of the steroid methenolone on lipid metabolism . After moving to Ulm University Hospital , he headed the thyroid laboratory there since 1971 and the thyroid outpatient department since 1975. He completed his habilitation in 1982 with fundamental and clinical studies on thyroid hormone metabolism . In 1988 he was appointed adjunct professor at Ulm University. From 1971 until his retirement in 2004 he headed an endocrinological research laboratory and a scientific working group, and since 1978 he has been a senior physician at the Ulm University Hospital. Loos organized nine international scientific conferences and published numerous scientific articles and books on the physiology and pathophysiology of the thyroid gland.

In 1998 Ulrich Loos was awarded the Science-Business Cooperation Prize of Ulm University.

In the course of his scientific life he led numerous research projects on the conversion of thyroid hormones, thyroid hormone resistance , sodium-iodide symporter , thyroid stimulin and, in particular, the molecular pathology of Graves' disease and endocrine orbitopathy .

In 2004 Ulrich Loos and Werner Kress founded KreLo GmbH Medical Diagnostics, a biotechnological company that develops and produces diagnostic tools for human medicine.

source

Web links

Individual evidence

  1. ^ G. Rothenbuchner, U. Loos, WR Kiessling, J. Birk, EF Pfeiffer: The influence of total starvation on the pituitary-thyroid-axis in obese individuals. In: Acta Endocrinologica. Supplement, vol. 173, 1973, p. 144. PMID 4542076
  2. ↑ a b Bloomberg Businessweek: Company Overview of KreLo GmbH Medical Diagnostics, Ulrich Loos Executive Profile , viewed on May 7, 2015.
  3. ↑ Ulm University Hospital, Clinic for Internal Medicine I: Former employees / senior physicians ( Memento of the original from May 26, 2017 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.uniklinik-ulm.de
  4. ↑ innovations-report (July 9, 2003): High-level Scientific Conference in Reisensburg: "Hormones and Genome"
  5. ^ GR Williams, U. Loos: Proceedings of the Conference entitled Thyroid and Gonadal Hormones in Health and Disease. Blaubeuren, Germany, June 2002. In: Molecular and Cellular Endocrinology. Volume 213, Issue 1, 2003, pp. 1–114.
  6. ↑ Ulm University: Winner of the Science-Business Cooperation Prize ( Memento of the original from May 4, 2015 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. . February 12, 2015. @1@ 2Template: Webachiv / IABot / www.uni-ulm.de
  7. ↑ M. Behr, DB Ramsden, U. Loos: Deoxyribonucleic acid binding and transcriptional silencing by a truncated c-erbA beta 1 thyroid hormone receptor identified in a severely retarded patient with resistance to thyroid hormone. In: J Clin Endocrinol Metab. 82 (4), Apr 1997, pp. 1081-1087. PMID 9100577
  8. ↑ E. Breous, A. Wenzel, U. Loos: The promoter of the human sodium / iodide symporter Responds to Certain phthalate Plasticisers. In: Mol Cell Endocrinol. 244 (1-2), Dec 1, 2005, pp. 75-78. PMID 16257484
  9. ↑ E. Breous, A. Wenzel, U. Loos: Promoter cloning and characterization of the transcriptional regulation of the human thyrostimulin A2 subunit. In: Mol Cell Endocrinol. 245 (1-2), Dec 21, 2005, pp. 169-180. Epub 2005 Dec 22. PMID 16376481
  10. ↑ E. Breous, A. Wenzel, U. Loos: Graves' IgG activate upstream enhancer of the sodium / iodide symporter. In: Mol Cell Endocrinol. 213 (1), Dec 31, 2003, pp. 109-113. PMID 15062579
  11. ↑ a b c C. U. Frank, S. Braeth, JW Dietrich, D. Wanjura, U. Loos: Bridge Technology with TSH Receptor Chimera for Sensitive Direct Detection of TSH Receptor Antibodies Causing Graves' Disease: Analytical and Clinical Evaluation. In: Horm Metab Res. 16 Jun 2015. PMID 26079838 .
  12. ↑ WB Minich, U. Loos: Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis. In: Exp Clin Endocrinol Diabetes. 108 (2), 2000, pp. 110-119. PMID 10826518
  13. ↑ Bio-Pro Baden Württemberg: the early days of the 9th BioRegio-Meeting ( memento of the original from June 26, 2015 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. . March 21, 2005. @1@ 2Template: Webachiv / IABot / www.biopro.de


personal data
SURNAME Loos, Ulrich
BRIEF DESCRIPTION German endocrinologist
DATE OF BIRTH May 1, 1939