Indolizine
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| General | |||||||||||||||||||
| Surname | Indolizine | ||||||||||||||||||
| other names |
Pyrrolo [1,2-a] pyridine |
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| Molecular formula | C 8 H 7 N | ||||||||||||||||||
| Brief description |
colorless solid |
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| properties | |||||||||||||||||||
| Molar mass | 117.15 g mol −1 | ||||||||||||||||||
| Physical state |
firmly |
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| Melting point |
75 ° C |
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| boiling point |
205 ° C |
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| solubility |
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||||||||
Indolizine is a chemical compound from the group of heteroaromatic bicyclic compounds having bridgehead - nitrogen atom.
Occurrence
Indolizine occurs naturally as the basic structure of many alkaloids ( e.g. rotundifoline , leurosine , eburnine , Catharanthus alkaloids ).
Extraction and presentation
Indolizine is formed when 2-methylpyridine is heated with α-bromoacetaldehyde and during the decarboxylation of indolizine-2-carboxylic acid , which is accessible from 2-methylpyridine and α-bromopyruvic acid.
properties
Indolizine is in the form of naphthalene- smelling, colorless flakes, which are easily soluble in organic solvents, and are soluble in warm dilute acids with gradual decomposition. It is steam volatile. The hydrochloric acid solution turns a spruce wood chip red, its solutions in benzene fluoresce strongly violet.
Individual evidence
- ↑ a b c Lexicon of Chemistry: Indolizin - Lexikon der Chemie , accessed on May 28, 2020
- ↑ a b c d David R. Lide: CRC Handbook of Chemistry and Physics A Ready-reference Book of Chemical and Physical Data . CRC Press, 1995, ISBN 978-0-8493-0595-5 , pp. 332 ( limited preview in Google Book search).
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Eberhard Breitmeier, Günther Jung: Organic chemistry . Basics, substance classes, reactions, concepts, molecular structure. 5th edition. Georg Thieme Verlag, Stuttgart 2005, ISBN 3-13-541505-8 , p. 698 ( limited preview in Google Book search).
