Fluotrimazole

Structural formula
General
Surname	Fluotrimazole
other names	1- {Diphenyl- [3- (trifluoromethyl) phenyl] methyl} -1,2,4-triazole; Persulon;
Molecular formula	C 22 H 16 F 3 N 3
Brief description	colorless solid
External identifiers / databases
EC number	250-534-5
ECHA InfoCard	100.045.925
PubChem	91600
Wikidata	Q19279671
properties
Molar mass	379.38 g mol −1
Physical state	firmly
Melting point	131-132 ° C
solubility	almost insoluble in water; soluble in cyclohexanone, dichloromethane, isopropanol, toluene;
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: 413
	P: no P-phrases
Toxicological data	> 5000 mg kg −1 ( LD 50 , rat , oral ) ; > 1000 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Fluotrimazole is a chemical compound from the group of triazoles and trifluoromethylphenyls.

Extraction and presentation

Fluotrimazole can be obtained by reacting trifluoromethylbenzotrichloride with benzene and aluminum chloride and then reacting the intermediate product formed with 1,2,4-triazole .

properties

Fluotrimazole is a colorless solid that is insoluble in water.

use

Fluotrimazole is used as a fungicide . The compound acts by inhibiting sterol - biosynthesis . The compound was first mentioned in 1973 and was the first triazole fungicide to be marketed.

Admission

Fluotrimazole is not approved as a crop protection agent in the European Union or Switzerland .

Individual evidence

↑ ^a ^b ^c ^d Entry on Fluotrimazole in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on January 22, 2015.
↑ ^a ^b ^c ^d ^e ^f ^g Fluotrimazole data sheet , PESTANAL from Sigma-Aldrich , accessed on November 3, 2016 ( PDF ).
↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 696 ( limited preview in Google Book search).
^ Fluorine and the Environment: Agrochemicals, Archeology, Green Chemistry ... Elsevier, 2006, ISBN 978-0-08-046561-6 , pp. 132 ( limited preview in Google Book search).
^ Encyclopedia of Agriculture and Food Systems: 5-volume set . Elsevier, 2014, ISBN 0-08-093139-1 , pp. 415 ( limited preview in Google Book search).
^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national directory of plant protection products in Switzerland ; Retrieved June 25, 2016.

[PPDB-1] Entry on Fluotrimazole in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on January 22, 2015.

[Sigma-2] ↑ ^a ^b ^c ^d ^e ^f ^g Fluotrimazole data sheet , PESTANAL from Sigma-Aldrich , accessed on November 3, 2016 ( PDF ).

[Thomas_A._Unger-3] Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 696 ( limited preview in Google Book search).

[NN1-4] Fluorine and the Environment: Agrochemicals, Archeology, Green Chemistry ... Elsevier, 2006, ISBN 978-0-08-046561-6 , pp. 132 ( limited preview in Google Book search).

[NN2-5] Encyclopedia of Agriculture and Food Systems: 5-volume set . Elsevier, 2014, ISBN 0-08-093139-1 , pp. 415 ( limited preview in Google Book search).

[6] Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national directory of plant protection products in Switzerland ; Retrieved June 25, 2016.