Mariano Barbacid

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Mariano Barbacid Montalbán (born October 4, 1949 in Madrid ) is a Spanish biologist and cancer researcher.

Barbacid graduated from Complutense University in Madrid with degrees in Chemistry and 1971 in Biochemistry, and in 1974 Ph.D. from Complutense University and the Consejo Superior de Investigaciones Científicas (CSIC). , also in biochemistry. As a postdoctoral fellow he worked at the National Cancer Institute (NCI) in Bethesda , Maryland , where in 1978 Stuart A. Aaronson gave him a position as research group leader. In 1984 he became head of the department for research into the development of cancer of the NCI in Frederick , Maryland. In 1988 Barbacid moved to the Department of Molecular Biology of the Bristol-Myers Squibb Pharm. Research Institute (BMSPRI) in Princeton , New Jersey , as Managing Director , and in 1992 he became Vice President of Molecular Biology and Oncological Drug Discovery of the BMSPRI. From 1998 to 2011 he was the founding director of the Centro Nacional de Investigaciones Oncologicas in Madrid, the Spanish national cancer research institute. Since 2011 he has been concentrating on his own research there.

Mariano Barbacid is mostly for his contributions to the discovery of the H-RAS known of the first discovered proto- oncogene , and the first identification of a mutation of the H-RAS with, cancer is associated. He could also make important contributions to the study of neurotrophins accomplish: He discovered the Trk - family of genes for tyrosine kinase receptors and showed that these convey the signal transmission of the neurotrophins. He contributed to the clarification of the importance of cyclin-dependent kinases for the cell cycle and cell proliferation . More recent work deals with new animal models for cancer and the identification of target molecules for potential cancer drugs. Barbacid has (as of November 2017) an h-index of 112.

Barbacid has received numerous awards, including the Dr. Josef Steiner Cancer Research Prize , the Neuronal Plasticity Prize of the Fondation Ipsen in 1994 , an honorary doctorate from the Universidad Internacional Menéndez Pelayo in 1995 , the Charles Rodolphe Brupbacher Prize for Cancer Research in 2005 and an honorary doctorate from the Universidad de Cantabria in 2011 . In 1995 he was elected to the European Molecular Biology Organization , 2004 to the Academia Europaea , 2012 to the National Academy of Sciences .

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Individual evidence

  1. ↑ Curriculum vitae (PDF, 138 kB) at the Institute for Biochemistry II at the Johann Wolfgang Goethe University Frankfurt am Main (biochem2.com); accessed on November 24, 2017.
  2. ^ Mariano Barbacid - Google Scholar Citations. In: scholar.google.com. Retrieved November 24, 2017 .
  3. ↑ Dr. Josef Steiner Cancer Research Prize 1988 ( Memento from July 14, 2016 in the Internet Archive )
  4. ^ Neurosciences. (No longer available online.) In: fondation-ipsen.org. April 22, 2016, archived from the original on July 21, 2017 ; accessed on November 24, 2017 (English).
  5. ^ Brupbacher Prize. In: brupbacher-foundation.org. Retrieved April 29, 2019 .
  6. ↑ Mariano Barbacid. In: people.embo.org. Retrieved November 24, 2017 .
  7. ↑ Ilire Hasani, Robert Hoffmann: Academy of Europe: Barbacid Mariano. In: ae-info.org. December 19, 2014, accessed November 24, 2017 .
personal data
SURNAME Barbacid, Mariano
ALTERNATIVE NAMES Barbacid Montalbán, Mariano (full name)
BRIEF DESCRIPTION Spanish biologist and cancer researcher
DATE OF BIRTH October 4, 1949
PLACE OF BIRTH Madrid