Methyltestosterone

Structural formula
General
Non-proprietary name	Methyltestosterone
other names	17 α- methyltestosterone; Mesteron; 17 α -methyl-4-androstene-17 β -ol-3-one;
Molecular formula	C 20 H 30 O 2
Brief description	light yellow powder
External identifiers / databases
EC number	200-366-3
ECHA InfoCard	100,000,333
PubChem	6010
ChemSpider	5788
DrugBank	DB06710
Wikidata	Q421768
Drug information
ATC code	G03 BA02
properties
Molar mass	302.45 g mol −1
Physical state	firmly
Melting point	162-168 ° C
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances danger
H and P phrases	H: 350-361
	P: 201-281-308 + 313
Toxicological data	2500 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Methyltestosterone is a synthetically produced drug from the group of anabolic steroids ( xenoandrogen ) and is a derivative ( derivative ) of the physiologically occurring sex hormone testosterone .

The 17 α - alkylated steroid is one of the first orally ingestible steroids and, like oxymetholone and metandienone, has a strong anabolic and androgenic effect. After ingestion, it is able to convert into 17-methyl estradiol , the rate of aromatization being around 13-16 times as high as that of testosterone. 17-methylestradiol has a particularly strong estrogenic effect.

The side effects worth mentioning include: hair loss , severe acne , severe stress on the liver , severe weight gain (usually 90% of this is water and fat). Longer use increases the risk of gynecomastia . Another serious side effect is the strong effect on the psyche (depression, nervousness, mood swings, changes in libido, increased aggressiveness and violence).

Medically, methyltestosterone in injectable form is indicated for the treatment of underactive gonads in men ( hypogonadism ), but is no longer of great medical importance due to severe side effects.

Abuse in Sports

Methyltestosterone is considered a doping agent and is used particularly by boxers, strength athletes and wrestlers. The effect sets in quickly.

Individual evidence

↑ ^a ^b ^c ^d ^e data sheet 17α-Methyltestosterone from Sigma-Aldrich , accessed on June 18, 2011 ( PDF ).
↑ ^a ^b Technical information Sustanon 100 mg / ml. NV Organon, May 2011.
↑ D. Sinner: The Black Book - Anabolic Steroids. BMS-Verlag, Gronau 2007, ISBN 978-3-00-020944-4 , pp. 333-334.

[Sigma-1] ↑ ^a ^b ^c ^d ^e data sheet 17α-Methyltestosterone from Sigma-Aldrich , accessed on June 18, 2011 ( PDF ).

[FI-2] Technical information Sustanon 100 mg / ml. NV Organon, May 2011.

[3] D. Sinner: The Black Book - Anabolic Steroids. BMS-Verlag, Gronau 2007, ISBN 978-3-00-020944-4 , pp. 333-334.