Human coronavirus 229E

from Wikipedia, the free encyclopedia
Human coronavirus 229E
Systematics
Classification : Viruses
Area : Riboviria
Empire : Orthornavirae
Phylum : Pisuviricota
Class : Pisoniviricetes
Order : Nidovirals
Subordination : Cornidovirineae
Family : Coronaviridae
Subfamily : Orthocoronavirinae
Genre : Alphacoronavirus
Subgenus : Duvinacovirus
Type : Human coronavirus 229E
Taxonomic characteristics
Genome : (+) ssRNA linear
Cover : available
Scientific name
Human coronavirus 229E
Short name
HCoV-229E
Left

The human coronavirus 229E (HCoV-229E) is a coronavirus that can infect humans and bats . The virus has an envelope and, as genetic material, a strand of single-stranded RNA of positive polarity . The host cell becomes infected by binding to an APN receptor. With the human coronavirus OC43 (to Betacoronavirus 1 ), the human coronavirus NL63 and the human coronavirus HKU1 , the human coronavirus 229E is one of the viruses that can cause a common cold . The species belongs to the family Coronaviridae , the subfamily Orthocoronavirinae (formerly Coronavirinae ) and the subgenus Duvinacovirus .

The virus was first detected in 1965 by Dorothy Hamre at the University of Chicago . In rare cases, severe lower respiratory tract infections, including pneumonia and bronchiolitis , can also occur, particularly in infants, the elderly, and people with compromised immune systems. The virus is also found in bats, from which it is believed to have spread to humans.

Individual evidence

  1. a b c d ICTV: ICTV Taxonomy history: Severe acute respiratory syndrome-related coronavirus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
  2. Jump up ↑ Yvonne Lim, Yan Ng, James Tam, Ding Liu: Human Coronaviruses: A Review of Virus – Host Interactions . In: Diseases . tape 4 , no. 4 , July 25, 2016, ISSN  2079-9721 , p. 26 , doi : 10.3390 / diseases4030026 , PMID 28933406 , PMC 5456285 (free full text).
  3. Anthony R. Fehr, Stanley Perlman: Coronaviruses: An Overview of Their Replication and Pathogenesis . In: Coronaviruses . tape 1282 . Springer New York, New York, NY 2015, ISBN 978-1-4939-2437-0 , pp. 1–23 , doi : 10.1007 / 978-1-4939-2438-7_1 , PMID 25720466 , PMC 4369385 (free full text).
  4. SKP Lau, P. Lee, AKL Tsang, CCY Yip, H. Tse: Molecular Epidemiology of Human Coronavirus OC43 Reveals Evolution of Different Genotypes over Time and Recent Emergence of a Novel Genotype due to Natural Recombination . In: Journal of Virology . tape 85 , no. 21 , November 1, 2011, ISSN  0022-538X , p. 11325–11337 , doi : 10.1128 / JVI.05512-11 , PMID 21849456 , PMC 3194943 (free full text).
  5. ER Gaunt, A. Hardie, ECJ Claas, P. Simmonds, KE Templeton: Epidemiology and Clinical Presentations of the Four Human Coronaviruses 229E, HKU1, NL63, and OC43 Detected over 3 Years Using a Novel Multiplex Real-Time PCR Method . In: Journal of Clinical Microbiology . tape 48 , no. 8 , August 1, 2010, ISSN  0095-1137 , p. 2940-2947 , doi : 10.1128 / JCM.00636-10 , PMID 20554810 , PMC 2916580 (free full text).
  6. International Committee on Taxonomy of Viruses (ICTV). Retrieved March 21, 2020 .
  7. Patrick CY Woo, Yi Huang, Susanna KP Lau, Kwok-Yung Yuen: Coronavirus Genomics and Bioinformatics Analysis . In: Viruses . tape 2 , no. 8 , August 24, 2010, ISSN  1999-4915 , p. 1804-1820 , doi : 10.3390 / v2081803 , PMID 21994708 , PMC 3185738 (free full text).
  8. Alex Knapp: The secret history of the first coronavirus 229E , in Forbes from April 12, 2020
  9. Coronaviruses and acute respiratory syndromes -MERS and SARS
  10. David Cyranoski: Virology: Portrait of a Killer , online edition of the article in Spectrum of Science No. 8, August 2020, pp. 40–49