3,4-dimethoxyacetophenone
| Structural formula | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|||||||||||||||||||
| General | |||||||||||||||||||
| Surname | 3,4-dimethoxyacetophenone | ||||||||||||||||||
| other names |
|
||||||||||||||||||
| Molecular formula | C 10 H 12 O 3 | ||||||||||||||||||
| External identifiers / databases | |||||||||||||||||||
|
|||||||||||||||||||
| properties | |||||||||||||||||||
| Molar mass | 180.20 g mol −1 | ||||||||||||||||||
| Physical state |
firmly |
||||||||||||||||||
| Melting point |
51 ° C |
||||||||||||||||||
| boiling point |
286-288 ° C |
||||||||||||||||||
| solubility |
soluble in hot water, ethanol, diethyl ether, chloroform and benzene |
||||||||||||||||||
| safety instructions | |||||||||||||||||||
|
|||||||||||||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||||||||
3,4-Dimethoxyacetophenone ( Acetoveratrone , 4-Acetylveratrol ) is an aromatic compound that is derived from both acetophenone and veratrole (1,2-dimethoxybenzene). The structure consists of a benzene ring with an attached acetyl group (-COCH 3 ) and two methoxy groups (-OCH 3 ) as substituents .
In Erich Neitzel's work, the analogy of name choice for the derivatives of acetovanillion is used, e.g. For example : Acetoveratrone , derived from Veratrum aldehyde , and Acetoprotocatechon ( 3,4-dihydroxyacetophenone , derived from Protocatechu aldehyde ).
presentation
It is prepared from veratrole and acetyl chloride by means of Friedel-Crafts acylation .
Individual evidence
- ↑ a b CRC Handbook of Tables for Organic Compound Identification , Third Edition, 1984, ISBN 0-8493-0303-6 , p. 174, no. 55.
- ↑ a b Erich Neitzel: "Ueber Derivate des Acetovanillons", in: Reports of the German Chemical Society , 1891 , 24 (2), pp. 2863-2868; doi: 10.1002 / cber.189102402111 .
- ↑ a b Data sheet 3,4-Dimethoxyacetophenone (PDF) from Merck , accessed on May 22, 2017.
- ↑ Erich Neitzel: "Das Acetovanillon und seine Derivate" (Diss.), Berlin 1890, pressure from. Thormann & Goetsch, 40 pages + 2 pages
- ^ Association of authors: Organikum , 19th edition, Johann Ambrosius Barth, Leipzig · Berlin · Heidelberg 1993, ISBN 3-335-00343-8 , p. 341.
Web links
- Entry to 3,4-Dimethoxyacetophenone . In: P. J. Linstrom, W. G. Mallard (Eds.): NIST Chemistry WebBook, NIST Standard Reference Database Number 69 . National Institute of Standards and Technology , Gaithersburg MD, accessed November 17, 2012.