David Ho

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David Ho, 2005

David Da-i Ho (何大一, pinyin : Hé Dàyī) (born November 3, 1952 in Taichung ) is an American AIDS researcher of Taiwanese descent. He is known for his use of protease inhibitors to fight HIV .


Ho was in 1952 in Taichung ( Taiwan born). At the age of 12 he moved with his mother Sonia to live with his father Paul Ho, a soldier and engineer, in Los Angeles in the United States , where he grew up in Los Angeles. In 1974 he obtained a Bachelor of Science degree from the California Institute of Technology with very good grades and received his doctorate four years later from the Harvard-MIT Division of Health Sciences and Technology. He worked in internal medicine and infectious diseases at UCLA (1978–1982) and Massachusetts General Hospital (1982–1985). During an internship at Cedars Sinai Medical Center in Los Angeles in 1981, he came into contact with the first reports of AIDS. Since then he has been working in AIDS research. He was one of the first scientists to realize that AIDS is caused by a virus .

In addition to a large number of publications on the subject, he is perhaps best known for his explanation of the dynamic replication of HI viruses in infected individuals. This understanding brought Ho and his team to the point where antiretroviral therapies were combined with the use of protease inhibitors, resulting in a dramatic reduction in AIDS-related deaths in developing countries.

He also developed the method of trying to kill HIV with "cocktails". He theorized that mixing protease inhibitors with other HIV drugs was a better way forward.

In 1996 he was named Person of the Year by Time magazine . He was also selected to be a member of the American Academy of Arts and Sciences (1997), Academia Sinica, and the Institute of Medicine of the National Academy of Sciences . In 2001 he was honored with the Presidential Citizens Medal , the second highest civil honor in the USA. In 2013 he received the Prince Mahidol Prize .

He is currently Professor and Scientific Director at the Aaron Diamond AIDS Research Center at Rockefeller University in New York and is working with his team on a vaccine against AIDS.

Single receipts

  1. DD Ho, AU Neumann u. a .: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. In: Nature . Volume 373, Number 6510, January 1995, pp. 123-126, doi : 10.1038 / 373123a0 , PMID 7816094 .
  2. ^ DD Ho: Time to hit HIV, early and hard. In: The New England Journal of Medicine . Volume 333, Number 7, August 1995, pp. 450-451, doi : 10.1056 / NEJM199508173330710 , PMID 7616996 .

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