Biguanide

Structural formula
General
Surname	Biguanide
other names	Guanylguanidine Amidoguanidine 2-carbamimidoylguanidine
Molecular formula	C 2 H 7 N 5
Brief description	colorless solid
External identifiers / databases
CAS number 56-03-1 2583-53-1 (sulfate) 4761-93-7 (hydrochloride) EC number 200-251-8 ECHA InfoCard 100,000,229 PubChem 5939 ChemSpider 5726 DrugBank DB13100 Wikidata Q142880
properties
Molar mass	101.11 g mol −1
Physical state	firmly
Melting point	130 ° C
solubility	soluble in ethanol practically insoluble in ether, benzene and chloroform
safety instructions
GHS hazard labeling no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Biguanide is a chemical compound . The biguanides used to treat diabetes mellitus are derived from their chemical structure .

Extraction and presentation

Biguanide can be obtained by reacting dicyandiamide with ammonia .

${\displaystyle \mathrm {C_{2}H_{4}N_{4}+NH_{3}\longrightarrow C_{2}H_{7}N_{5}} }$

properties

Biguanide is a colorless, crystalline solid that dissolves in water with a strongly alkaline reaction.

use

The sulfate is used to determine copper and nickel . From the connection guided antidiabetics ( metformin , buformin ), antimalarials ( proguanil ) or virucides ( Moroxydin ) and other drugs (for example, chlorhexidine ab), complexing agents and other chemical compounds.

Individual evidence

1. ↑ ^{a b c d e} Entry on biguanides. In: Römpp Online . Georg Thieme Verlag, accessed on July 3, 2017.
2. ↑ ^{a b} W.LF Armarego: Purification of Laboratory Chemicals . Butterworth-Heinemann, 2017, ISBN 978-0-12-805456-7 , pp. 110 ( limited preview in Google Book search).
3. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
4. ^ Reports of the German Chemical Society . Verlag Chemie, 1889, OCLC 6118701 , p. 334 ( limited preview in Google Book search).