Roswell Park Comprehensive Cancer Center: Difference between revisions

Coordinates: 42°53′50″N 78°52′01″W / 42.897185°N 78.866852°W / 42.897185; -78.866852
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BIG UPDATE: Added lots of sources, re-organized all sections, and expanded on information where I could.
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{{Redirect|RPCI|the Presbyterian denomination|Reformed Presbyterian Church of Ireland}}
{{Redirect|RPCI|the Presbyterian denomination|Reformed Presbyterian Church of Ireland}}
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{{Infobox hospital
{{Infobox hospital
| Name = Roswell Park Comprehensive Cancer Center
| Name = Roswell Park Comprehensive Cancer Center
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| Website = {{URL|https://www.roswellpark.org/}}
| Website = {{URL|https://www.roswellpark.org/}}
| Wiki-Links = [[New York state public-benefit corporations|List of NYS Public Benefit Corporations]]
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'''Roswell Park Comprehensive Cancer Center''' (founded 1898) is a [[cancer]] research and treatment center and a [[New York state public-benefit corporations|New York State public-benefit corporation]] located in [[Buffalo, New York]] and founded by [[Roswell Park (surgeon)|Roswell Park]]. Candace S. Johnson is President & Chief Executive Officer of Roswell Park Comprehensive Cancer Center. In 2019 & 2020, Roswell Park ranked #14 on U.S. News & World Report's list of the best cancer hospitals in the country, an increase from position #30 in 2018.<ref>{{Cite web|title=Roswell Park Ranks 14th on List of Nation's Best Hospitals for Cancer|url=https://www.roswellpark.org/cancertalk/201907/roswell-park-ranks-14th-list-nations-best-hospitals-cancer|access-date=2020-06-22|website=Roswell Park Comprehensive Cancer Center|language=en}}</ref><ref>{{Cite web|date=2019-07-30|title=Roswell Park says ranking on national list meaningful to doctors, patients|url=https://buffalonews.com/2019/07/30/roswell-park-says-ranking-on-national-list-meaningful-to-doctors-patients/|access-date=2020-06-22|website=The Buffalo News|language=en-us}}</ref><ref>{{Cite web|title=Roswell Park Comprehensive Cancer Center|url=https://health.usnews.com/best-hospitals/area/ny/roswell-park-cancer-institute-6211120|url-status=live|access-date=2021-05-10|website=[[U.S. News & World Report]]}}</ref> Roswell Park was the first dedicated medical facility for cancer treatment and research in the [[United States]],<ref name=":2">{{Cite news|date=April 25, 2018|title=Roswell Park celebrates 120 years with time capsule|work=[[WGRZ]]|url=https://www.wgrz.com/article/news/health/roswell-park-putting-together-time-capsule-that-will-be-opened-in-100-years/71-545629304|access-date=2021-05-10}}</ref><ref name=":0" /> and is the only [[upstate New York]] facility to hold the [[National Cancer Institute]] designation of "comprehensive cancer center." Roswell Park Comprehensive Cancer Center, which conducts clinical research on cancer as well as developing new drugs, provides advanced treatment for all forms of adult and pediatric cancer and serves as a member of the [[National Comprehensive Cancer Network]].
'''Roswell Park Comprehensive Cancer Center''' is a [[cancer]] research and treatment center located in [[Buffalo, New York]]. Founded by [[Roswell Park (surgeon)|Roswell Park]] in 1898, the center was the first in the [[United States]] to specifically focus on cancer research.<ref>{{Cite journal|last=Rusch|first=Harold P|date=1985|title=Beginnings of Cancer Research Centers in the United States|url=https://academic.oup.com/jnci/article/74/2/391/903937|journal=[[Journal of the National Cancer Institute]]|volume=74|issue=2|pages=391-403|doi=10.1093/jnci/74.2.391|quote=The first center in the United States devoted specifically for research on cancer was founded by Dr. Roswell Park in 1898. Dr. Park, a professor of surgery at the University of Buffalo (Buffalo, NY), with Mr. Edward Butler, publisher of the Buffalo Evening News, in 1897 persuaded the legislators of New York State to appropriate $7,500 for cancer research.|doi-access=free}}</ref><ref name=":2">{{Cite news|date=April 25, 2018|title=Roswell Park celebrates 120 years with time capsule|work=[[WGRZ]]|url=https://www.wgrz.com/article/news/health/roswell-park-putting-together-time-capsule-that-will-be-opened-in-100-years/71-545629304|access-date=May 10, 2021}}</ref><ref name=":0">{{Cite news|title=1898-1950|language=en|work=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/about-us/history/1898-1950|access-date=May 10, 2021}}</ref> The center, which conducts clinical research on cancer as well as the development new drugs, provides advanced treatment for all forms of adult and pediatric cancer, and serves as a member of the [[National Comprehensive Cancer Network]]. Roswell Park Comprehensive Cancer Center is currently the only [[upstate New York]] facility to hold the [[National Cancer Institute]] designation of "comprehensive cancer center".<ref>{{Cite web|date=2019|title=Roswell Park Comprehensive Cancer Center|url=https://www.cancer.gov/research/infrastructure/cancer-centers/find/roswellpark|url-status=live|access-date=May 11, 2021|website=National Cancer Institute}}</ref>


The Roswell Park campus, spread out in 15 separate buildings of approximately two million square feet, occupies {{convert|28|acre}} on the {{convert|100|acre|adj=on}} [[Buffalo Niagara Medical Campus]] (BNMC) in downtown Buffalo, and includes {{convert|1500000|sqft}} of space equally distributed between [[clinic]]al programs and research/education functions. A separate hospital building, completed in 1998, houses a diagnostic and treatment center. The campus also includes a medical research complex as well as research and education focused space.
The Roswell Park campus, spread out in 15 separate buildings of approximately two million square feet, occupies {{convert|28|acre}} on the {{convert|100|acre|adj=on}} [[Buffalo Niagara Medical Campus]] (BNMC) in downtown Buffalo, and includes {{convert|1500000|sqft}} of space equally distributed between [[clinic]]al programs and research/education functions. A separate hospital building, completed in 1998, houses a diagnostic and treatment center. The campus also includes a medical research complex as well as research and education focused spaces.


{{TOC limit|2}}
==Organization==
The Roswell Park Cancer Institute Corporation, which is the name of the New York public benefit corporation that operates the center, is guided by a 14-member board of directors (which has its own staff).<ref>{{cite web|url=https://www.roswellpark.org/about-us/board-directors|title=Roswell Park Board Page|access-date=November 6, 2018}}</ref> The management team is headed by President and CEO Candace S. Johnson, PhD, who reports to the board.<ref>{{cite web|url=https://www.roswellpark.org/about-us/executive-management-team|title=Roswell Park Management Page|access-date=November 6, 2018}}</ref> In 2017, it had operating expenses of $722.45 million, an outstanding debt of $189.67 million, and a staffing level of 2,919 people.<ref>{{cite web|url=https://www.abo.ny.gov/reports/annualreports/ABO2018AnnualReport.pdf|title=NYSABO 2018 Report|pp=16,29,44|access-date=November 6, 2018}}</ref>


==History==
==History==
In 1898, Roswell Park Comprehensive Cancer Center was established by Roswell Park, who was a professor of surgery at the [[University of Buffalo]] School of Medicine.<ref name=":1">{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=9}}</ref> Park said that "Only through a deliberate well-planned, combined attack from various directions by means fitted for such work could real advances be made and further the relationship of laboratory work, clinical study and education must be closely associated."<ref name=":1" />
[[File:Gerty Theresa Radnitz Cori (1896-1957) and Carl Ferdinand Cori.jpg|thumb|[[Gerty Cori]] and [[Carl Cori]] jointly won the 1947 [[Nobel Prize in Physiology or Medicine]] for their discovery of the [[Cori cycle]] at RPMI.]]
In 1898, Roswell Park Comprehensive Cancer Center was established by Roswell Park, who was a professor of surgery at the [[University of Buffalo]] School of Medicine.<ref name=":1">{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=9}}</ref> Park said that "Only through a deliberate well-planned, combined attack from various directions by means fitted for such work could real advances be made and further the relationship of laboratory work, clinical study and education must be closely associated."
<ref name=":1" />


Research started in three rooms in the University of Buffalo School of Medicine but not long thereafter, it outgrew the rooms. Seeing the importance of dedicated cancer research, select Buffalo citizens donated funds to purchase land and construct a new building. The largest contributor was Mrs. William Gratwick (wife of William H. Gratwick, the founder of Gratwick, Smith & Fryer Lumber Co.), who donated $25,000. The Gratwick Research Laboratory of the University of Buffalo was constructed in 1901 and was located at High and Elm streets.<ref>{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=16}}</ref>
Research started in three rooms in the University of Buffalo School of Medicine but not long thereafter, it outgrew the rooms. Seeing the importance of dedicated cancer research, select Buffalo citizens donated funds to purchase land and construct a new building. The largest contributor was Mrs. William Gratwick (wife of William H. Gratwick, the founder of Gratwick, Smith & Fryer Lumber Co.), who donated $25,000. The Gratwick Research Laboratory of the University of Buffalo was constructed in 1901 and was located at High and Elm streets.<ref>{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=16}}</ref>
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Park wrote books, gave lectures, and was the administrator at the cancer research center. In 1904, Park stepped down and Harvey R. Gaylord took over as the center's second director. Park remained as the chairman of the board of trustees.<ref>{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=21}}</ref>
Park wrote books, gave lectures, and was the administrator at the cancer research center. In 1904, Park stepped down and Harvey R. Gaylord took over as the center's second director. Park remained as the chairman of the board of trustees.<ref>{{Cite book|last=Mirand|first=Edwin A|title=Legacy And History Of Roswell Park Cancer Institute, 1898-1998|publisher=[[The Donning Company]]|year=1998|isbn=9781578642816|location=Virginia Beach, VA|pages=21}}</ref>


==Centers of research==
=== Notable facts ===
* Founded in 1898 as the world's first institute devoted exclusively to cancer research<ref>{{Cite news|title=1898-1950|language=en|work=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/about-us/history/1898-1950|access-date=2021-05-10}}</ref>
[[File:Roswell clinical.JPG|thumb|Scott Bieler Clinical Sciences Center]]
* Dr. Gerty Cori was the first woman to receive the Nobel Prize in Physiology or Medicine.<ref>{{Cite web|title=Nobel Prize awarded women|url=https://www.nobelprize.org/prizes/lists/nobel-prize-awarded-women/|url-status=live|access-date=May 12, 2021|website=[[The Nobel Prize]]|publisher=Nobel Prize Outreach AB}}</ref>
Roswell Park's centers include the Breast Service; [[Chemotherapy]]/Infusion; [[Dermatology]], Soft Tissue Melanoma, Thoracic; Lower Gastrointestinal; Upper Gastrointestinal; Genito-Urology; Head & Neck; Dentistry and Maxillofacial Prosthetics; Pediatric; Gynecology and [[Hematology]]/[[Neurology]]/Pain. Supporting these centers are clinical resources that include [[Anesthesiology]] & Critical Care Medicine; Blood Bank/[[Plateletpheresis]]; Clinical Research Services; Community Cancer Resource Center; Diagnostic Imaging; Genetics Counseling/Testing; Infectious Disease Service; [[Nursing]]; Pain Medicine; [[Pathology]] & Laboratory Medicine; Patient Advocacy; [[Photodynamic Therapy]]; Psychosocial Support; [[Radiation]] [[Oncology]]; [[Physical medicine and rehabilitation|Rehabilitation]] (physical, occupational and speech therapy); and [[Therapeutics]] (experimental).
* The center's first female leader, Candace S. Johnson, PhD, was named President & CEO in February 2015.<ref>{{Cite news|title=Roswell Park Announces Candace S. Johnson, PhD, as Institute’s 15th President & CEO|language=en|work=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201502-roswell-park-announces-candace-s-johnson-phd-institutes-15th-president-ceo|access-date=2021-05-10}}</ref>
* First example of direct government interest (New York State) in cancer research
* Leads New York State in the number of robotic cystectomies performed<ref>{{Cite web|title=Bladder Cancer Surgery|url=https://www.roswellpark.org/cancer/bladder/treatment/surgery|url-status=live|access-date=May 13, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>
* Established one of the nation's first long-term survivors clinics for childhood cancer patients<ref>{{Cite news|date=February 11, 2011|title=Roswell Park Creates Center of Excellence for Adolescents and Young Adults with Cancer|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201102-roswell-park-creates-center-excellence-adolescents-young-adults-cancer|access-date=May 13, 2021}}</ref>
* Member of international team of scientists who produced the landmark studies of the Human Genome project

==Discoveries and advancements in cancer care==

=== Discovery of how the human body converts glucose to glycogen ===
[[File:Gerty Theresa Radnitz Cori (1896-1957) and Carl Ferdinand Cori.jpg|thumb|[[Gerty Cori]] and [[Carl Cori]] jointly won the 1947 [[Nobel Prize in Physiology or Medicine]] for their discovery of the way in which the body converts glucose to glycogen.]]
Drs. [[Gerty Cori|Gerty]] and [[Carl Ferdinand Cori|Carl Cori]] jointly won the 1947 [[Nobel Prize in Physiology or Medicine]], "for their discovery of the course of the catalytic conversion of glycogen."<ref>{{Cite web|title=The Nobel Prize in Physiology or Medicine 1947|url=https://www.nobelprize.org/prizes/medicine/1947/summary/|url-status=live|access-date=May 12, 2021|website=[[The Nobel Prize]]|publisher=Nobel Prize Outreach AB}}</ref> Their research leading to the discovery began during their tenure at Roswell Park (then called the New York State Institute for the Study of Malignant Diseases), from 1922 to 1931.<ref>{{Cite web|title=Gerty Cori - Biographical|url=https://www.nobelprize.org/prizes/medicine/1947/cori-gt/biographical/|url-status=live|access-date=May 10, 2021|website=[[The Nobel Prize]]|publisher=Nobel Prize Outreach AB}}</ref>

=== Alternative breast cancer treatments ===
[[Thomas Dao]] (1921–2009), served as director of the breast surgery department from 1957 to 1988, where he developed [[breast cancer]] treatment alternatives.<ref>{{Cite news|last=Hevesi|first=Dennis|date=July 25, 2009|title=Dr. Thomas Dao, Expert on Treatment of Breast Cancer, Dies at 88|work=[[The New York Times]]|department=Health|url=https://www.nytimes.com/2009/07/26/health/26dao.html|url-access=subscription|access-date=July 26, 2009}}</ref>

=== Development of photodynamic therapy ===
In 1975, Dr. Thomas Dougherty successfully treated preclinical models of cancer using [[photodynamic therapy]] (PDT) techniques for the first time.<ref>{{Cite journal|last=Dougherty|first=Thomas|last2=Grindey|first2=G|last3=Fiel|first3=R|last4=Weishaupt|first4=K|last5=Boyle|first5=D|date=1955|title=Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light|url=https://pubmed.ncbi.nlm.nih.gov/1159805/|journal=[[Journal of the National Cancer Institute]]|volume=55|issue=1|pages=115-121|doi=10.1093/jnci/55.1.115|pmid=1159805|via=PubMed|doi-access=free}}</ref><ref>{{Cite web|title=Remembering Dr. Dougherty, Chief Emeritus, PDT Center|url=https://photobiology.org/remembering-dr-dougherty-chief-emeritus-pdt-center/|url-status=live|access-date=May 11, 2021|website=[[American Society for Photobiology]]}}</ref> In 1978, he conducted the first PDT clinical trial.<ref>{{Cite journal|last=Dougherty|first=Thomas|last2=Kaufman|first2=Jerome|last3=Goldfarb|first3=Abraham|last4=Weishaupt|first4=Kenneth|last5=Boyle|first5=Donn|last6=Mittleman|first6=Arnold|date=1987|title=Photoradiation Therapy for the Treatment of Malignant Tumors|url=https://cancerres.aacrjournals.org/content/38/8/2628.full-text.pdf|journal=[[Cancer Research (journal)|Cancer Research]]|volume=38|issue=8|pages=2628-2635|pmid=667856|via=PubMed}}</ref><ref>{{Cite web|title=1970s & 1980s|url=https://www.roswellpark.org/about-us/history/1970s-1980s|url-status=live|access-date=May 11, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref> Today, PDT is an FDA-approved method for treating specific kinds of cancer, and is used around the world.

=== Discovery of PSA ===
Research resulting in the discovery of the [[prostate-specific antigen]] (PSA) was led by Dr. T. Ming Chu in the 1970s.<ref>{{Cite web|title=From the History Books: Blood Test Gives Urologists a New Way to Detect Prostate Cancer|url=https://urologichistory.museum/histories/diagnosis/psa|url-status=live|access-date=May 11, 2021|website=The William P. Didusch Center for Urologic History|publisher=[[American Urological Association]]|quote=In 1979, Chu's colleagues, led by M.C. Wang, characterized and purified the antigen, and in 1980, Lawrence D. Papsidero and fellow scientists confirmed its presence in the blood of prostate cancer patients. Amidst that activity, Chu introduced the PSA test, a screen that picks up early prostate cancer by detecting elevated levels of PSA in the blood.}}</ref> His team subsequently developed a way to detect the PSA protein in blood as a simple diagnostic test.<ref>{{Cite web|last=Roswell Park Comprehensive Cancer Center|date=March 30, 2021|title=T. Ming Chu: The Man Behind the PSA Test|url=https://cancerhistoryproject.com/people/the-man-behind-the-psa-test/|url-status=live|access-date=May 11, 2021|website=Cancer History Project}}</ref> Since its FDA approvals in 1986 and 1994, an estimated one billion PSA tests have been given.

=== Research on 5-fluorouracil + leucovorin ===
Biochemist Marie Hakala, PhD<ref>{{Cite web|title=Marie T. Hakala-Zakrzewski|url=https://www.legacy.com/us/obituaries/buffalonews/name/marie-hakala-zakrzewski-obituary?pid=173883143|url-status=live|access-date=May 12, 2021|website=[[The Buffalo News]]|publisher=Legacy.com}}</ref><ref>{{Cite web|title=In Memoriam: Marie Hakala-Zakrzewski|url=https://www.aacr.org/professionals/membership/in-memoriam/hakala-zakrzewski-marie-obituary/|url-status=live|access-date=May 12, 2021|website=[[American Association for Cancer Research]]}}</ref> first observed that 5-fluorouracil becomes more effective in treating cancer cells when calcium leucovorin is added.<ref>{{Cite journal|last=Evans|first=Mark|last2=Laskin|first2=Jeffrey|last3=Hakala|first3=Marie|date=September 1981|title=Effects of Excess Folates and Deoxyinosine on the Activity and Site of Action of 5-Fluorouracil|url=https://cancerres.aacrjournals.org/content/41/9_Part_1/3288.long|journal=[[Cancer Research (journal)|Cancer Research]]|volume=41|issue=9|pages=3288-3295|pmid=6973389|via=[[PubMed]]}}</ref><ref>{{Cite journal|last=Berger|first=S|last2=Hakala|first2=Marie|date=May 1990|title=Calcium leucovorin and 5-fluorouridine cytotoxicity|url=https://pubmed.ncbi.nlm.nih.gov/2242115/|journal=Journal of the South Carolina Medical Association|volume=86|issue=5|pages=284-289|pmid=2242115|via=[[PubMed]]}}</ref> This discovery paved the way for the development of 5-FU + leucovorin therapy, which was for many years the gold standard of chemotherapy for colorectal cancer.

==Organization==

=== Mission ===
The mission of Roswell Park is to "eliminate cancer's grip on humanity by unlocking its secrets through personalized approaches and unleashing the healing power of hope"<ref>{{Cite web|title=Mission & Values|url=https://www.roswellpark.org/about-us/mission-values|url-status=live|access-date=May 11, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>.


=== Structure ===
Roswell Park Comprehensive Cancer Center also offers specialized treatments, services and therapies including: High-dose Chemotherapy; Photodynamic Therapy; [[Gamma Knife]]; Follow-up Clinic for Long- term Survivors of Childhood Cancer; a Regional Center for [[Maxillofacial]] [[Prosthetics]]; Clinical Genetics Testing and Counseling; the Center for HIV-related Malignancies; Lymphedema Clinic; Balloon [[Kyphoplasty]]; [[Brain Mapping]]; [[cancer pain|Cancer Pain]] Management Service; High Risk Breast Clinic; Intraoperative [[MRI]]; Minimally Invasive Surgical Suite; [[Mohs Surgery]];
The Roswell Park Cancer Institute Corporation, which is the name of the [[New York state public-benefit corporations|New York State public-benefit corporation]] that operates the center, is guided by a 14-member board of directors (which has its own staff).<ref>{{cite web|url=https://www.roswellpark.org/about-us/board-directors|title=Roswell Park Board Page|access-date=November 6, 2018}}</ref> The management team is headed by President and CEO Candace S. Johnson, PhD, who reports to the board.<ref>{{cite web|url=https://www.roswellpark.org/about-us/executive-management-team|title=Roswell Park Management Page|access-date=November 6, 2018}}</ref> In 2017, it had operating expenses of $722.45 million, an outstanding debt of $189.67 million, and a staffing level of 2,919 people.<ref>{{cite web|url=https://www.abo.ny.gov/reports/annualreports/ABO2018AnnualReport.pdf|title=NYSABO 2018 Report|pp=16,29,44|access-date=November 6, 2018}}</ref>
[[Robotic Surgery]] and Colorectal Cancer Risk Management Clinic.


==Vital statistics==
=== Reputation ===
Roswell Park Comprehensive Cancer Center has received numerous accolades for the quality of healthcare provided.
A comparison of vital statistics for this 233-bed hospital among 2020, 2017 and 2013 shows:<ref>{{Cite web
|url=http://www.roswellpark.org/about-us/vital-statistics|title=Vital Statistics|publisher=Roswell Park Comprehensive Cancer Center
|access-date=2021-05-10|language=en}}</ref>
* ''Roswell'' is one of Western New York's Top 20 Employers. About 10% of their staff have been working for ''Roswell'' more than 25 years (average of 9.26 years of service). They have more than 3,000 employees, of whom about 10% are faculty members and 20% nurses.
* More than 500 projects are funded annually, with about $93 million in grants per year. ''Roswell'' has a growing number of patents: 79 as of 2020.
* The average length of stay has been growing (7.4, 7.7, 8 days). The hospital has about 5,200 admissions, 4,200 surgical procedures, and 240,000 outpatient visits per year.


* In 2020, Roswell Park ranked #14 on [[U.S. News & World Report|U.S. News & World Report's]] list of the best cancer hospitals in the country,<ref>{{Cite web|title=Roswell Park Ranks 14th on List of Nation's Best Hospitals for Cancer|url=https://www.roswellpark.org/cancertalk/201907/roswell-park-ranks-14th-list-nations-best-hospitals-cancer|url-status=live|access-date=June 22, 2020|website=Roswell Park Comprehensive Cancer Center|language=en}}</ref><ref>{{Cite web|date=July 30, 2019|title=Roswell Park says ranking on national list meaningful to doctors, patients|url=https://buffalonews.com/2019/07/30/roswell-park-says-ranking-on-national-list-meaningful-to-doctors-patients/|url-status=live|access-date=June 22, 2020|website=The Buffalo News|language=en-us}}</ref><ref>{{Cite web|title=Roswell Park Comprehensive Cancer Center|url=https://health.usnews.com/best-hospitals/area/ny/roswell-park-cancer-institute-6211120|url-status=live|access-date=May 10, 2021|website=[[U.S. News & World Report]]}}</ref> and was ranked High Performing in the areas of colon cancer surgery<ref>{{Cite web|title=Roswell Park Comprehensive Cancer Center Colon Cancer Surgery Scorecard|url=https://health.usnews.com/best-hospitals/area/ny/roswell-park-cancer-institute-6211120/colon-cancer-surgery|url-status=live|access-date=May 11, 2021|website=[[U.S. News & World Report]]}}</ref> and lung cancer surgery.<ref>{{Cite web|title=Roswell Park Comprehensive Cancer Center Lung Cancer Surgery Scorecard|url=https://health.usnews.com/best-hospitals/area/ny/roswell-park-cancer-institute-6211120/lung-cancer-surgery|url-status=live|access-date=May 11, 2021|website=[[U.S News & World Report]]}}</ref>
They had 441 active volunteers in 2017.
* Roswell Park has received recognition from [[Blue Cross Blue Shield Association|Blue Cross Blue Shield]] as a Blue Distinction Center for Cancer Care,<ref>{{Cite web|date=January 27, 2021|title=Blue Distinction Centers for Cancer Care - Directory of Providers|url=https://www.bcbs.com/sites/default/files/file-attachments/page/Cancers.Providers-042621.pdf|url-status=live|access-date=May 11, 2021|website=BlueCross BlueShield|publisher=[[Blue Cross Blue Shield Association]]|page=15|type=PDF}}</ref> Blood and Marrow Transplants,<ref>{{Cite web|date=April 14, 2021|title=Blue Distinction Centers for Transplants - Directory of Providers|url=https://www.bcbs.com/sites/default/files/file-attachments/page/Transplants.Providers-042621.pdf|url-status=live|access-date=May 11, 2021|website=BlueCross BlueShield|publisher=[[Blue Cross Blue Shield Association]]|page=17|type=PDF}}</ref> and Cellular Immunotherapy.<ref>{{Cite web|date=March 31, 2021|title=Blue Distinction Centers for Cellular Immunotherapy - Directory of Providers|url=https://www.bcbs.com/sites/default/files/file-attachments/page/CelluarImmunotherapy.Providers-040121.pdf|url-status=live|access-date=May 11, 2021|website=BlueCross BlueShield|publisher=[[Blue Cross Blue Shield Association]]|page=3|type=PDF}}</ref>
* Roswell Park is recognized as an Age-Friendly Health System by the [[Patient_safety_organization#Institute_for_Healthcare_Improvement|Institute for Healthcare Improvement]].<ref>{{Cite web|date=2021|title=Health Systems Recognized by IHI|url=http://www.ihi.org/Engage/Initiatives/Age-Friendly-Health-Systems/Pages/Background.aspx|url-status=live|access-date=May 11, 2021|website=[[Patient_safety_organization#Institute_for_Healthcare_Improvement|Institute for Healthcare Improvement]]}}</ref>
* The [[American College of Radiology]] has recognized Roswell Park as a Breast Cancer Center of Excellence.<ref>{{Cite web|title=Accredited Facility Search|url=https://accreditationfacilitylist.acr.org/|url-status=live|access-date=May 12, 2021|website=[[American College of Radiology]]|type=XLS}}</ref>
* Roswell Park is recognized as an [[Optum]] Cancer Center of Excellence.<ref>{{Cite web|date=2021|title=Cancer Centers of Excellence Network|url=https://cmcnetworkmanagementtool.uhc.com/clarity-fhcp/standardNetworkMap.do?product=CRS&population=&designation=COE&lobCode=COMM|url-status=live|access-date=May 12, 2021|website=[[Optum]]}}</ref>
* The [[Lung Cancer Alliance]] has recognized Roswell Park as a Screening Center of Excellence.<ref>{{Cite web|title=Screening Centers|url=https://go2foundation.org/risk-early-detection/screening-centers/|url-status=live|access-date=May 12, 2021|website=GO2 Foundation For Lung Cancer}}</ref>
*Roswell Park is certified as a Quality Oncology Practice Initiative by the [[American Society of Clinical Oncology]].<ref>{{Cite web|title=QOPI Certified Practices|url=https://www.google.com/maps/d/u/0/viewer?mid=1uROz9-xM_8xfbYndl7WkRn_OR5k&ll=40.35781111772134%2C-47.78678080045665&z=4|url-status=live|access-date=May 12, 2021|website=[[American Society of Clinical Oncology|American Society of Clinical Oncology and Association for Clinical Oncology]]}}</ref>


=== Accreditation ===
==Accreditations and certifications==
{{div col|colwidth=30em}}
{{div col|colwidth=30em}}
* [[Accreditation Council for Continuing Medical Education]]
* [[Accreditation Council for Continuing Medical Education]]
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* [[Association for Assessment and Accreditation of Laboratory Animal Care International]] (AAALAC International)
* [[Association for Assessment and Accreditation of Laboratory Animal Care International]] (AAALAC International)
* Association of American Blood Banks
* Association of American Blood Banks
* Blue Distinction Center for Complex and Rare Cancers
* Blue Distinction Center for Transplants
* Cancer Immunotherapy Trials Network Member (CITN)
* Cancer Immunotherapy Trials Network Member (CITN)
* Commission on Cancer of the American College of Surgeons<ref>{{Cite news|url=https://www.facs.org/institute/6414|title=Roswell Park Comprehensive Cancer Center|work=American College of Surgeons|access-date=2021-05-10|language=en}}</ref>
* Commission on Cancer Accredited Program - American College of Surgeons<ref>{{Cite news|url=https://www.facs.org/institute/6414|title=Roswell Park Comprehensive Cancer Center|work=American College of Surgeons|access-date=2021-05-10|language=en}}</ref>
* Foundation for the Accreditation of Cellular Therapy (FACT)
* Foundation for the Accreditation of Cellular Therapy (FACT)
* [[Joint Commission on Accreditation of Healthcare Organizations]]
* Gold Seal of Approval - [[Joint Commission on Accreditation of Healthcare Organizations]]
* Palliative Care Certification - [[Joint Commission on Accreditation of Healthcare Organizations]]
* Laboratory Accreditation - [[Joint Commission on Accreditation of Healthcare Organizations]]
* [[National Cancer Institute]]-designated Comprehensive Cancer Center<ref>{{Cite news|url=https://www.cancer.gov/research/infrastructure/cancer-centers/find/roswellpark|title=Roswell Park Comprehensive Cancer Center|work=National Cancer Institute|access-date=2021-05-10|language=en}}</ref>
* [[National Cancer Institute]]-designated Comprehensive Cancer Center<ref>{{Cite news|url=https://www.cancer.gov/research/infrastructure/cancer-centers/find/roswellpark|title=Roswell Park Comprehensive Cancer Center|work=National Cancer Institute|access-date=2021-05-10|language=en}}</ref>
* [[National Comprehensive Cancer Network]] Member Institution<ref>{{Cite news|url=https://www.nccn.org/members/profile?groupid=18|title=Roswell Park Comprehensive Cancer Center|work=National Comprehensive Cancer Network|access-date=2021-05-10|language=en}}</ref>
* [[National Comprehensive Cancer Network]] Member Institution<ref>{{Cite news|url=https://www.nccn.org/members/profile?groupid=18|title=Roswell Park Comprehensive Cancer Center|work=National Comprehensive Cancer Network|access-date=2021-05-10|language=en}}</ref>
* [[National Marrow Donor Program]]<ref>{{cite web |url=https://bethematch.org/tcdirectory/index/130/ |title=Be The Match - Roswell Park Comprehensive Cancer Center |author=<!--Not stated--> |website=Be The Match |publisher=National Marrow Donor Program |access-date=2021-05-10}}</ref>
* [[National Marrow Donor Program]]<ref>{{cite web |url=https://bethematch.org/tcdirectory/index/130/ |title=Be The Match - Roswell Park Comprehensive Cancer Center |author=<!--Not stated--> |website=Be The Match |publisher=National Marrow Donor Program |access-date=2021-05-10}}</ref>
* Society of Surgical Oncology - Surgical Oncology Training Program
* Society of Surgical Oncology - Surgical Oncology Training Program
{{div col end}}
* National Accreditation Program for Breast Cancers{{div col end}}


==Patient care==
==International collaborations==
[[File:Roswell clinical.JPG|thumb|Scott Bieler Clinical Sciences Center]]
===Training and education===
Roswell Park provides comprehensive care for a wide range of cancers.<ref>{{Cite web|title=Cancer Types|url=https://www.roswellpark.org/cancer|url-status=live|access-date=May 11, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>
{{div col|colwidth=30em}}
* Lakeshore Cancer Center, Lagos, Nigeria (Research and Training; Quality Oversight)
* King Fahad Specialist Hospital, Dammam, Saudi Arabia (Training Programs)
* Institute of Materia Medica of Nanyang Normal University, China (Training Programs)
* Saudi Cancer Foundation, Eastern Province, Saudi Arabia (Joint Symposium)
* Shawsand Medical Centre, Port Harcourt, Nigeria (Prostate Cancer Surgical Training)
* [[King Hussein Cancer Center]], Amman, Jordan (Network Affiliate)
* King Hussein Cancer Biotechnology Institute, Amman, Jordan (Network Affiliate; Research and Clinical Programs)
* [[University of Puerto Rico]], Río Piedras Campus (Education)
* [[Zhejiang University]], Hangzhou, China (Research Programs)
* Societé Internationale d’Urologie (Robot-Assisted Surgery Training Program)
{{div col end}}


{{div col|colwidth=25em}}
===Stacey Scott Lung Cancer Registry===
* [[British Columbia Cancer Agency]], Vancouver, Canada
* [[Adrenal tumor|Adrenal Cancer]]
* [[Anal Cancer]]
* [[Vrije Universiteit]], Amsterdam, The Netherlands
* [[Bladder Cancer]]
* [[Brain tumor|Brain Cancer]]
* [[Breast Cancer]]
* [[Cervical Cancer]]
* [[Chronic Lymphocytic Leukemia]] (CLL)
* [[Colorectal cancer|Colon & Rectal Cancer]]
* [[Esophageal Cancer]]
* [[Fallopian tube cancer|Fallopian Tube Cancer]]
* [[Gallbladder cancer|Gallbladder]] & [[Cholangiocarcinoma|Bile Duct Cancers]]
* [[Head and neck cancer|Head & Neck Cancer]]
* [[Kidney Cancer]]
* [[Leukemia]] & [[Tumors of the hematopoietic and lymphoid tissues|Other Blood Disorders]]
* [[Liver Cancer]]
* [[Lung Cancer]]
* [[Lymphoma]]
* [[Mediastinal tumors|Mediastinal Tumors]]
* [[Melanoma]]
* [[Mesothelioma]]
* [[Multiple Myeloma]]
* [[Myelodysplastic syndrome|Myelodysplastic Syndromes]]
* [[Neuroendocrine tumor|Neuroendocrine Tumors]]
* [[Ovarian Cancer]]
* [[Pancreatic Cancer]]
* [[Childhood cancer|Pediatric Cancer]] & [[Childhood leukemia|Blood Disorders]]
* [[Penile cancer|Penile Cancer]]
* [[Prostate Cancer]]
* [[Sarcoma]] & [[Soft-tissue sarcoma|Other Soft Tissue Tumors]]
* [[Skin cancer|Skin Cancers other than Melanoma]]
* [[Spinal tumor|Spinal Tumors]]
* [[Stomach Cancer]]
* [[Testicular Cancer]]
* [[Thymus#Cancer|Thymus Cancer]]
* [[Thyroid cancer|Thyroid]] & [[Parathyroid Cancer]]
* Undiagnosed Cancers
* [[Urethral Cancer]]
* [[Uterine cancer|Uterine]] & [[Endometrial Cancer]]
* [[Vaginal Cancer]]
* [[Vulvar Cancer]]{{div col end}}


=== Specialized treatments ===
==Historical facts==
Roswell Park offers specialized treatments, services and therapies to treat cancer, as well as services to support patients undergoing cancer treatment.<ref>{{Cite web|title=Treatments at Roswell Park|url=https://www.roswellpark.org/cancer-care/treatments|url-status=live|access-date=May 11, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref><ref>{{Cite web|title=Support|url=https://www.roswellpark.org/cancer-care/support|url-status=live|access-date=May 11, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>
{{div col|colwidth=25em}}
* [[Endoscopy|Advanced Endoscopy]]
* [[Anesthesiology]] & Critical Care Medicine
* [[Vertebral_augmentation|Balloon Kyphoplasty]]
* Blood Bank/[[Plateletpheresis]]
* [[Hematopoietic stem cell transplantation|BMT]] & [[Cell therapy|Cellular Therapy]]
* 3-D [[Brain Mapping]]
* [[cancer pain|Cancer Pain]] Management Service
* Dentistry and [[Maxillofacial]] [[Prosthetics]]
* [[Therapeutics|Experimental Therapeutics]]
* Follow-up Clinic for Long-term Survivors of Childhood Cancer
* [[Genetic testing|Genetic Screening]], [[Genetic counseling|Counseling]], and [[DNA bank|DNA Banking]]
* [[Clinical trial|Clinical Trials]]
* Community Cancer Resource Center
* [[Medical imaging|Diagnostic Radiology]]
* [[Gamma Knife]]
* High-Risk Breast Cancer Program
* High-Risk Lung Cancer Program
* High-Risk Ovarian Cancer Program
* High-Risk Pancreas Cancer Program
* [[Minimally invasive procedure|Minimally Invasive]] Surgical Suite
* [[Immunotherapy]]
* [[Alternative_medicine#Integrative_medicine|Integrative Medicine]]
* [[Interventional pulmonology|Interventional Pulmonology]]
* [[Interventional radiology|Interventional Radiology]]
* [[Mohs Surgery]]
* [[Nuclear medicine|Nuclear Medicine]]
* [[Nursing]]
* [[Pathology]] & Laboratory Medicine
* [[Patient advocacy|Patient Advocates]] & [[Medical social work|Social Workers]]
* [[Personalized_medicine#Cancer_genomics|Personalized Medicine]]
* [[Photodynamic Therapy]]
* [[Psycho-oncology|Psychosocial Support]]
* [[Radiation]] [[Oncology]]
* [[Physical medicine and rehabilitation|Rehabilitation]] Services including physical, occupational and speech therapy
* [[Robotic Surgery]]
* [[Smoking cessation|Tobacco Cessation]] Resources
* Women's and Men's Sexual Health Clinics for Cancer Survivors{{div col end}}


==Collaborations==
===Previous names===
* New York State Pathological Laboratory of the University of Buffalo, 1898<ref name=":2" /><ref name=":0">{{Cite news|url=https://www.roswellpark.org/about-us/history/1898-1950|title=1898-1950|work=Roswell Park Comprehensive Cancer Center|access-date=2021-05-10|language=en}}</ref>
* The Gratwick Research Laboratory, 1900
* State Institute for the Study of Malignant Disease, 1911
* Roswell Park Memorial Institute (RPMI), 1946
* Roswell Park Cancer Institute (RPCI), 1992


=== CIMAvax ===
Roswell Park was the first American institution to receive FDA permission to conduct clinical trials of [[CimaVax-EGF|CIMAvax]], a Cuban medical therapy developed by Centro de Immunologica Molecular, La Habana, Cuba.<ref>{{Cite news|date=October 26, 2016|title=Gov. Cuomo Announces Landmark Roswell Park Study Bringing Cuban Lung Cancer Vaccine to U.S. Patients, and Approval of Historic U.S. Government License Authorizing U.S.–Cuba Commercial Partnership to Fast-Track Biotech Development|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201610-gov-cuomo-announces-landmark-roswell-park-study-bringing-cuban-lung-cancer-vaccine|access-date=May 10, 2021}}</ref><ref>{{Cite news|last=Kroll|first=David|date=November 26, 2016|title=Fidel Castro-Supported Lung Cancer Vaccine To Be Tested In U.S. Clinical Trials|language=en|work=[[Forbes]]|url=https://www.forbes.com/sites/davidkroll/2016/11/26/fidel-castro-supported-lung-cancer-vaccine-to-be-tested-in-u-s-clinical-trials/?sh=37a0278460de|access-date=May 10, 2021}}</ref>


=== Ovarian Cancer SPORE ===
===Historical firsts===
The Ovarian Cancer SPORE is a collaboration between Roswell Park and [[University of Pittsburgh Cancer Institute]] (UPCI). The SPORE project includes multiple research projects, core supportive structures, and career development programs.<ref>{{Cite web|title=Roswell Park - UPCI Ovarian Cancer SPORE Overview|url=https://www.roswellpark.org/research/roswell-park-upci-ovarian-cancer-spore/spore-overview|url-status=live|access-date=May 13, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>
{{div col|colwidth=30em}}

* Founded in 1898 as the world's first institute devoted exclusively to cancer research<ref>{{Cite news|url=https://www.roswellpark.org/about-us/history/1898-1950|title=1898-1950|work=Roswell Park Comprehensive Cancer Center|access-date=2021-05-10|language=en}}</ref>
=== Cancer Registries ===
* The center's first female leader, Candace S. Johnson, PhD, was named President & CEO in February 2015.<ref>{{Cite news|url=https://www.roswellpark.org/newsroom/201502-roswell-park-announces-candace-s-johnson-phd-institutes-15th-president-ceo|title=Roswell Park Announces Candace S. Johnson, PhD, as Institute’s 15th President & CEO|work=Roswell Park Comprehensive Cancer Center|access-date=2021-05-10|language=en}}</ref>

* First American institution to receive FDA permission to sponsor testing of [[CimaVax-EGF|CIMAvax]], a Cuban medical therapy in the US<ref>{{Cite news|url=https://www.roswellpark.org/newsroom/201610-gov-cuomo-announces-landmark-roswell-park-study-bringing-cuban-lung-cancer-vaccine|title=Gov. Cuomo Announces Landmark Roswell Park Study Bringing Cuban Lung Cancer Vaccine to U.S. Patients, and Approval of Historic U.S. Government License Authorizing U.S.–Cuba Commercial Partnership to Fast-Track Biotech Development|date=2016-10-26|work=Roswell Park Comprehensive Cancer Center|access-date=2021-05-10|language=en}}</ref><ref>{{Cite news|url=https://www.forbes.com/sites/davidkroll/2016/11/26/fidel-castro-supported-lung-cancer-vaccine-to-be-tested-in-u-s-clinical-trials/?sh=37a0278460de|title=Fidel Castro-Supported Lung Cancer Vaccine To Be Tested In U.S. Clinical Trials|date=2016-11-26|work=Forbes|access-date=2021-05-10|language=en}}</ref>
====Stacey Scott Lung Cancer Registry====
* First example of direct government interest (New York State) in cancer research
* Pioneered the prostate specific antigen (PSA) test<ref>{{Cite news|url=https://www.roswellpark.org/cancertalk/201909/man-behind-psa-test|title=The man behind the PSA test|work=Roswell Park Comprehensive Cancer Center|access-date=2021-05-10|language=en}}</ref>
Together with the [[British Columbia Cancer Agency]], Vancouver, Canada and [[Vrije Universiteit]], Amsterdam, The Netherlands, Roswell Park manages the Stacey Scott Lung Cancer Registry.<ref>{{Cite web|title=Stacey Scott Lung Cancer Registry|url=https://www.roswellpark.org/cancer/lung/resources-services/lung-cancer-registry|url-status=live|access-date=May 12, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>

* Pioneered photodynamic therapy (PDT)<ref>{{Cite news|url=https://photobiology.org/remembering-dr-dougherty-chief-emeritus-pdt-center/|title=Remembering Dr. Dougherty, Chief Emeritus, PDT Center|work=American Society for Photobiology|access-date=2021-05-10|language=en}}</ref>
==== Familial Ovarian Cancer Registry ====
* Pioneered 5-FU and leucovorin for colorectal cancer – for many years the gold standard chemotherapy for this disease
Founded in 1990 by Dr. Steven Piver, the Familial Ovarian Cancer Registry houses information relating to family history and lifestyle of patients and families with histories of ovarian cancer.<ref>{{Cite web|title=About The Familial Ovarian Cancer Registry|url=https://www.roswellpark.org/ovarian-cancer-registry/about-registry|url-status=live|access-date=May 13, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref><ref>{{Cite web|title=What is the Registry?|url=https://www.roswellpark.org/ovarian-cancer-registry/what-registry|url-status=live|access-date=May 13, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>
* Leads the nation in the number of robotic cystectomies performed

* Established one of the nation's first long-term survivors clinics for childhood cancer patients
=== Research and training collaborations ===
* Member of international team of scientists who produced the landmark studies of the Human Genome project{{div col end}}
Roswell Park collaborates with institutions around the world to strengthen cancer training and research programs.<ref>{{Cite web|title=International Collaborations|url=https://www.roswellpark.org/become-patient/locations/international-collaborations|url-status=live|access-date=May 12, 2021|website=Roswell Park Comprehensive Cancer Center}}</ref>


* Centro de Immunologia Molecular (CIM), Playa, La Habana, Cuba
==Notable staff==
* [[Debrecen Medical University]], Debrecen, Hungary
*Drs. Gerty and Carl Cori jointly won the 1947 Nobel Prize in Physiology or Medicine, "for their discovery of the course of the catalytic conversion of glycogen." Their research leading to the discovery began during their tenure at Roswell Park (then called the New York State Institute for the Study of Malignant Diseases), from 1922 to 1931.<ref>{{Cite web|title=Gerty Cori - Biographical|url=https://www.nobelprize.org/prizes/medicine/1947/cori-gt/biographical/|url-status=live|access-date=10 May 2021|website=[[Nobel Prize]]}}</ref>
* Children’s Cancer Institute in Australia, Sydney, Australia<ref>{{Cite news|date=November 6, 2015|title=International Team of Researchers Reports Promising Results in Study of Pediatric Neuroblastoma|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201511-international-team-researchers-reports-promising-results-study-pediatric-neuroblastoma|access-date=May 13, 2021}}</ref>
* [[Thomas Dao]] (1921–2009), served as director of the breast surgery department from 1957 to 1988, where he developed [[breast cancer]] treatment alternatives.<ref>Hevesi, Dennis. [https://www.nytimes.com/2009/07/26/health/26dao.html "Dr. Thomas Dao, Expert on Treatment of Breast Cancer, Dies at 88"], ''[[The New York Times]]'', July 25, 2009. Accessed July 26, 2009.</ref>
* Institute of Materia Medica of Nanyang Normal University, China
* [[Jagiellonian University]] (JU), Kraków, Poland<ref>{{Cite news|date=November 15, 2018|title=Roswell Park Establishes Partnership with Jagiellonian University in Krakow, Poland|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201811-roswell-park-establishes-partnership-jagiellonian-university-krakow-poland|access-date=May 13, 2021}}</ref>
* [[King Fahad Specialist Hospital Dammam|King Fahad Specialist Hospital]], Dammam, Saudi Arabia<ref>{{Cite news|date=November 17, 2010|title=Roswell Park Comprehensive Cancer Center to Train Clinical Staff from Saudi Hospital in Cancer Care|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201011-roswell-park-comprehensive-cancer-center-train-clinical-staff-saudi-hospital-cancer|access-date=May 12, 2021}}</ref>
* Lakeshore Cancer Center (LCC), Laos, Nigeria<ref>{{Cite news|date=June 30, 2015|title=Intercontinental Oncology Partnership Brings Access to Specialized Cancer Care to Nigeria|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201506-intercontinental-oncology-partnership-brings-access-specialized-cancer-care-nigeria|access-date=May 12, 2021}}</ref>
* Maccabi Healthcare Services and University of Haifa, Israel<ref>{{Cite news|date=July 2, 2019|title=On Solidarity Trip to Israel, Governor Cuomo Announces Establishment of Joint Program Uniting U.S. and Israeli Cancer Experts in Effort to Research and Develop New Cancer Therapies and Precision Diagnostic Tools|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201907-solidarity-trip-israel-governor-cuomo-announces-establishment-joint-program-uniting-us-israeli|access-date=May 13, 2021}}</ref>
* National Research Center for Hematology, Moscow, Russia
* Pecs Medical University, Pecs, Hungary
* [[Queen Mary University of London]], United Kingdom
* [[Semmelweis University]], Budapest, Hungary
* University of Szeged Medical School, Szeged, Hungary
* [[University of Waterloo]], Canada<ref>{{Cite news|date=April 4, 2021|title=Roswell Park Designated Scientific Lead for Ongoing Population Assessment of Tobacco and Health (PATH) Study|publisher=Roswell Park Comprehensive Cancer Center|url=https://www.roswellpark.org/newsroom/201604-roswell-park-designated-scientific-lead-ongoing-population-assessment-tobacco-health-path-study|access-date=May 13, 2021}}</ref>


==See also==
==See also==
{{Portal|New York|Medicine}}
* [[Erie County Medical Center]]
* [[Erie County Medical Center]]
* [[Nassau University Medical Center]]
* [[Nassau University Medical Center]]
Line 132: Line 235:


== External links ==
== External links ==
* [http://www.roswellpark.org/ Roswell Park Comprehensive Cancer Center homepage]
* [https://www.roswellpark.org/ Roswell Park Comprehensive Cancer Center]
* [http://www.roswellpark.org/giving/ Roswell Park Alliance Foundation]
* [http://www.roswellpark.org/giving/ Roswell Park Alliance Foundation]
* [https://bnmc.org/ Buffalo Niagara Medical Campus]
* [https://bnmc.org/ Buffalo Niagara Medical Campus]
Line 141: Line 244:
* [http://www.teamcure.com Team Cure Challenge]
* [http://www.teamcure.com Team Cure Challenge]
* [http://www.yroswell.com/ Yroswell for Generation Y]
* [http://www.yroswell.com/ Yroswell for Generation Y]
* [http://www.ovariancancer.com Familial Ovarian Cancer Registry]
* [https://www.roswellpark.org/ovarian-cancer-registry Familial Ovarian Cancer Registry]
* [http://cancerconnect.com/roswellpark/ Roswell Park Cancer Connect community site]
* [http://cancerconnect.com/roswellpark/ Roswell Park Cancer Connect community site]


{{NYStateOfficers}}
{{New York state agencies}}
{{New York state public-benefit corporations}}
{{New York state public-benefit corporations}}



Revision as of 20:04, 13 May 2021

Roswell Park Comprehensive Cancer Center
National Comprehensive Cancer Network
Map
Geography
LocationBuffalo, Erie County, New York, United States
Coordinates42°53′50″N 78°52′01″W / 42.897185°N 78.866852°W / 42.897185; -78.866852
Organization
Care systemMedicare
TypeSpecialist
Affiliated universityUniversity at Buffalo, the State University of New York
Services
StandardsNCI-designated Cancer Center
Beds133 (licensed)
SpecialityOncology, Teaching hospital
History
Former name(s)The Pathological Laboratory of the University of Buffalo (1898 - 1899)
The Gratwick Research Laboratory (1900 - 1911)
The State Institute for the Study of Malignant Disease (1912-1945)
Roswell Park Memorial Institute (1946 - 1991)
Roswell Park Cancer Institute (1992 - 2017)
Opened1898; 126 years ago (1898)
Links
Websitewww.roswellpark.org
ListsHospitals in New York State
Other linksList of NYS Public Benefit Corporations

Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research.[1][2][3] The center, which conducts clinical research on cancer as well as the development new drugs, provides advanced treatment for all forms of adult and pediatric cancer, and serves as a member of the National Comprehensive Cancer Network. Roswell Park Comprehensive Cancer Center is currently the only upstate New York facility to hold the National Cancer Institute designation of "comprehensive cancer center".[4]

The Roswell Park campus, spread out in 15 separate buildings of approximately two million square feet, occupies 28 acres (11 ha) on the 100-acre (40 ha) Buffalo Niagara Medical Campus (BNMC) in downtown Buffalo, and includes 1,500,000 square feet (140,000 m2) of space equally distributed between clinical programs and research/education functions. A separate hospital building, completed in 1998, houses a diagnostic and treatment center. The campus also includes a medical research complex as well as research and education focused spaces.

History

In 1898, Roswell Park Comprehensive Cancer Center was established by Roswell Park, who was a professor of surgery at the University of Buffalo School of Medicine.[5] Park said that "Only through a deliberate well-planned, combined attack from various directions by means fitted for such work could real advances be made and further the relationship of laboratory work, clinical study and education must be closely associated."[5]

Research started in three rooms in the University of Buffalo School of Medicine but not long thereafter, it outgrew the rooms. Seeing the importance of dedicated cancer research, select Buffalo citizens donated funds to purchase land and construct a new building. The largest contributor was Mrs. William Gratwick (wife of William H. Gratwick, the founder of Gratwick, Smith & Fryer Lumber Co.), who donated $25,000. The Gratwick Research Laboratory of the University of Buffalo was constructed in 1901 and was located at High and Elm streets.[6]

Park wrote books, gave lectures, and was the administrator at the cancer research center. In 1904, Park stepped down and Harvey R. Gaylord took over as the center's second director. Park remained as the chairman of the board of trustees.[7]

Notable facts

  • Founded in 1898 as the world's first institute devoted exclusively to cancer research[8]
  • Dr. Gerty Cori was the first woman to receive the Nobel Prize in Physiology or Medicine.[9]
  • The center's first female leader, Candace S. Johnson, PhD, was named President & CEO in February 2015.[10]
  • First example of direct government interest (New York State) in cancer research
  • Leads New York State in the number of robotic cystectomies performed[11]
  • Established one of the nation's first long-term survivors clinics for childhood cancer patients[12]
  • Member of international team of scientists who produced the landmark studies of the Human Genome project

Discoveries and advancements in cancer care

Discovery of how the human body converts glucose to glycogen

Gerty Cori and Carl Cori jointly won the 1947 Nobel Prize in Physiology or Medicine for their discovery of the way in which the body converts glucose to glycogen.

Drs. Gerty and Carl Cori jointly won the 1947 Nobel Prize in Physiology or Medicine, "for their discovery of the course of the catalytic conversion of glycogen."[13] Their research leading to the discovery began during their tenure at Roswell Park (then called the New York State Institute for the Study of Malignant Diseases), from 1922 to 1931.[14]

Alternative breast cancer treatments

Thomas Dao (1921–2009), served as director of the breast surgery department from 1957 to 1988, where he developed breast cancer treatment alternatives.[15]

Development of photodynamic therapy

In 1975, Dr. Thomas Dougherty successfully treated preclinical models of cancer using photodynamic therapy (PDT) techniques for the first time.[16][17] In 1978, he conducted the first PDT clinical trial.[18][19] Today, PDT is an FDA-approved method for treating specific kinds of cancer, and is used around the world.

Discovery of PSA

Research resulting in the discovery of the prostate-specific antigen (PSA) was led by Dr. T. Ming Chu in the 1970s.[20] His team subsequently developed a way to detect the PSA protein in blood as a simple diagnostic test.[21] Since its FDA approvals in 1986 and 1994, an estimated one billion PSA tests have been given.

Research on 5-fluorouracil + leucovorin

Biochemist Marie Hakala, PhD[22][23] first observed that 5-fluorouracil becomes more effective in treating cancer cells when calcium leucovorin is added.[24][25] This discovery paved the way for the development of 5-FU + leucovorin therapy, which was for many years the gold standard of chemotherapy for colorectal cancer.

Organization

Mission

The mission of Roswell Park is to "eliminate cancer's grip on humanity by unlocking its secrets through personalized approaches and unleashing the healing power of hope"[26].

Structure

The Roswell Park Cancer Institute Corporation, which is the name of the New York State public-benefit corporation that operates the center, is guided by a 14-member board of directors (which has its own staff).[27] The management team is headed by President and CEO Candace S. Johnson, PhD, who reports to the board.[28] In 2017, it had operating expenses of $722.45 million, an outstanding debt of $189.67 million, and a staffing level of 2,919 people.[29]

Reputation

Roswell Park Comprehensive Cancer Center has received numerous accolades for the quality of healthcare provided.

Accreditation

Patient care

Scott Bieler Clinical Sciences Center

Roswell Park provides comprehensive care for a wide range of cancers.[47]

Specialized treatments

Roswell Park offers specialized treatments, services and therapies to treat cancer, as well as services to support patients undergoing cancer treatment.[48][49]

Collaborations

CIMAvax

Roswell Park was the first American institution to receive FDA permission to conduct clinical trials of CIMAvax, a Cuban medical therapy developed by Centro de Immunologica Molecular, La Habana, Cuba.[50][51]

Ovarian Cancer SPORE

The Ovarian Cancer SPORE is a collaboration between Roswell Park and University of Pittsburgh Cancer Institute (UPCI). The SPORE project includes multiple research projects, core supportive structures, and career development programs.[52]

Cancer Registries

Stacey Scott Lung Cancer Registry

Together with the British Columbia Cancer Agency, Vancouver, Canada and Vrije Universiteit, Amsterdam, The Netherlands, Roswell Park manages the Stacey Scott Lung Cancer Registry.[53]

Familial Ovarian Cancer Registry

Founded in 1990 by Dr. Steven Piver, the Familial Ovarian Cancer Registry houses information relating to family history and lifestyle of patients and families with histories of ovarian cancer.[54][55]

Research and training collaborations

Roswell Park collaborates with institutions around the world to strengthen cancer training and research programs.[56]

See also

References

  1. ^ Rusch, Harold P (1985). "Beginnings of Cancer Research Centers in the United States". Journal of the National Cancer Institute. 74 (2): 391–403. doi:10.1093/jnci/74.2.391. The first center in the United States devoted specifically for research on cancer was founded by Dr. Roswell Park in 1898. Dr. Park, a professor of surgery at the University of Buffalo (Buffalo, NY), with Mr. Edward Butler, publisher of the Buffalo Evening News, in 1897 persuaded the legislators of New York State to appropriate $7,500 for cancer research.
  2. ^ "Roswell Park celebrates 120 years with time capsule". WGRZ. April 25, 2018. Retrieved May 10, 2021.
  3. ^ "1898-1950". Roswell Park Comprehensive Cancer Center. Retrieved May 10, 2021.
  4. ^ "Roswell Park Comprehensive Cancer Center". National Cancer Institute. 2019. Retrieved May 11, 2021.{{cite web}}: CS1 maint: url-status (link)
  5. ^ a b Mirand, Edwin A (1998). Legacy And History Of Roswell Park Cancer Institute, 1898-1998. Virginia Beach, VA: The Donning Company. p. 9. ISBN 9781578642816.
  6. ^ Mirand, Edwin A (1998). Legacy And History Of Roswell Park Cancer Institute, 1898-1998. Virginia Beach, VA: The Donning Company. p. 16. ISBN 9781578642816.
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