Corticoviridae

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Corticoviridae
Corticovirus.png

Structure of the phage PM2

Systematics
Classification : Viruses
Area : Varidnaviria
Empire : Bamfordvirae
Phylum : Preplasmiviricota
Class : Tectiliviricetes
Order : Vinavirales
Family : Corticoviridae
Genre : Corticovirus
Type : Pseudoalteromonas phage PM2
Taxonomic characteristics
Genome : dsDNA circular
Baltimore : Group 1
Symmetry : icosahedral T = 21
Cover : no
Scientific name
Corticovirus
Left

The virus family Corticoviridae ( Latin cortex , bark, crust ) comprises only one monotypic genus corticovirus of bacteriophages . The only so far (as of March 2019) by the International Committee on Taxonomy of Viruses confirmed (ICTV) species pseudoalteromonas virus PM2 (also pseudoalteromonas phage PM2 , PM2 phage , Alteromonas phage PM2 called) a circular, double-stranded DNA - genome and about 56 nm in diameter, unenveloped icosahedral capsid .

construction

The capsomers are made up of trimers of the capsid protein P2; At the corners of the icosahedral structure there are projections ( spikes ) that are formed by the virus protein P1. Inside (!) The capsid there is a lipid membrane vesicle that consists of virus proteins and the lipid membrane of the host bacterium. The PM2 phage has this inner membrane vesicle in common with the Tectiviridae , but the PM2 phage does not use it to inject DNA into the host bacterium.

Genome

The circular genome is packaged in a highly twisted ( supercoiled ) form within the membrane vesicle. The double-stranded DNA is 10,079 bp in size and codes for nine structural proteins (P1-9), five non-structural proteins (P12-16) and seven gene products of unknown function.

Hosts

So far, two marine bacterial species, Pseudoalteromonas BAL-31 and ER72M2 , have been identified as hosts for the PM2 phage.

Systematics

The National Center for Biotechnology Information (NCBI) names other candidates in addition to the ICTV-confirmed species:

  • Genus corticovirus
  • Species Pseudoalteromonas virus Cr39582 ( Pseudoalteromonas phage Cr39582 )
  • Species Pseudoalteromonas virus PM2 (type)
  • Species " Pseudoalteromonas phage GXT1010 " (proposed)

literature

  • RT Espejo, ES Canelo: Properties of bacteriophage PM2: A lipid-containing bacterial virus . Virology (1968) 34, pp. 738-747
  • HM Kivelä, N. Kalkkinnen, DH Bamford: Bacteriophage PM2 has a protein capsid surrounding a spherical lipid-protein core . Journal of Virology (2002) 76, pp. 8169-8178
  • CM Fauquet, MA Mayo et al .: Eighth Report of the International Committee on Taxonomy of Viruses , London, San Diego, 2004
  • David M. Knipe, Peter M. Howley, et al . (Ed.): Fields' Virology, 4th Edition, Philadelphia 2001

Web links

Individual evidence

  1. a b c d e ICTV: ICTV Taxonomy history: Pseudoalteromonas virus Cr39582 , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
  2. NCBI: Pseudoalteromonas phage GXT1010 (species)