Flupyradifuron

Structural formula
General
Surname	Flupyradifuron
other names	4 - [(6-chloro-3-pyridylmethyl) (2,2-difluoroethyl) amino] furan-2 (5 H ) -one
Molecular formula	C 12 H 11 ClF 2 N 2 O 2
Brief description	white powder with a faint odor
External identifiers / databases
EC number	804-373-8
ECHA InfoCard	100.231.094
PubChem	16752772
Wikidata	Q21050747
properties
Molar mass	288.68 g mol −1
Physical state	firmly
density	1.43 g cm −3
Melting point	69 ° C
boiling point	decomposes above 270 ° C
solubility	sparingly soluble in water (3.2 g l −1 at 20 ° C)
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 302
	P: no P-phrases
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Flupyradifuron is a chemical compound from the butenolide group that is effective as an insecticide .

Like the neonicotinoids, flupyradifuron is a nAChR agonist that permanently opens the nicotinic acetylcholine receptors and thus disrupts chemical signal transmission. It is dangerous to bees, but less so than most other neonicotinoids.

The compound was developed at Bayer CropScience based on the natural substance Stemofolin , an alkaloid from Stemona japonica .

Admission

In some EU countries, including Germany, plant protection products with this active ingredient (trade name Sivanto ) have been approved since November 2015, but not in Austria or Switzerland.

After winning a legal dispute, the Federal Office for Consumer Protection and Food Safety had to provide the Environmental Institute in Munich with information on whether there were any approval applications for the new insecticide flupyradifuron. Result: There are currently 5 applications for the approval of pesticide mixtures with flupyradifuron.

Australia is also preparing for approval.

Individual evidence

↑ ^a ^b ^c ^d ^e Entry on flupyradifurone in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on July 30, 2015.
↑ ^a ^b Flupyradifurone data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

↑ Ralf Nauen, Peter Jeschke, Robert Velten, Michael E Beck, Ulrich Ebbinghaus-Kintscher, Wolfgang Thielert, Katharina Wölfel, Matthias Haas, Klaus Kunz, Georg Raupach: Flupyradifurone: a brief profile of a new butenolide insecticide . In: Pest Management Science . tape 71 , no. 6 , January 1, 2014, doi : 10.1002 / ps.3932 ( PDF ).

↑ Insect mortality : Replacement insecticides also damage bees considerably. In: goettinger-tageblatt.de . April 10, 2019, accessed May 2, 2019 .

↑ Flupyradifurone: A new insecticide or just another neonicotinoid? , February 5, 2015.

↑ Targeted against sucking insects .

↑ Directorate-General for Health and Food Safety of the European Commission: Entry on flupyradifurone in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.

↑ Christine Vogt: After a successful lawsuit: Authority provides information on insect poisons In: Umweltinstitut.org , June 25, 2018, accessed on June 27, 2018.

[ppdb-1] Entry on flupyradifurone in the Pesticide Properties DataBase (PPDB) of the University of Hertfordshire , accessed on July 30, 2015.

[Sigma-2] Flupyradifurone data sheet from Sigma-Aldrich , accessed on May 21, 2017 ( PDF ).

[3] Ralf Nauen, Peter Jeschke, Robert Velten, Michael E Beck, Ulrich Ebbinghaus-Kintscher, Wolfgang Thielert, Katharina Wölfel, Matthias Haas, Klaus Kunz, Georg Raupach: Flupyradifurone: a brief profile of a new butenolide insecticide . In: Pest Management Science . tape 71 , no. 6 , January 1, 2014, doi : 10.1002 / ps.3932 ( PDF ).

[4] Insect mortality : Replacement insecticides also damage bees considerably. In: goettinger-tageblatt.de . April 10, 2019, accessed May 2, 2019 .

[5] Flupyradifurone: A new insecticide or just another neonicotinoid? , February 5, 2015.

[6] Targeted against sucking insects .

[7] Directorate-General for Health and Food Safety of the European Commission: Entry on flupyradifurone in the EU pesticide database; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on December 6, 2019.

[8] Christine Vogt: After a successful lawsuit: Authority provides information on insect poisons In: Umweltinstitut.org , June 25, 2018, accessed on June 27, 2018.