Calcium lactate gluconate

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Structural formula
Structural formula of calcium lactate gluconate
Mixture of calcium lactate (above) and calcium gluconate (below)
General
Surname Calcium lactate gluconate
other names
  • Calcium lactogluconate
  • CLG
  • Calcium lactate gluconate
  • Calcium lactogluconate
  • E  327
  • E  578
Molecular formula Cannot be specified, as a mixture of substances
Brief description

white, odorless solid

External identifiers / databases
CAS number 11116-97-5
EC number 234-359-1
ECHA InfoCard 100.031.223
PubChem 92237
Wikidata Q414151
Drug information
ATC code

A12 AA06

properties
Molar mass 448.40 g mol −1
Physical state

firmly

solubility

good in water (400 g l −1 )

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
no GHS pictograms
H and P phrases H: no H-phrases
P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Calcium lactate gluconate , a double salt of lactic and gluconic acid , is a white, odorless, tasteless, crystalline solid .

properties

The calcium content is between 10% and 13%. The calcium content, like the molar mass, results from the mixing ratio of calcium lactate (13% calcium) to calcium gluconate (9% calcium).

A favorable molar ratio of the two anions (lactate and gluconate) causes a synergistic increase in solubility; Thus, calcium lactate gluconate with 400 g / L has the second highest solubility (after calcium chloride ) among all calcium salts and at the same time has a very good bioavailability of the calcium it contains . For comparison: the solubility of calcium lactate is 66 g / L, that of calcium gluconate 35 g / L.

use

In addition to the long-known positive influence of calcium on bone density (see osteoporosis ), recent studies show that with an adequate calcium intake, the risk of overweight and obesity also decreases. For these reasons, calcium lactate gluconate is used for calcium fortification as an additive for food and dietary supplements ( functional food ). It is also used in pharmaceuticals and animal feed . For example, it is used in effervescent tablets as a source of calcium.

literature

Web links

Individual evidence

  1. Entry on E 327: Calcium lactate in the European database for food additives, accessed on June 27, 2020.
  2. Entry on E 578: Calcium gluconate in the European database for food additives, accessed on June 27, 2020.
  3. a b c Data sheet calcium gluconate monohydrate (PDF) from Merck , accessed on June 25, 2017.
  4. Gerhard Gerstner: Calcium Lactate Gluconate - the innovative solution for extra calcium . In: Innovations in Food Technology . Vol. 3, 2002, pp. 2-3 ( PDF ).