Acid Orange 36

Structural formula
General
Surname	Acid Orange 36
other names	Sodium 3 - [(4-anilinophenyl) diazenyl] benzenesulfonate ( IUPAC ); Acid Yellow 36; Tropaolin G.; Victoria Yellow;
Molecular formula	C 18 H 14 N 3 NaO 3 S
Brief description	orange-red powder
External identifiers / databases
EC number	209-608-2
ECHA InfoCard	100.008.736
PubChem	3935589
ChemSpider	23621349
Wikidata	Q27159458
properties
Molar mass	375.37 g mol −1
Physical state	firmly
Melting point	> 250 ° C
solubility	easily in water and ethanol ; moderate in benzene and diethyl ether ; low in acetone and xylene ;
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 317
	P: 280
Toxicological data	5000 mg kg −1 ( LD 50 , rat , oral ) ; 1000 mg kg −1 ( LD 50 , mouse , ip ) ; 200 mg kg −1 ( LD 50 , mouse , iv ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

CI Acid Orange 36 (common name metanil yellow) is an azo dye and indicator that is used todeterminethe pH value . Its transition point is between pH 1.2 and 2.3, with the color changing from red to yellow. It is sometimes used as a food color ,but is not approvedfor this use in the EU . Acid Orange 36 causes hepatotoxic effectsin laboratory tests, for example in rats.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f RW Sabnis: Handbook of Acid-Base Indicators . CRC Press, Boca Raton 2007, ISBN 978-0-8493-8219-2 , pp. 219 ( limited preview in Google Book search).
↑ ^a ^b ^c ^d ^e data sheet Metanil Yellow from Sigma-Aldrich , accessed on January 28, 2017 ( PDF ).
↑ ^a ^b Beenam Saxena, Shiv Sharma: Food Color Induced Hepatotoxicity in Swiss Albino Rats, Rattus norvegicus . In: Toxicology International . tape 22 , no. 1 , 2015, p. 152–157 , doi : 10.4103 / 0971-6580.172286 , PMC 4721164 (free full text).
^ Abdulrahman L. Al-Malki, Ahmed Amir Radwan Sayed: Bees' Honey Attenuation of Metanil-Yellow-Induced Hepatotoxicity in Rats . In: Evidence-based Complementary and Alternative Medicine . tape 2013 , 2013, doi : 10.1155 / 2013/614580 , PMC 3684022 (free full text).

[sabnis-1] ↑ ^a ^b ^c ^d ^e ^f RW Sabnis: Handbook of Acid-Base Indicators . CRC Press, Boca Raton 2007, ISBN 978-0-8493-8219-2 , pp. 219 ( limited preview in Google Book search).

[SIGMA-2] ↑ ^a ^b ^c ^d ^e data sheet Metanil Yellow from Sigma-Aldrich , accessed on January 28, 2017 ( PDF ).

[sharma-3] Beenam Saxena, Shiv Sharma: Food Color Induced Hepatotoxicity in Swiss Albino Rats, Rattus norvegicus . In: Toxicology International . tape 22 , no. 1 , 2015, p. 152–157 , doi : 10.4103 / 0971-6580.172286 , PMC 4721164 (free full text).

[abdulraman-4] Abdulrahman L. Al-Malki, Ahmed Amir Radwan Sayed: Bees' Honey Attenuation of Metanil-Yellow-Induced Hepatotoxicity in Rats . In: Evidence-based Complementary and Alternative Medicine . tape 2013 , 2013, doi : 10.1155 / 2013/614580 , PMC 3684022 (free full text).