Falcarinol

Structural formula
	Structural formula of (-) - falcarinol
General
Surname	Falcarinol
other names	(3 R , 9 Z ) -Heptadeca-1,9-dien-4,6-diyne-3-ol ( IUPAC ) ; Carotid toxin; Panaxynol;
Molecular formula	C 17 H 24 O
Brief description	oily liquid
External identifiers / databases
PubChem	5281149
Wikidata	Q413192
properties
Molar mass	244.37 g mol −1
Physical state	liquid
boiling point	115 ° C (2.6 Pa )
safety instructions
GHS hazard labeling ; no classification available
GHS hazard labeling ; no classification available
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Falcarinol is a naturally occurring unsaturated alcohol . It is a chiral alcohol with two carbon triple and two double bonds .

Meaning and effect

The substance that is effective against pests ( pesticide ) is contained, for example, in carrots , red ginseng ( Panax ginseng ), Saposhnikovia divaricata and common ivy and protects the roots of plants from various fungal diseases such as the Mycocentrospora leaf spots caused by Mycocentrospora acerina .

Common ivy contains the natural substance falcarinol.

In a feeding experiment on rats, falcarinol showed a cancer-preventive effect in low doses; in addition, antibacterial , fungicidal and pain-relieving properties as well as inhibition of platelet aggregation were demonstrated. It is poisonous in larger quantities.

Falcarinol can cause allergic reactions and inflammatory skin irritation . For example, when cutting ivy , which has large amounts of natural toxins and the like. a. Contains falcarinol, light protective measures are therefore recommended.

Web links

Commons : Falcarinol - Collection of Images, Videos and Audio Files

Birgit Buchroithner: Why do carrots work against cancer . In: Bild der Wissenschaft , February 9, 2005.

Individual evidence

↑ ^a ^b ^c ^d Entry on Falcarinol. In: Römpp Online . Georg Thieme Verlag, accessed on February 22, 2014.
↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
↑ Morten Kobæk-Larsen, Lars P. Christensen, Werner Vach, Jelmera Ritskes-Hoitinga, Kirsten Brandt: Inhibitory Effects of Feeding with Carrots or (-) - Falcarinol on Development of Azoxymethane-Induced Preneoplastic Lesions in the Rat Colon. In: Journal of Agricultural and Food Chemistry . 53, 2005, pp. 1823-1827, doi : 10.1021 / jf048519s .
^ S. Machado, E. Silva, A. Massa: Occupational allergic contact dermatitis from falcarinol. In: Contact Dermatitis . 47, 2002, pp. 109-125, doi : 10.1034 / j.1600-0536.2002.470210_5.x .

[römpp-1] Entry on Falcarinol. In: Römpp Online . Georg Thieme Verlag, accessed on February 22, 2014.

[NV-2] This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

[3] Morten Kobæk-Larsen, Lars P. Christensen, Werner Vach, Jelmera Ritskes-Hoitinga, Kirsten Brandt: Inhibitory Effects of Feeding with Carrots or (-) - Falcarinol on Development of Azoxymethane-Induced Preneoplastic Lesions in the Rat Colon. In: Journal of Agricultural and Food Chemistry . 53, 2005, pp. 1823-1827, doi : 10.1021 / jf048519s .

[4] S. Machado, E. Silva, A. Massa: Occupational allergic contact dermatitis from falcarinol. In: Contact Dermatitis . 47, 2002, pp. 109-125, doi : 10.1034 / j.1600-0536.2002.470210_5.x .