Cathine

from Wikipedia, the free encyclopedia
Structural formula
Structure of cathine
General
Non-proprietary name Cathine
other names
  • Pseudonorephedrine
  • Norpseudoephedrine
  • β-hydroxyamphetamine
  • (+) - (1 S , 2 S ) -2-amino-1-phenylpropan-1-ol
Molecular formula C 9 H 13 NO
External identifiers / databases
CAS number
EC number 207-754-1
ECHA InfoCard 100.007.050
PubChem 441457
ChemSpider 390189
DrugBank DB01486
Wikidata Q423797
Drug information
ATC code

A08 AA07

Drug class

stimulant

properties
Molar mass 151.21 g · mol -1
Physical state

firmly

Melting point

174-176 ° C

solubility

poorly in water (20 g · l −1 at 20 °), soluble in hydrochloric acid and ethanol

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
06 - Toxic or very toxic

danger

H and P phrases H: 301-315-319-335
P: 261-301 + 310-305 + 351 + 338
Toxicological data

161 mg kg −1 ( LD 50 ,  mouse ,  ip )

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cathine ( INN ), also norpseudoephedrine , pseudonorephedrine , β-hydroxyamphetamine, is an alkaloid , chemically an amphetamine , and is one of the stimulants . Cathine is one of the alkaloids in the drug Kath , which is mainly found in the high altitudes of East African countries and on the Arabian Peninsula . The active ingredient is obtained, among other things, from the leaves of the Kath shrub that occurs, and partly from the tips of branches with leaves.

application

The cath shrub contains cathine.

Medicines containing cathine are sold as anorectics (appetite suppressants). These require a prescription and may only be used for a few weeks.

Vita-Slim drops and X-112 were withdrawn from the European market as medicinal products . After the name change from norpseudoephedrine to cathine, a drug was produced under the name ALVALIN solution .

The fabric is on the prohibited list of the IOC , the limit is about 5 ug / ml in urine.

Legal status

In Germany, cathine is classified as a marketable and prescription narcotic drug by the Narcotics Act, handling it without a permit or prescription is a criminal offense.

Trade names

Alvaline

See also

Individual evidence

  1. ↑ a b c d e Cathin data sheet from Sigma-Aldrich , accessed on March 16, 2011 ( PDF ).Template: Sigma-Aldrich / name not given
  2. ↑ Stefan W Toennes, Sebastian Harder, 1 Markus Schramm, Constanze Niess, and Gerold F Kauert : "Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves", Institute of Forensic Toxicology, University of Frankfurt, PMC 1884326 (free full text ).