Irving B. Fritz

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Irving Bamdas Fritz (* 11. February 1927 in Rocky Mount , North Carolina ; † the thirtieth January 1996 in Grantchester , UK ) was an American metabolism - physiologist and endocrinologist .

Life

Irving started with 16 to study at the University of Richmond , Virginia, acquired 21 a degree in dentistry (Doctor of Dental Surgery) at the Medical College of Virginia and at age 24 in 1951, a Ph.D. in Physiology from the University of Chicago . The topic of the dissertation was The Relationship Between Adrenal Cortical Steroids and Neuro-humoral Effector Substances in the Hemodynamics of Adrenalectomized Animals Subjected to Stress . He then did his two years of military service. In 1954 he went to Copenhagen as a postdoctoral fellow with Einar Lundsgaard . He held the position of assistant director of the department of metabolism and endocrinology at Michael Reese Hospital in Chicago for two years before becoming professor of physiology at the University of Michigan in 1957 . In 1968 he moved to the Banting Best Institute at the University of Toronto as the successor to Charles Best . In 1991 he retired and headed a working group at the Institute of Animal Physiology and Genetics Research in Cambridge , United Kingdom , which he held until his death.

Fritz was married and had three sons. He died of cancer .

Act

At the beginning of his career, Fritz dealt with fat metabolism . He was able to explain the role of carnitine and the carnitine acyltransferase system in the metabolism of fatty acids . Fritz later turned to andrology and was able to make important contributions to the understanding of the function of the Sertoli cells , the follicle-stimulating hormone and the androgen-binding protein . Later work dealt with the cell-cell interaction (see communication (biology) ) in the testes and the role of plasminogen - activator , clusterin and the extracellular matrix in it. In the last years of his scientific career he dealt again with carnitine and its importance in the cell-cell interaction in the testes.

Awards (selection)

literature

Individual evidence

  1. ^ World Who's Who in Science: A Biographical Dictionary of Notable Scientists from Antiquity to the Present. 1968, page 613, ISBN 978-0-8379-1001-7
  2. Weekly Information from the Dean's Office, Faculty of Medicine, University of Toronto, February 19, 1996 at the University of Toronto (utoronto.ca); Retrieved March 24, 2013
  3. ^ A b c Medical College of Virginia Alumni Association of Scarab (Volume v.9: no.4 (1960: Nov.)) At ebooksread.com; Retrieved March 24, 2013
  4. Irving B. Fritz: Carnitine Deficiency. ( Memento of February 15, 2016 in the Internet Archive ) At: Canadians for Health Research (chrcrm.org); Retrieved March 24, 2013
  5. Irving B. Fritz at the University of Michigan (um2017.org); Retrieved March 24, 2013
  6. ^ Irving B. Fritz at the John Simon Guggenheim Memorial Foundation (gf.org); accessed on February 11, 2016
  7. Irving B. Fritz PhD at the Gairdner Foundation (gairdner.org); Retrieved March 24, 2013