Gero Miesenböck
Gero Miesenböck (born July 15, 1965 in Braunau am Inn ) is an Austrian neurophysiologist . He is considered one of the pioneers in the scientific research field of optogenetics .
Life
Miesenböck studied medicine at the University of Innsbruck . It was 1991 sub auspiciis Praesidentis publicae rei with thesis Relationship of triglycerides and high-density lipoprotein metabolism doctorate . From 1992 to 1998 he worked as a postdoctoral fellow with James Rothman at the Memorial Sloan-Kettering Cancer Center in New York City .
In 1999 he received an Assistant Professor ( Assistant Professor ) for Cell Biology and Genetics and for Neuroscience at Cornell University in New York; In 2004 Miesenböck went to Yale University School of Medicine in New Haven , Connecticut as Associate Professor of Cell Biology and Cellular and Molecular Physiology . In 2007 Miesenböck was appointed to the University of Oxford as Waynflete Professor of Physiology . In 2011 he became the founding director of the Center for Neural Circuits and Behavior there .
Act
From 1999 Miesenböck laid the foundations of optogenetics - partly together with Boris V. Zemelman - with the help of which neurons can be selectively activated using light.
Miesenböck deals with neuronal excitation circuits , which he mainly studies on the model organism of Drosophila melanogaster . In doing so, he looks for the elementary excitation circuits that implement processes such as information integration over time, the use of threshold values in decision-making, error signals or information storage. Optogenetic techniques allow certain groups of neurons that are responsible for certain behavior to be activated with a high degree of accuracy , and neuron excitation circuits to be recognized and hypotheses to be tested about their functioning.
Since 2019 the media group Clarivate has counted him among the favorites for a Nobel Prize ( Clarivate Citation Laureates ).
Awards (selection)
- 2008: Member of the European Molecular Biology Organization
- 2009: Bayliss-Starling Prize Lecture
- 2012: InBev-Baillet Latour Health Prize
- 2013: Brain Prize
- 2013: Jacob Heskel Gabbay Award in Biotechnology and Medicine
- 2014: Corresponding member abroad of the Austrian Academy of Sciences
- 2014: Culture Prize of the Province of Upper Austria
- 2015: BBVA Foundation Frontiers of Knowledge Award
- 2015: Fellow of the Royal Society (London)
- 2015: Heinrich Wieland Prize
- 2016: Member ( matriculation number 7693 ) of the Leopoldina - German Academy of Natural Scientists
- 2016: Wilhelm Exner Medal
- 2016: Massry Prize
- 2017: Member of the Academia Europaea
- 2019: Rumford Prize
- 2019: Warren Alpert Foundation Prize
- 2020: Shaw Prize
literature
- Leopoldina Newly Elected Members 2016, Leopoldina, Halle (Saale) 2017, p. 30 ( PDF )
Web links
- Gero Miesenböck and Research Groups> Miesenböck Group at the Center for Neural Circuits and Behavior of the University of Oxford (ox.ac.uk)
- Miesenboeck Group (working group) at the Department of Physiology, Anatomy and Genetics at the University of Oxford (ox.ac.uk)
- CV (PDF; 73 kB) at inbevbailletlatour.com
- List of publications by Gero Miesenböck on the WorldCat.org website
Individual evidence
- ^ Lief Fenno, Ofer Yizhar and Karl Deisseroth : The Development and Application of Optogenetics , in: Annual Review of Neuroscience , Volume 34 (2011), pp. 389-412, here pp. 390 f.
- ^ Edward S. Boyden : The Birth of Optogenetics. An account of the path to realizing tools for controlling brain circuits with light , in: The Scientist Magazine of July 1, 2011
- ↑ BV Zemelman, GA Lee, M. Ng, G. Miesenböck: Selective photostimulation of genetically chARGed neurons. In: Neuron , Volume 33, Number 1, January 2002, pp. 15-22, ISSN 0896-6273 . PMID 11779476 .
- ↑ Boris V. Zemelman, Nasri Nesnan, Georgia A. Lee and Gero Miesenböck: Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons , in: PNAS , Volume 100, No. 3 (2003), p. 1352 -1357.
- ↑ joint patents of Gero Miesenböck and Boris V. Zemelman on the website Justia Patents .
- ^ Austrian physician Miesenböck under Nobel Prize favorites , accessed on December 13, 2019 in Science.apa.at.
- ^ Gero Miesenböck at the Grete Lundbeck European Brain Research Foundation (thebrainprize.org); Retrieved October 6, 2013
- ^ Past Winners - Gabbay Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved February 13, 2016 .
- ↑ State of Upper Austria - state correspondence No. 152 of August 13, 2014. In: land-oberoesterreich.gv.at. August 13, 2014, accessed June 23, 2015 .
- ↑ orf.at - Miesenböck was "Fellow of the Royal Society" . Article dated May 4, 2015, accessed May 4, 2015.
- ↑ Member entry by Gero Miesenböck at the German Academy of Natural Scientists Leopoldina , accessed on July 29, 2016.
- ^ Membership directory: Gero Miesenböck. Academia Europaea, accessed January 3, 2018 .
| personal data | |
|---|---|
| SURNAME | Miesenböck, Gero |
| BRIEF DESCRIPTION | Austrian neurophysiologist |
| DATE OF BIRTH | July 15, 1965 |
| PLACE OF BIRTH | Braunau am Inn |