Heinz Falk

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Heinz Falk (2008)

Heinz Falk (born April 29, 1939 in St. Pölten ) is an Austrian chemist , emeritus for organic chemistry at the Johannes Kepler University Linz and editor of the series " Progress in the Chemistry of Organic Natural Compounds ".

Falk's research focuses on the structural analysis, synthesis , stereochemistry and photochemistry of plant and animal light-sensitive dyes, such as B. Hypericin .

Life

Falk was born on April 29, 1939 in St. Pölten, attended elementary school in Statzendorf and then secondary school in Krems an der Donau . After moving to Vienna in 1953 , he graduated from the Higher Federal Training and Research Institute for the Chemical Industry in Rosensteingasse and then graduated from evening school in 1959 , where he also met his future wife, Rotraud Falk (née Strohbach).

Falk has been married to Rotraud Falk since 1966 and they have one son ( Alexander Falk , CEO of the software company Altova ).

Falk began his studies in 1959 chemistry at the University of Vienna and in 1966 graduated , with Karl Schlögl was his mentor. As a result, Falk spent 1971 as a postdoctoral fellow at ETH Zurich . After his return to Vienna, he obtained his habilitation in 1972 and thus the license to teach organic chemistry at the University of Vienna.

Career

1966-1979

From 1966 Falk worked as an assistant at the Institute for Organic Chemistry at the University of Vienna . In 1975 he was appointed associate professor for physical organic chemistry at the University of Vienna. In the summer of 1978 Falk was invited to speak at the Gordon Research Conference in Wolfeboro .

since 1979

In 1979 Falk accepted an appointment as full professor of organic chemistry at the Johannes Kepler University in Linz , where he set up the new institute for organic chemistry. From 1989 to 1991 he was dean of the technical and natural sciences faculty. In 2005, Falk was named third-place among the top 10 scientists in Upper Austria by the OÖ Nachrichten .

Falk's research focus is on the group of organic dyes derived from the phenanthro [1,10,9,8-opqra] perylene-7,14-dione chromophore , such as B. the natural dyes Hypericin , Stentorin , Fringelite, Gymnochrome and Blepharismin. In addition, Falk deals with the hemin-analogue Corrphycen derivatives (z. B. as potential blood substitutes and heme oxygenase blockers) and other natural compounds such as. B. the natural sun protection factor urocanic acid .

Falk has published his scientific research results in two books and more than 300 published articles in refereed journals.

Works

Books

  • Heinz Falk: Selected Exercise Examples on the Nomenclature of Organic Compounds . Springer-Verlag, Vienna, New York 1978, ISBN 0-387-81479-5 .
  • Heinz Falk: The Chemistry of Linear Oligopyrroles and Bile Pigments . Springer-Verlag, Vienna, New York 1989, ISBN 0-387-82112-0 .

Scientific publications (selection)

  • H. Falk and H. Marko, Reduction of α-Bilindione-10-Thiol-Adduct as a Model for the Reduction Step of the Biliverdin Reductase System. Monthly Chem. 122, 319 (1991)
  • U. Wagner, C. Kratky, H. Falk and H. Woess, Crystal Structure and Conformation of 10-Aryl-bilatrienes-abc. Monthly Chem. 122, 749 (1991)
  • H. Falk and W. Schmitzberger, On the Nature of "Soluble" Hypericin in Hypericum Species. Monthly Chem., 123, 731 (1992)
  • C. Etzlstorfer, H. Falk, N. Mueller, W. Schmitzberger and U. Wagner, Tautomerism and Stereochemistry of Hypericin: Force Field, NMR, and X-ray Crystallographic Investigations. Monthly Chem., 124, 751 (1993)
  • H. Falk, C. Kratky, N. Mueller, W. Schmitzberger and U. Wagner, Structure Determination of the Biliverdin Apomyoglobin Complex. Crystal Structure Analysis of Two Crystal Forms at 1.4 and 1.5 * Resolution. J. Mol. Biol., 247, 326 (1995)
  • H. Falk, From the Photosensitizer Hypericin to the Photoreceptor Stentorin - the Chemistry of the Phenanthroperylene Quinones. Angew. Chemistry Int. Ed., 38, 3134-3154 (1999)
  • RA Obermüller, K. Hohenthanner, and H. Falk, Towards Hypericin-Derived Potential Photdynamic Therapy Agents. Photochem. Photobiol., 74, 211-215 (2001)
  • J. Leonhartsberger and H. Falk, The Protonation and Deprotonation Equilibria of Hypericin Revisited. Mh. Chem., 133, 167-172 (2002)
  • M. Deak and H. Falk, On the Chemistry of the Resveratrol Diastereomers. Mh. Chem., 134, 883-888 (2003)
  • Beate Hager, Mario Alva-Astudillo, and Heinz Falk, A Hemin-Analogous Corrphycene Derivative: Suppression of Heme Oxygenase and Reconstitution with Apomyoglobin. Mh. Chem., 134, 1499-1507 (2003)
  • Klaus Wolkenstein, Jürgen H. Gross, Heinz Falk, and Heinz F. Schöler, Preservation of hypericin and related polycyclic quinone pigments in fossil crinoids. Proceedings of the Royal Society B, 273, 451-456 (2006)
  • Mario Waser and Heinz Falk, Towards Second Generation Hypericin Based Photosensitizers for Photodynamic Therapy. Curr. Org. Chem. 11: 547-558 (2007)
  • K. Wolkenstein, JH Gross, and H. Falk, Boron-containing Organic Pigments from a Jurassic Red Alga. Proc. Nat. Acad. Sci. 107: 19374-19378 (2010)
  • M. Waser and H. Falk, Progress in the Chemistry of Second Generation Hypericin Based Photosensitizers. Curr. Org. Chem. 15: 3894-3907 (2012)
  • I. Teasdale, M. Waser, S. Wilfert, H. Falk, O. Brüggemann, Photoreactive, Water-soluble Conjugates of Hypericin with Polyphosphazenes. Monthly Chem. 143: 355-360 (2012)
  • H. Falk: American Museum of Natural History New York. Leitfossil.de (2013) September 12, 2013
  • H. Falk: Friedrich Simony on the 200th birthday. Leitfossil.de (2013) November 2, 2013
  • H. Falk: The 50th Mineralientage Munich - a review. Fossils 31 (2014) 60–62.
  • H. Falk: Exhibition at the NHM Vienna: Gabonionta - multicellular organisms 2.1 billion years ago! Leitfossil.de (2014) March 17, 2014.
  • H. Falk: "Squid and Ammonite" exhibition in the Biology Center of the Upper Austrian State Museum in Linz. Leitfossil.de (2014) April 25, 2014.
  • WP Pfeiffer, SK Dey, DA Lightner, H. Falk: Homorubins and homoverdins. Monthly Chem./Chem. Monthly 145 (2014) 963-981.
  • K. Wolkenstein, H. Sun, C. Griesinger, H. Falk: Identification of organic pigments in macrofossils: analytical challenges and recent advances. Abstr. of 2014 The Geological Society of America Meeting, Vancouver, BC (10-22 Oct. 2014), paper No. 108-14.
  • H. Falk: Mammoth ice mummy from Siberia visits the Natural History Museum Vienna. Leitfossil.de (2015) January 2, 2015.
  • H. Falk: The 51st Mineralientage Munich - a review. Fossils 32 (2015) 59–61.
  • H. Falk: Chemofossils. Leitfossil.de (2015) March 3, 2015.
  • H. Falk, AD Kinghorn: Foreword. Progr. Chem Org. Nat. Prod. 100 (2015) v-vi.
  • K. Wolkenstein, H. Sun, C. Griesinger, H. Falk: Exceptional preservation of polyketide secondary metabolites in macrofossils. Abstr. 27th Intern. Meeting on Org.Geochem. Sept. 13-18, Prague, Cz, 226.
  • H. Falk: Paratethys stromatolites from Ritzing (Burgenland, Austria) as witnesses of a climate crisis in the Middle Miocene. Leitfossil.de (2015) October 14, 2015.
  • H. Falk: Natural History Museum Vienna: The new halls of prehistory. Leitfossil.de (2015) October 14, 2015.
  • K. Wolkenstein, H. Sun, C. Griesinger, H. Falk: Structure and Absolute Configuration of Jurassic Polyketide-Derived Spiroborate Pigments Obtained from Microgram Quantities. J. Amer. Chem. Soc. 137 (2015) 13460-13463.
  • H. Falk: The woodpecker knocks in the Biology Center Linz. Leitfossil.de (2016) January 20, 2016.
  • H. Falk: Where the Viennese mammoths grazed - scientific expeditions through today's Vienna. Leitfossil.de (2016) May 10, 2016
  • H. Falk: An ammonite monument on the Rossmoosalm. Leitfossil.de (2016) June 9, 2016.
  • H. Falk: Augensteine ​​- witnesses of the great upheavals in the Eastern Alps in the last 35 million years. Leitfossil.de (2016) August 13, 2016.
  • D. Kinghorn, H. Falk, S. Gibbons, J. Kobayashi: Phytocannabinoids - Unraveling the Complex Chemistry and Pharmacology of Cannabis sativa, Preface. Prog. Chem Org. Nat. Prod. 103 (2017) v-vi.
  • H. Falk, K. Wolkenstein: Natural Product Molecular Fossils. Prog. Chem Org. Nat. Prod. 104 (2017) 1-126.
  • K. Wolkenstein, H. Sun, C. Griesinger, H. Falk: Structure and Absolute Configuration of Jurassic Polyketide-Derived Spiroborate Pigments Obtained from Microgram Quantities. J. Amer. Chem. Soc. 137 (2015) 13460-13463. doi : 10.1021 / jacs.5b08191
  • D. Kinghorn, H. Falk, S. Gibbons, J. Kobayashi: Phytocannabinoids - Unraveling the Complex Chemistry and Pharmacology of Cannabis sativa, Preface. Prog. Chem Org. Nat. Prod. 103 (2017) v-vi.
  • H. Falk, K. Wolkenstein: Natural Product Molecular Fossils. Prog. Chem Org. Nat. Prod. 104 (2017) 1-126.

Patents

Awards

Web links

Individual evidence

  1. ^ Springer Vienna / New York, Progress in the Chemistry of Organic Natural Compounds
  2. ^ Hypericin group at the Institute for Organic Chemistry ( Memento from March 26, 2012 in the Internet Archive ).
  3. ↑ biographical data, publications and Academic pedigree of Heinz Falk in academictree.org, accessed on 4 February 2018th
  4. ↑ Upper Austria News: Best of Upper Austria Part 18: The brightest minds (PDF; 119 kB)
  5. ↑ a b ÖAW members detail: Heinz Falk. OeAW , accessed on August 8, 2017 .
  6. ↑ Johannes Kepler University - News vom Campus, Issue 22, March 2004
  7. ^ Society of Austrian Chemists, Hall of Fame
  8. ↑ Prize winners. Rudolf Trauner Foundation, accessed on August 8, 2017 .
  9. ↑ JKU Universität Aktuell, Silver Medal awarded ( Memento of the original from July 6, 2011 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.jku.at
personal data
SURNAME Falk, Heinz
BRIEF DESCRIPTION Austrian chemist
DATE OF BIRTH April 29, 1939
PLACE OF BIRTH St. Polten