Lithium acetate

Structural formula
General
Surname	Lithium acetate
other names	Lithium ethanoate ( IUPAC )
Molecular formula	C 2 H 3 LiO 2
Brief description	white, odorless solid (dihydrate)
External identifiers / databases
CAS number 546-89-4 6108-17-4 (dihydrate) EC number 208-914-3 ECHA InfoCard 100.008.105 PubChem 3474584 Wikidata Q416969
properties
Molar mass	65,99 g · mol -1 102.02 g mol −1 (dihydrate)
Physical state	firmly
density	1.23 g cm −3 (anhydrate)
Melting point	280–285 ° C (anhydrate) 56–58 ° C (dihydrate)
solubility	good in water (408 g l −1 at 20 ° C, anhydrate) good in water (290 g l −1 at 20 ° C, dihydrate)
safety instructions
GHS labeling of hazardous substances Caution H and P phrases H: 319 P: 280-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Lithium acetate is the lithium salt of acetic acid with the empirical formula CH ₃ COOLi.

Extraction and presentation

Lithium acetate can be produced from lithium hydroxide and acetic acid by the salt formation reaction .

${\displaystyle \mathrm {LiOH+CH_{3}COOH\longrightarrow CH_{3}COOLi+H_{2}O} }$

The synthesis from lithium carbonate and acetic acid is also possible with the evolution of carbon dioxide .

${\displaystyle \mathrm {Li_{2}CO_{3}+2\ CH_{3}COOH\longrightarrow 2\ CH_{3}COOLi+CO_{2}\uparrow +\ H_{2}O} }$

properties

Lithium acetate is usually commercially available as a white dihydrate with the formula CH ₃ COOLi · 2 H ₂ O. The dihydrate crystallizes in the orthorhombic crystal system in the space group Cmm 2 (space group no. 35) with the lattice constants a = 686  pm , b = 1149 pm and c = 659 pm. The anhydrate crystallizes in the triclinic crystal system in the space group P 1 (No. 2) with the lattice constants a = 929 pm, b = 1213 pm and c = 676 pm as well as α = 101 °, β = 100 ° and γ = 105 °.

use

Lithium acetate is used as a buffer substance in the gel electrophoresis of DNA and RNA , in the transformation of yeast cells by the lithium acetate method and in lithium therapy . It is also used as a catalyst in polyester production , as a corrosion inhibitor in polyphenyl sulfide resins and as a catalyst in the production of alkyd resins and acrylic polymers.

Individual evidence

1. ↑ ^{a b c} data sheet Lithium acetate dihydrate, 98% from Acros, accessed on August 4, 2019.
2. ↑ ^{a b} C. Saunderson, RB Ferguson: Crystal data for anhydrous lithium acetate. In: Acta Cryst. (1961). 14, 321, doi: 10.1107 / S0365110X61001017 .
3. ↑ ^{a b c d} data sheet Lithium acetate, 99 +%, for analysis, anhydrous at Acros, accessed on August 4, 2019.
4. ↑ ^{a b} Ulrich Wietelmann, Richard J. Bauer: lithium and lithium compounds. In: Ullmann's Encyclopedia of Industrial Chemistry. Wiley-VCH, Weinheim 2005, doi : 10.1002 / 14356007.a15_393 .
5. ↑ Data sheet Lithium acetate dihydrate from Sigma-Aldrich , accessed on July 7, 2019 ( PDF ).
6. ↑ V. Amirthalingam, VM Padmanabhan: The crystal structure of lithium acetate dihydrate CH ₃ COOLi.2H ₂ O. In: Acta Cryst . Volume 11, 1958, p. 896, doi: 10.1107 / S0365110X58002541 .
7. ↑ Michael Wink (Ed.): Molecular Biotechnology: Concepts, Methods and Applications . 2nd Edition. Wiley-VCH, Weinheim 2011, ISBN 978-3-527-32655-6 , pp. 173 ( limited preview in Google Book search).
8. ↑ FMC Lithium: lithium acetate dihydrate (PDF; 272 kB)