Karl Deisseroth

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Karl Deisseroth (born November 18, 1971 in Boston , Massachusetts ) is an American psychiatrist , neurobiologist and bio-engineer at Stanford University .

Live and act

Deisseroth earned a bachelor's degree in biochemistry from Harvard University in 1992 . In 1998 he received a Ph.D. from Richard Tsien at Stanford University. in neuroscience and an MD there in 2000 . Until 2004 he worked as an assistant doctor in internal medicine and above all in psychiatry , and he also worked as a postdoctoral fellow with Robert Malenka . In 2006 Deisseroth acquired a specialist in neurology and psychiatry. In 2005 he became Assistant Professor of Bioengineering and Psychiatry at Stanford University, in 2009 Associate Professor , and in 2012 he was given a full professorship. Since 2009 Deisseroth has also been doing research for the Howard Hughes Medical Institute (HHMI). In 2014 he became Foreign Adjunct Professor at the Karolinska Institutet in Stockholm .

Deisseroth is one of the founders of optogenetics . In this method, light-dependent proteins - channelrhodopsins - are expressed in certain nerve cells , which means that these cells can be electrically activated or inactivated in a targeted manner by different colored light in a matter of milliseconds. The method, which has been adopted by thousands of working groups worldwide, results in numerous new approaches to research into neurological and psychiatric diseases and behavior .

From 2010 to 2013, Deisseroth and his research team at Stanford University School of Medicine developed the CLARITY technology ( acronym for: C lear L ipid-exchanged A natomically R igid I maging / immunostaining R igid T issue h Y drogel). Here is postmortem biological tissue using acrylamide based hydrogels made translucent. CLARITY enables high-resolution three-dimensional recordings of the protein and nucleic acid structure of organs, such as the hippocampus or the spinal cord .

Since 2019 the media group Clarivate has counted him among the favorites for a Nobel Prize ( Clarivate Citation Laureates ). According to Google Scholar, Deisseroth has an h-index of 144, and according to the Scopus database it is 126 (as of June 2020).

Awards (selection)

literature

  • Kerri Smith: Method man: Karl Deisseroth is leaving his mark on brain science one technique at a time , in: Nature , Vol 497, 30 May 2013, p. 550

Web links

Individual evidence

  1. ^ Karl Deisseroth CV (as of 2004) at Stanford University (stanford.edu); accessed on August 31, 2012
  2. ^ Website of the Karolinska Institutet , accessed June 30, 2015.
  3. ↑ Karl Deisseroth: Optogenetics , in: Nature Methods , Volume 8 (2011), pp. 26-29
  4. ↑ Kwanghun Chung, Karl Deisseroth et al. "Structural and molecular interrogation of intact biological systems". Nature 497 (2013), pp. 332-337.
  5. ↑ Karl Deisseroth. In: scholar.google.de. Google Scholar, accessed June 3, 2020 .
  6. ↑ Deisseroth, Karl. In: scopus.com. Scopus, accessed June 3, 2020 .
  7. ^ IOM Class of 2010 ( Memento from April 22, 2011 in the Internet Archive ) at the Institute of Medicine (iom.edu); accessed on August 31, 2012
  8. ↑ Zülch Prize 2012 for the founders of optogenetics at the Science Information Service (idw-online.de); accessed on August 31, 2012
  9. ^ Richard Lounsbery Award at the National Academy of Sciences (nasonline.org); accessed on January 4, 2016
  10. ↑ Karl Deisseroth. Grete Lundbeck European Brain Research Foundation (thebrainprize.org), accessed September 15, 2019 .
  11. ^ Member entry of Karl Deisseroth (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on June 7, 2016.
  12. ^ Harvey Prize 2016
personal data
SURNAME Deisseroth, Karl
BRIEF DESCRIPTION American psychiatrist, neurobiologist, and bio-engineer
DATE OF BIRTH 18th November 1971
PLACE OF BIRTH Boston