Desmetryn

Structural formula
General
Surname	Desmetryn
other names	2-Isopropylamino-4-methylamino-5-methylthio-1,3,5-triazine
Molecular formula	C 8 H 15 N 5 S
Brief description	colorless solid
External identifiers / databases
EC number	213-800-1
ECHA InfoCard	100.012.546
PubChem	13904
Wikidata	Q3024532
properties
Molar mass	213.31 g mol −1
Physical state	firmly
density	1.172 g cm −3
Melting point	84-86 ° C
boiling point	339 ° C (at 984 hPa )
solubility	practically insoluble in water (580 mg l −1 at 20 ° C)
safety instructions
H and P phrases	H: 302 + 312-410
	P: 273-280-301 + 312 + 330-302 + 352 + 310
Toxicological data	1390 mg kg −1 ( LD 50 , rat , oral ) ; > 1000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Desmetryn is a chemical compound from the group of triazines , more precisely the methylthiotriazines.

Extraction and presentation

Desmetryn can be obtained by reacting cyanuric chloride with isopropylamine , methylamine and methyl mercaptan .

properties

Desmetryn is a colorless solid that is practically insoluble in water.

use

Desmetryn is used as a herbicide . It is used to control white goosefoot ( Chenopodium album ), other weeds and some grasses in most types of cabbage, herbs, onions, leeks and conifer seed beds in post-emergence. The effect is based on the inhibition of photosynthesis.

Admission

In the European Union, Desmetryn was not included in Annex I of Directive 91/414 / EEC by Regulation (EC) No. 2076/2002 of November 20, 2002. For this reason, no plant protection products containing Desmetryn may be approved in the member states of the EU.

In Germany, Austria and Switzerland, no pesticides with this active ingredient are permitted. Desmetryn was approved in the FRG between 1971 and 1988 and in the GDR between 1968 and 1994.

The World Health Organization classifies Desmetryn as an outdated pesticide active ingredient.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Entry on Desmetryn in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .
↑ Entry on Desmetryn in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Thomas A. Unger: Pesticide synthesis handbook . 1996, ISBN 978-0-8155-1401-5 , pp. 647 ( limited preview in Google Book search).
↑ Desmetryn data sheet , PESTANAL at Sigma-Aldrich , accessed on November 4, 2016 ( PDF ).
^ Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals, Volume 2 . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 , pp. 641 ( limited preview in Google Book search).
↑ Regulation (EC) No. 2076/2002 (PDF) of the Commission of November 20, 2002
↑ General Directorate Health and Food Safety of the European Commission: Entry on Desmetryn in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 22, 2016.
↑ Peter Brandt: Reports on Plant Protection Products 2009: Active Ingredients In Plant Protection Products ... Springer DE, 2010, ISBN 3-0348-0029-0 , p. 13 ( limited preview in Google Book search).

↑ WHO: Active ingredients believed to be obsolete or discontinued for use as pesticides , in The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009 (PDF; 2.2 MB)

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Entry on Desmetryn in the GESTIS substance database of the IFA , accessed on January 8, 2020(JavaScript required) .

[CLP_100.012.546-2] Entry on Desmetryn in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[Unger-3] Thomas A. Unger: Pesticide synthesis handbook . 1996, ISBN 978-0-8155-1401-5 , pp. 647 ( limited preview in Google Book search).

[Sigma-4] Desmetryn data sheet , PESTANAL at Sigma-Aldrich , accessed on November 4, 2016 ( PDF ).

[Roberts2-5] Terence Robert Roberts, DH Hutson: Metabolic pathways of agrochemicals, Volume 2 . Royal Soc of Chemistry, 1999, ISBN 978-0-85404-499-3 , pp. 641 ( limited preview in Google Book search).

[6] Regulation (EC) No. 2076/2002 (PDF) of the Commission of November 20, 2002

[PSM-7] General Directorate Health and Food Safety of the European Commission: Entry on Desmetryn in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on February 22, 2016.

[Peter_Brandt-8] Peter Brandt: Reports on Plant Protection Products 2009: Active Ingredients In Plant Protection Products ... Springer DE, 2010, ISBN 3-0348-0029-0 , p. 13 ( limited preview in Google Book search).

[9] WHO: Active ingredients believed to be obsolete or discontinued for use as pesticides , in The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009 (PDF; 2.2 MB)