Walter M. Fitch

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Walter Monroe Fitch (born May 21, 1929 in San Diego , † March 10, 2011 in Irvine , California ) was an American molecular biologist and evolutionary researcher. He is considered the founder of molecular phylogeny .

Walter Fitch earned a bachelor's degree in chemistry from the University of California, Berkeley in 1953 and a doctorate in biochemistry in 1958 . After several years of research as a post-doctoral student , he taught from 1962 to 1986 as a professor at the School of Medicine at the University of Wisconsin – Madison . He then moved to the University of Southern California , where he was professor of biology from 1986 to 1989 and then held a chair in ecology and evolutionary biology until his death.

In the 1960s and 1970s, among other things, he dealt with theories of evolution at the molecular level . He designed computer algorithms with the help of which the close relationship of organisms could be determined using protein or nucleotide sequences and graphically illustrated in phylogenetic trees using a distance matrix (“Fitch-Margoliash method” and “Fitch parsimony algorithm”). In particular, cytochrome c served as a model case . He developed methods to distinguish homologous and analogous structures in proteins, a prerequisite for the reconstruction of a tribal history on the basis of biochemical features.

His main scientific work is the study Construction of Phylogenetic Trees , published in Science in 1967 , which is regarded as one of the founding texts of molecular phylogeny . He also worked on reconstructing the molecular evolution of HI viruses and influenza viruses .

Walter Fitch headed the newly founded journal Molecular Biology and Evolution for ten years from 1983 and was co-founder and founding chairman of the Society for Molecular Biology and Evolution in 1992 . The Walter M. Fitch Award of the Society for Molecular Biology and Evolution was named after him in 1993 . He was a member of the National Academy of Sciences of the United States, since 1991 the American Academy of Arts and Sciences , the Linnean Society of London and the American Philosophical Society .

On his death, Fitch left behind the almost completed manuscript for his book Logic, Rhetoric, and Science: And Why Creationism Fails at All Three , which was published by the University in March 2012 under the title The Three Failures of Creationism: Logic, Rhetoric, and Science of California has been released.

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  1. ^ William A. Atchley: Walter M. Fitch (1929-2011). In: Science , Volume 332, 2011, p. 804, doi: 10.1126 / science.1207426