Gerald D. Fischbach

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Gerald D. Fischbach (2011)

Gerald David "Gerry" Fischbach (born November 15, 1938 in New Rochelle , New York ) is an American neuroscientist. He dealt with the formation of synapses at the molecular level.

Fischbach earned a bachelor's degree from Colgate University in 1960 and an MD from Cornell University in 1965 as a medical degree. After research positions at the National Institute of Neurological Diseases and Stroke and at the National Institute of Child Health , Fischbach received his first professorship (associate professor) in pharmacology at Harvard University in 1973 , and a full professorship in 1978. In 1981 he moved to Washington University in St. Louis School of Medicine , where he took over the chair of neurobiology . In 1990 he moved to the same position at Harvard Medical School and also became a Fellow at the Salk Institute , a position he held until 2010. After a three-year position as director of the National Institute of Neurological Disorders and Stroke , Fischbach became Vice President and Dean of Columbia University in 2001 . He has been with the Simons Foundation since 2006 , initially as director of their autism research, and since 2013 as chief scientist and fellow .

Gerald Fischbach examined the formation and maintenance of chemical synapses . He is considered a pioneer in the cell culture of nerve cells , on the basis of which he researched the physiology , morphology and biochemistry of synapses between nerve cells and between nerve cells and muscle cells. He was able to show that synaptic activity begins at the motor end plate as soon as the growth cone touches the muscle cell, but that the connection takes several weeks to fully develop. Further important work by Fischbach was concerned with the early appearance and regulation of glutamate and GABA receptors in the spinal cord and hippocampus , as well as with the temporal change of voltage-dependent calcium channels during the development of neurons. More recent work has shown the importance of neuregulin for the accumulation of acetylcholine receptors on the motor endplate. There are indications that the protein is important for the development of the brain and for the occurrence of certain neuropsychiatric disorders (see Neurobiological Concepts of Schizophrenia ). Fischbach has an h-index of 67.

In 1984 Fischbach was elected to the National Academy of Sciences , 1988 to the American Academy of Arts and Sciences , 1990 to the Institute of Medicine , 1991 to the American Association for the Advancement of Science and the European Academy of Sciences and Arts , 2003 to the American Philosophical Society . 1983/84 he was President of the Society for Neuroscience (SfN). In 1981 he received the W. Alden Spencer Award and in 1998 the Neuronal Plasticity Prize of the Ipsen Foundation. Fischbach holds honorary doctorates from Colgate University (2003), Hallym University (South Korea, 2008) and Washington University in St. Louis (2015).

Web links

Individual evidence

  1. ↑ Gerry Fischbach - Google Scholar Citations. In: scholar.google.de. Retrieved May 13, 2018 .
  2. ↑ Gerald Fischbach. In: nasonline.org. Retrieved May 13, 2018 .
  3. ↑ Book of Members 1780 – present, Chapter F. (PDF; 815 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 13, 2018 .
  4. ↑ Fischbach, Gerald D. In: aaas.org. February 9, 2018, accessed May 13, 2018 .
  5. ↑ Member History. In: search.amphilsoc.org. Retrieved May 13, 2018 .
  6. ^ Society for Neuroscience Presidents. In: sfn.org. Retrieved May 13, 2018 .
  7. ^ Neurosciences. (No longer available online.) In: fondation-ipsen.org. April 22, 2016, archived from the original on July 21, 2017 ; accessed on May 13, 2018 (English).
personal data
SURNAME Fischbach, Gerald D.
ALTERNATIVE NAMES Fischbach, Gerald; Fischbach, Gerry; Fischbach, Gerald David
BRIEF DESCRIPTION American neuroscientist
DATE OF BIRTH November 15, 1938
PLACE OF BIRTH New Rochelle , New York