3-chloro-2-hydroxypropyl- N , N , N -trimethylammonium chloride

Structural formula
	Simplified structural formula without stereochemistry
General
Surname	3-chloro-2-hydroxypropyl- N , N , N -trimethylammonium chloride
other names	CHPTAC; QUAT 188, QUAB® 188 ( registered trademark of an aqueous solution ); N - (3-chloro-2-hydroxypropyl) - N , N , N trimethylammonium chloride; ( RS ) -3-chloro-2-hydroxypropyl- N , N , N -trimethylammonium chloride;
Molecular formula	C 6 H 15 Cl 2 NO
Brief description	colorless and odorless combustible solid
External identifiers / databases
EC number	222-048-3
ECHA InfoCard	100.020.045
PubChem	18732
Wikidata	Q223065
properties
Molar mass	188.10 g mol −1
Physical state	firmly
density	1.11 g cm −3 (97.3% purity at 20 ° C)
Melting point	180.5 ° C
Vapor pressure	15 hPa (20 ° C)
solubility	easily in water (835 g l −1 at 20 ° C); soluble in alcohol; insoluble in hydrocarbons and chlorinated hydrocarbons;
Refractive index	1.4541 (20 ° C)
safety instructions
H and P phrases	H: 351-412
	P: 201-202-273-280-308 + 313-501
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

3-chloro-2-hydroxypropyl N , N , N -trimethylammonium chloride (also briefly CHPTAC ) is a chemical compound from the group of quaternary ammonium salts , and organic chlorine compounds .

properties

3-chloro-2-hydroxypropyl- N , N , N -trimethylammonium chloride is a slightly volatile, flammable solid. It is easily soluble in water and its aqueous solution is acidic. The commercial product is an approximately 60% aqueous solution. To protect the compound against hydrolysis , a pH of 3 to 5 must be maintained.

use

3-chloro-2-hydroxypropyl- N , N , N -trimethylammonium chloride is used for the cationization (synthesis of cationic bipolymers ) of cellulose , starch and similar compounds. It also serves to quaternize compounds with hydroxyl , amino and other functional groups .

Individual evidence

↑ QUAB 188 (QUAB) .
↑ ^a ^b ^c ^d ^e ^f ^g Entry on (3-chloro-2-hydroxypropyl) trimethylammonium chloride in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
↑ ^a ^b ^c ^d Toxicological assessment of QUAB 188 (PDF) at the professional association raw materials and chemical industry (BG RCI), accessed on August 22, 2012.
↑ Data sheet 3-chloro-2-hydroxypropyl-N, N, N-trimethylammonium chloride from Sigma-Aldrich , accessed on October 13, 2010 ( PDF ).
↑ Entry on (3-chloro-2-hydroxypropyl) trimethylammonium chloride in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[1] QUAB 188 (QUAB) .

[GESTIS-2] ↑ ^a ^b ^c ^d ^e ^f ^g Entry on (3-chloro-2-hydroxypropyl) trimethylammonium chloride in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .

[bg-3] Toxicological assessment of QUAB 188 (PDF) at the professional association raw materials and chemical industry (BG RCI), accessed on August 22, 2012.

[Sigma-4] Data sheet 3-chloro-2-hydroxypropyl-N, N, N-trimethylammonium chloride from Sigma-Aldrich , accessed on October 13, 2010 ( PDF ).

[CLP_100.020.045-5] Entry on (3-chloro-2-hydroxypropyl) trimethylammonium chloride in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on February 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .