Dectaflur

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Structural formula
Structure of Dectaflur
General
Non-proprietary name Dectaflur
other names
  • 9-octadecenylamine hydrofluoride
  • ( E ) -Octadec-9-en-1-amine hydrofluoride
  • ( E ) -Octadec-9-en-1-amine · hydrofluoride
Molecular formula C 18 H 38 FN
External identifiers / databases
CAS number 36505-83-6
PubChem 6436136
Wikidata Q906509
Drug information
ATC code

A01 AA

properties
Molar mass 287.50 g mol −1
Physical state

firmly

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Dectaflur ( INN ) is an active ingredient that is used locally for the prophylaxis of dental caries and periodontitis .

Chemically, it is the hydrofluoride of a long-chain primary amine . Dectaflur belongs to the amine fluoride group .

Manufacturing

Dectaflur, H 3 C– (CH 2 ) 7 CH = CH– (CH 2 ) 7 CH 2 –NH 2  · HF, is produced by reacting equimolar amounts of 9-octadecenylamine with hydrofluoric acid .

toxicology

Like any other substance, fluorides are toxic if used incorrectly. In the event of a permanent overdose, they can be stored in the bones and change their properties. Overdosing in the first few years of life, before the permanent teeth are developed, can lead to dental fluorosis , which is a localized discoloration and weakening of the hard tissue of the teeth. In Germany, amine fluoride-containing pharmaceuticals for dental care require a prescription , with the exception of gels in pack sizes of up to 25 grams, provided that the packaging states that use is restricted to adults and children from the age of 6 and to a single dose per week which corresponds to a fluoride content of up to 7 mg.

Trade names

Combination preparations

Elmex ® gelée (CH, A, D)

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Martin Negwer: Organic-chemical medicines and their synonyma , Akademie-Verlag Berlin, 5th edition, 1978, p. 695.

See also