Ofurac
Structural formula | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Structural formula without stereochemistry | ||||||||||||||||
General | ||||||||||||||||
Surname | Ofurac | |||||||||||||||
other names |
|
|||||||||||||||
Molecular formula | C 14 H 16 ClNO 3 | |||||||||||||||
Brief description |
colorless crystals |
|||||||||||||||
External identifiers / databases | ||||||||||||||||
|
||||||||||||||||
properties | ||||||||||||||||
Molar mass | 281.73 g mol −1 | |||||||||||||||
Physical state |
firmly |
|||||||||||||||
Melting point |
145-146 ° C |
|||||||||||||||
solubility |
very heavy in water (140 mg l −1 at 21 ° C) |
|||||||||||||||
safety instructions | ||||||||||||||||
|
||||||||||||||||
Toxicological data | ||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Ofurac is a chemical compound from the anilide group and a systemic fungicide from the phenylamide family .
history
Ofurac was developed by Chevron and launched in 1992. Bayer CropScience holds the rights today .
Extraction and presentation
Ofurac can be obtained by reacting chloroacetic acid chloride with 2,6-dimethylaniline and 3-chloro-γ-butyrolactone .
use
Ofurac has a systemic, protective and curative effect. The active ingredient inhibits the synthesis of ribosomal RNA . It is often used along with other fungicides to control oomycetes .
Admission
No plant protection products containing this active ingredient are permitted in the EU or Switzerland .
Individual evidence
- ↑ a b c d e f Entry on Ofurac. In: Römpp Online . Georg Thieme Verlag, accessed on November 17, 2014.
- ↑ a b Ofurace data sheet at Sigma-Aldrich , accessed on May 20, 2017 ( PDF ).
- ↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 45 ( limited preview in Google Book search).
- ↑ David J. Fisher, Ann L. Hayes: Mode of action of the systemic fungicides furalaxyl, metalaxyl and ofurace . In: Pesticide Science . tape 13 , no. 3 , June 1982, pp. 330–339 , doi : 10.1002 / ps.2780130316 ( PDF ).
- ^ Directorate-General for Health and Food Safety of the European Commission: Entry on Ofurace in the EU pesticide database ; Entry in the national registers of plant protection products in Switzerland , Austria and Germany ; accessed on March 26, 2016.