Cashmere bee virus

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Cashmere bee virus
Systematics
Classification : Viruses
Area : Riboviria
Empire : Orthornavirae
Phylum : Pisuviricota
Class : Pisoniviricetes
Order : Picornavirales
Family : Dicistroviridae
Genre : Aparavirus
Type : Cashmere bee virus
Taxonomic characteristics
Genome : (+) ssRNA linear
Baltimore : Group 4
Symmetry : icosahedral
Cover : no
Scientific name
Kashmir bee virus
Short name
KBV
Left
NCBI  Taxonomy: 68876
NCBI  Reference: NC_004807
ICTV Taxon History: 201851916

The Kashmir Bee Virus (KBV, officially Kashmir Bee Virus ), also known as Kashmir Virus for short , is a virus that attacks various species of bees and is associated with the occurrence of bee deaths .

features

KBV is serologically very similar to the closely related acute paralysis virus (APV). Its genome sequence was published in 2004. The genome consists of single-stranded RNA in positive polarity with a length of 9506 nucleotides . It contains two open reading frames . The first and larger ORF is followed by a 608 nucleotide long non- transcribed region (NTR). It codes for a polyprotein that comprises three helicase domains, one 3C protease domain and eight RNA polymerase domains . The second ORF follows a relatively long intergenic sequence compared to the APV and codes for a structural polyprotein with two capsid protein domains . The 3 'end of the genome is polyadenylated .

Host range and symptoms

The Kashmir bee virus was first isolated from the eastern honey bee ( Apis cerana ) in 1974 , but also affects the western honey bee ( Apis mellifera ) and other hymenoptera such as various bumblebee species ( Bombus ) and the German wasp ( Vespula germanica ). In the species mentioned, the virus occurs in natural populations on different continents.

KBV can often be detected together with related viruses. Infection with KBV alone is usually symptom-free , but it can be fatal if other stress factors are added.

literature

  • JR de Miranda, M. Drebot, S. Tyler, M. Shen, CE Cameron, DB Stoltz, SM Camazine: Complete nucleotide sequence of Kashmir bee virus and comparison with acute bee paralysis virus . In: Journal of General Virology . tape 85 , no. 8 , 2004, p. 2263–2270 (English, full text ).

Individual evidence

  1. ↑ ICTV Master Species List 2018b.v2 . MSL # 34, March 2019
  2. ↑ a b c d ICTV: ICTV Taxonomy history: Enterovirus C , EC 51, Berlin, Germany, July 2019; Email ratification March 2020 (MSL # 35)