Human metapneumovirus
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The human metapneumovirus (HMPV, en. Human metapneumovirus ) was first isolated as a new member of the Paramyxoviridae family in 2001 and assigned to the then new virus family Pneumoviridae in 2016 . It is genetically and clinically very closely related to the more common respiratory syncytial virus .
The HMPV replicates in the respiratory tract and mainly affects infants and children. In this age group, it accounts for up to 15% of annual bronchiolitis cases . According to a six-year US study, it is the second most common cause of bronchiolitis in children.
Most children have developed antibodies to HMPV by the age of five , even without having a severe lower respiratory infection .
Host spectrum
In addition to humans, the virus has been shown to infect chimpanzees and gorillas . By 2011, infections in chimpanzees in Tai National Park in Ivory Coast and gorillas in Rwanda had become known.
literature
- BG van den Hoogen et al. : A newly discovered human pneumovirus isolated from young children with respiratory tract disease. In: Nature Medicine . 7 (6), 2001, pp. 719-724. PMID 11385510 , doi : 10.1038 / 89098
- JS Kahn: Epidemiology of human metapneumovirus. In: Clin Microbiol Rev. 19 (3), Jul 2006, pp. 546-557. PMID 16847085 , PMC 1539100 (free full text), doi : 10.1128 / CMR.00014-06 .
- C. Escobar, V. Luchsinger et al. : Genetic variability of human metapneumovirus isolated from chilean children, 2003-2004. In: J Med Virol. 81 (2), 2009, pp. 340-344. PMID 19107972 , doi : 10.1002 / jmv.21399 .
Web links
- Human metapneumovirus in the NCBI database
Individual evidence
- ↑ ICTV Master Species List 2018b.v2 . MSL # 34, March 2019
- ↑ a b ICTV: ICTV Taxonomy history: Akabane orthobunyavirus , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)
- ↑ KM Edwards, Y. Zhu, MR Griffin, GA Weinberg, CB Hall, PG Szilagyi, MA State, M. Iwane, MM Prill, JV Williams: Burden of Human Metapneumovirus Infection in Young Children. In: N Engl J Med. 368, 2013, pp. 633-643 doi: 10.1056 / NEJMoa1204630
- ^ BG van den Hoogen, JC de Jong, J. Groen, T. Kuiken, R. de Groot, RA Fouchier, AD Osterhaus: A newly discovered human pneumovirus isolated from young children with respiratory tract disease. In: Nat Med. 7 (6), June 2001, pp. 719-724.
- ↑ Nadja Podbregar: Coronavirus: Are great apes also endangered? , on: scinexx.de from March 30, 2020