Veit Krenn

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Veit Krenn, 2013

Veit Krenn (born November 3, 1960 in Philadelphia , Pennsylvania , United States ) is a German pathologist and sculptor of Austrian origin.

Life

Veit Krenn is the son of the Viennese artist Hans Krenn (1932–2007), who worked in the Viennese "Fantastic Realists" environment. Krenn spent his childhood partly in Florida and partly in Vienna. From 1980 to 1987 Krenn studied medicine in Vienna and Bochum . In Vienna he was on 30 November 1987 on the issue of migration and determination of myogenic cells in the embryo to Dr. med. univ. doctorate . From 1988 to 1992 he worked as an assistant doctor at the Histological-Embryological Institute in Vienna. He then worked until 2000 as a research assistant at the Pathological Institute of the Julius Maximilians University of Würzburg . Wuerzburg Krenn was on 21 November 1997 with a work on the theme The expression profile of macrophages antigens, adhesion molecules and chemokines of epithelioid cell granulomas in and kleinherdigen Epitheloidzellreaktion to Dr. med. PhD. On June 26, 2000, Krenn received his habilitation there ( morphological and molecular analysis of synovial B cells in chronic synovialitis: A contribution to the understanding of the pathogenesis of osteoarthritis and rheumatoid arthritis ) and accepted a call to the Charité in Berlin. There he worked until 2005 as C3 professor for experimental infection pathology and senior physician at the Institute for Pathology. Since 2005 he has been at the Medical Care Center for Histology, Cytology and Molecular Diagnostics in Trier.

Krenn is married to Anke Krenn (née Hecker), a psychiatrist, with whom he has three children.

Work areas

Together with his colleagues at the Charité, Krenn developed the synovitis score . It is a semi-quantitative histopathological evaluation mechanism ( score ) for the diagnosis of rheumatic and non-rheumatic joint diseases .

In interdisciplinary cooperation, Krenn developed the extended consensus classification of the periprosthetic membrane , which enables the various causes that lead to the loosening of endoprostheses and a particle identification in the periprosthetic membrane, which are evaluated on the basis of histopathological features. These scores represent diagnostic scores with high sensitivity and specificity, which have sufficient interobserver reproducibility. In a current publication, the international response of the synovitis score over the last 15 years was presented. In addition, in cooperation with colleagues from rheumatology, anatomy and immunology, data on the molecular mechanisms of the inflammatory reaction were compiled.

As an artist, Krenn creates sculptures that are based on anatomical and pathological forms.

Awards

literature

  • Isabel Atzl: Zeitzeugen Charité: Working worlds of the Institute for Pathology 1952–2005. LIT Verlag, Berlin / Hamburg / Münster 2006, ISBN 3-8258-9522-X , p. 134 f. limited preview in Google Book search
  • Krenn V., Rüther W (ed.): Pathology of the musculoskeletal system . DeGruyter ISBN 978-3-11-028596-3
  • H. Hempfling, V. Krenn: Damage assessment on the movement system . Volume 1: Basics, joint surfaces, osteonecrosis, epiphyses, impingment, synovium . DeGruyter, ISBN 978-3-11-028322-8
  • H. Hempfling, V. Krenn: Damage assessment on the movement system . Volume 2: meniscus, disc, intervertebral discs, labrum, ligaments, tendons . DeGruyter, ISBN 978-3-11-029738-6
  • V. Krenn, G. Perino: Histological Diagnosis of Implant-associated Pathologies . Springer, ISBN 978-3-662-54204-0

Web links

Individual evidence

  1. ^ V. Krenn, L. Morawietz, G.-R. Burmester, RW Kinne, U. Mueller-Ladner: Synovitis score: discrimination between chronic low-grade and high-grade synovitis . In: Histopathology . tape 49 , no. 4 , October 1, 2006, ISSN  0309-0167 , p. 358-364 , doi : 10.1111 / j.1365-2559.2006.02508.x , PMID 16978198 .
  2. ↑ V. Krenn, L. Morawietz, T. Häupl, J. Neidel, I. Petersen: Grading of chronic synovitis - a histopathological grading system for molecular and diagnostic pathology . In: Pathology, Research and Practice . tape 198 , no. 5 , January 1, 2002, ISSN  0344-0338 , p. 317-325 , doi : 10.1078 / 0344-0338-5710261 , PMID 12092767 .
  3. ^ V. Krenn, L. Morawietz, G.-R. Burmester, T. Häupl: [Synovitis score: histopathological grading system for chronic rheumatic and non-rheumatic synovitis] . In: Zeitschrift fur Rheumatologie . tape 64 , no. 5 , June 1, 2005, ISSN  0340-1855 , p. 334-342 , doi : 10.1007 / s00393-005-0704-x , PMID 15965818 .
  4. ↑ Benjamin Zmistowski, Craig Della Valle, Thomas W. Bauer, Konstantinos N. Malizos, Abbas Alavi: Diagnosis of periprosthetic joint infection . In: Journal of Orthopedic Research: Official Publication of the Orthopedic Research Society . 32 Suppl 1, January 1, 2014, ISSN  1554-527X , p. S98-107 , doi : 10.1002 / jor.22553 , PMID 24464903 .
  5. ↑ NS Kalson, LA Borthwick, DA man, DJ Deehan, P. Lewis: International consensus on the definition and classification of fibrosis of the knee joint . In: The Bone & Joint Journal . 98-B, no. 11 , November 1, 2016, ISSN  2049-4408 , p. 1479-1488 , doi : 10.1302 / 0301-620X.98B10.37957 , PMID 27803223 .
  6. ↑ S. Krenn, M. Thomsen, S. Usbeck, LF Scheuber, F. Boettner: Supramacroparticulate PE in 6 different joint endoprostheses localizations: An indicator for PE damage? In: Pathology, Research and Practice . tape 213 , no. 8 , August 2017, ISSN  1618-0631 , p. 987-996 , doi : 10.1016 / j.prp.2017.03.014 , PMID 28602486 .
  7. ^ V. Krenn, P. Thomas, M. Thomsen, JP Kretzer, S. Usbeck: [Histopathological particle algorithm. Particle identification in the synovia and the SLIM] . In: Zeitschrift fur Rheumatologie . tape 73 , no. 7 , September 1, 2014, ISSN  1435-1250 , p. 639-649 , doi : 10.1007 / s00393-013-1315-6 , PMID 24821089 .
  8. ↑ TW Bauer et al .: Hip and Knee Section, Diagnosis, Laboratory Tests: Proceedings of International Consensus on Orthopedic Infections . (English) PMID 30343973 .
  9. ^ V. Krenn, L. Morawietz, G. Perino, H. Kienapfel, R. Ascherl: Revised histopathological consensus classification of joint implant related pathology . In: Pathology, Research and Practice . tape 210 , no. 12 , December 1, 2014, ISSN  1618-0631 , p. 779-786 , doi : 10.1016 / j.prp.2014.09.017 , PMID 25454771 .
  10. ^ VT Krenn, M. Liebisch, B. Kölbel, N. Renz, T. Gehrke: CD15 focus score: Infection diagnosis and stratification into low-virulence and high-virulence microbial pathogens in periprosthetic joint infection . In: Pathology, Research and Practice . January 12, 2017, ISSN  1618-0631 , doi : 10.1016 / j.prp.2017.01.002 , PMID 28343870 .
  11. ^ Krenn, Veit, Perino, Giorgio: Histological Diagnosis of Implant-associated Pathologies . Springer Verlag, 2017, ISBN 978-3-662-54204-0 .
  12. ↑ Tobias Schmidt, Aurélie Najm, Haider Mussawy, Rolf Burghardt, Nicola Oehler: General synovitis score and immunologic synovitis score reflect clinical disease activity in patients with advanced stage rheumatoid arthritis . In: Scientific Reports . tape 9 , no. 1 , June 11, 2019, ISSN  2045-2322 , p. 8448 , doi : 10.1038 / s41598-019-44895-9 , PMID 31186464 , PMC 6560084 (free full text).
  13. ^ V. Krenn, G. Perino, W. Rüther, VT Krenn, M. Huber: 15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopedics . In: Pathology, Research and Practice . tape 213 , no. 8 , August 2017, ISSN  1618-0631 , p. 874-881 , doi : 10.1016 / j.prp.2017.05.005 , PMID 28687159 .
  14. ↑ Miguel Jiménez-Alcázar, Chandini Rangaswamy, Rachita Panda, Josephine Bitterling, Yashin J. Simsek: Host DNases prevent vascular occlusion by neutrophil extracellular traps . In: Science . tape 358 , no. 6367 , December 1, 2017, ISSN  1095-9203 , p. 1202-1206 , doi : 10.1126 / science.aam8897 , PMID 29191910 .
  15. ↑ Moritz Leppkes, Christian Wall Barren, Sebastian Hirth, Stefanie Nowecki, Claudia Günther: Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis . In: Nature Communications . tape 7 , March 11, 2016, ISSN  2041-1723 , p. 10973 , doi : 10.1038 / ncomms10973 , PMID 26964500 , PMC 4793047 (free full text).
  16. ^ Niklas Kirchen, Lars Reich, Wenzel Waldstein, Thomas Hopf, Karl-Dieter Heller: [ARMD reaction patterns in knee arthroplasty: A novel hypothetical mechanism: hingiosis] . In: The orthopedist . January 9, 2020, ISSN  1433-0431 , doi : 10.1007 / s00132-019-03776-9 , PMID 31919555 .
  17. ↑ volksfreund.de: Trier pathologist receives award. In: volksfreund.de. Retrieved October 24, 2017 .
  18. ↑ L. Bause, A. Niemeier, V. Krenn: [Arthur Vick Prize 2017 of the German Society of Orthopedic Rheumatology] . In: Zeitschrift fur Rheumatologie . tape 77 , no. 2 , March 2018, ISSN  1435-1250 , p. 168-174 , doi : 10.1007 / s00393-018-0433-6 , PMID 29508053 .
  19. ↑ pixelpublic GmbH: OUP best price. Association of Southern German Orthopedists and Trauma Surgeons V., accessed on June 14, 2018 .
  20. ↑ Award-winning research highlights from orthopedics and trauma surgery. Retrieved November 13, 2018 .
personal data
SURNAME Krenn, Veit
BRIEF DESCRIPTION German pathologist
DATE OF BIRTH November 3, 1960
PLACE OF BIRTH Philadelphia