4- tert- butylbenzaldehyde

Structural formula
General
Surname	4-tert-butylbenzaldehyde
other names	p - tert -butylbenzaldehyde
Molecular formula	C 11 H 14 O
Brief description	colorless liquid with a terpene-like, camphor-like, spicy, fruity odor
External identifiers / databases
EC number	213-367-9
ECHA InfoCard	100.012.152
PubChem	70324
Wikidata	Q15725613
properties
Molar mass	162.23 g mol −1
Physical state	liquid
density	0.973 g cm −3 (20 ° C)
Melting point	<−20 ° C
boiling point	244-246 ° C
Vapor pressure	3–4 Pa (20 ° C)
solubility	very heavy in water (133 mg l −1 at 20 ° C)
Refractive index	1.5270 (20 ° C)
safety instructions
H and P phrases	H: 302-317-410
	P: 261-273-342 + 311-501
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

4- tert -Butylbenzaldehyde is a chemical compound from the group of aldehydes .

Extraction and presentation

4- tert -Butylbenzaldehyde can be obtained by oxidizing 4- tert -butyltoluene with hydrogen peroxide in glacial acetic acid , catalyzed by bromide ions in combination with cobalt (II) acetate or cerium (III) acetate .

properties

4- tert -Butylbenzaldehyde is a flammable, hardly inflammable, light- and air-sensitive, colorless liquid with a terpene-like, camphor-like, spicy, fruity odor that is very sparingly soluble in water.

use

4- tert -Butylbenzaldehyde is an important intermediate for the synthesis of drugs, colorants, aromas and fragrances. It is used to manufacture penicillin derivatives with an isoxazolyl partial structure.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on 4-tert-butylbenzaldehyde in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .
↑ ^a ^b ^c data sheet 4-tert-butylbenzaldehyde, 97% from Sigma-Aldrich , accessed on January 27, 2019 ( PDF ).
^ CRC Handbook of Chemistry and Physics, 95th Edition . CRC Press, 2014, ISBN 978-1-4822-0868-9 .
^ Leon G. A. van de Water, Arati Kaza, James K. Beattie, Anthony F. Masters, Thomas Maschmeyer: Partial Oxidation of 4- tert -Butyltoluene Catalyzed by Homogeneous Cobalt and Cerium Acetate Catalysts in the Br ^- / H ₂ O ₂ / Acetic Acid System: Insights into Selectivity and Mechanism . In: Chemistry - A European Journal . tape 13 , no. 28 , 2007, pp. 8037-8044 , doi : 10.1002 / chem.200700371 .
↑ Data sheet 4-tert-butylbenzaldehyde, 97% from AlfaAesar, accessed on August 24, 2017 ( PDF )(JavaScript required) .

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on 4-tert-butylbenzaldehyde in the GESTIS substance database of the IFA , accessed on January 9, 2019(JavaScript required) .

[Sigma-2] ta sheet 4-tert-butylbenzaldehyde, 97% from Sigma-Aldrich , accessed on January 27, 2019 ( PDF ).

[3] CRC Handbook of Chemistry and Physics, 95th Edition . CRC Press, 2014, ISBN 978-1-4822-0868-9 .

[4] Leon G. A. van de Water, Arati Kaza, James K. Beattie, Anthony F. Masters, Thomas Maschmeyer: Partial Oxidation of 4- tert -Butyltoluene Catalyzed by Homogeneous Cobalt and Cerium Acetate Catalysts in the Br ^- / H ₂ O ₂ / Acetic Acid System: Insights into Selectivity and Mechanism . In: Chemistry - A European Journal . tape 13 , no. 28 , 2007, pp. 8037-8044 , doi : 10.1002 / chem.200700371 .

[Alfa-5] Data sheet 4-tert-butylbenzaldehyde, 97% from AlfaAesar, accessed on August 24, 2017 ( PDF )(JavaScript required) .