Edward Boyden

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Edward Boyden at the 2013 World Economic Forum

Edward "Ed" S. Boyden III. (Born August 18, 1979 in Plano , Texas ) is an American neuroscientist at the Massachusetts Institute of Technology .

Life

Edward Boyden, the son of a business consultant and biochemist , grew up in Texas with his sister. At the age of twelve, he took part in a state-wide youth science competition in Texas and won first prize. At school he skipped several classes and was already enrolled as a student at the age of 14. He first studied physics at the Texas Academy of Mathematics and Science from 1993 to 1995 . After earning his bachelor's degree, Boyden moved to the Massachusetts Institute of Technology from 1995 to 1999 to study electrical engineering and computer science . There he earned his master's degree in 1999 with a thesis on Quantum Computing: Theory and Implementation . Thereto he graduated from 1999 to 2005 to study neuroscience at Stanford University , where he in 2005 with a dissertation on task-specific neural mechanisms of memory encoding doctorate was.

Boyden is a faculty member of the MIT Media Lab and an associate member of the McGovern Institute for Brain Research .

Edward Boyden is married to neuroscientist Xue Han , whom he met while studying at Stanford University and with whom he has two children. Boyden and Han are not only a couple in their private lives, they also research and publish together.

At the 43rd Annual Meeting of the World Economic Forum from 23 to 27 January 2013 Edward Boyden was among the officially invited scientists.

Act

Edward Boyden became known for his work on optogenetics . In this technology, a light-sensitive ion channel such as channelrhodopsin (ChR2) is genetically modified in neurons , which allows neuron activity to be controlled by light. There were earlier efforts by Gero Miesenböck and Boris Zemelman , dating back to 2002, to achieve targeted optical control, which, however, did not include an ion channel activated directly by light. But only the method developed by Karl Deisseroth in 2005 , which was based on channels of transport proteins such as channelrhodopsin that were activated directly by light , proved to be applicable on a larger scale. In this form, optogenetics has been adopted as an auxiliary science by many neuroscientists. It is believed that it also has therapeutic uses. Edward Boyden joined the MIT Media Lab in 2007, where he works on developing new optogenetic tools as well as other technologies for managing brain activity.

Honors and awards (selection)

Fonts (selection)

  • (edited together with T. Knopfel): Optogenetics: Tools for Controlling and Monitoring Neuronal Activity (= Progress in Brain Research, Volume 196), Elsevier , Amsterdam 2012.

Web links

Commons : Edward Boyden  - collection of images, videos and audio files

Individual evidence

  1. a b Short biography on the website of the Grete Landbeck European Brain Research Foundation: Brain Prize; accessed on September 2, 2019.
  2. a b c Elizabeth Landau: Top brain scientist is 'philosopher at heart' of April 4, 2013, p. 4 , on the CNN website.
  3. a b c d CV of Edward Boyden (PDF, 407 kB) at edboyden.org; accessed on April 7, 2018.
  4. Elizabeth Landau: Top brain scientist is 'philosopher at heart' of April 4, 2013, p. 8 , on the CNN homepage
  5. Xue Han and Edward S. Boyden: Multiple-Color Optical Activation, Silencing, and Desynchronization of Neural Activity, with Single-Spike Temporal Resolution , in: PLOS ONE, March 21, 2007
  6. Xue Han, Xiaofeng Quian, Patrick Stern, Amy Chuong and Edward S. Boyden: Informational Lesions: Optical Perturbation of Spike Timing and Neural Synchrony Via Microbial Opsin Gene Fusions , in: Frontiers in Molecular Neuroscience , Volume 2, (2009), p 12.
  7. Xue Han, Xiaofeng Quian, Jacob G. Bernstein, Hui-hui Zhou, Giovanni Talei Franzesi, Patrick Stern, Roderick T. Bronson, Ann M. Graybiel , Robert Desimone and Edward S. Boyden: Millisecond-Timescale Optical Control of Neural Dynamics in the Nonhuman Primate Brain , in: Neuron , Vol. 62, No. 2 (2009), pp. 191-198
  8. MM McCarthy, C. Moore-Kochlacs, X. Gu, Edward S. Boyden, Xue Han and Nancy Kopell : Striatal origin of the pathologic beta oscillations in Parkinson's disease , in: PNAS , Volume 108, No. 28 (2011), Pp. 11620-11625.
  9. Listing Vita Edward Boyden on the website of the World Economic Forum
  10. ^ A b c Edward S. Boyden: The Birth of Optogenetics. An account of the path to realizing tools for controlling brain circuits with light , in: The Scientist Magazine of July 1, 2011
  11. Boris V. Zemelman, Georgia A. Lee, Minna Ng and Gero Miesenböck: Selective Photostimulation of Genetically ChARGed Neurons , in: Neuron, Volume 33.1, January 3, 2002, pp. 15-22
  12. ^ Rewiring the Brain: Inside the New Science of Neuroengineering . In: Wired , March 2, 2009. 
  13. MIT Technology Review: 35 Top Innovators under 35, 2006
  14. Elizabeth A. Thomson, News Office: Two Scientists named to Discover's 'Top 20 Under 40' list. In: news.mit.edu. November 13, 2008, accessed February 22, 2016 .
  15. Previous winners of the IET AF Harvey Research prize. Retrieved September 2, 2019 .
  16. ^ Mo Costandi: An interview with Ed Boyden. Boyden received the inaugural AF Harvey Engineering Prize for his contribution to the development of optogenetics , in: The Guardian, June 23, 2012
  17. ^ List of the award winners on the website of the UNC Neuroscience Center
  18. ^ Past Winners - Gabbay Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved February 13, 2016 .
  19. Book of Members 1780 – present, Chapter B. (PDF; 1.2 MB) In: American Academy of Arts and Sciences (amacad.org). Accessed April 7, 2018 .