Ponceau 6R
Structural formula | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
General | ||||||||||||||||
Surname | Ponceau 6R | |||||||||||||||
other names |
|
|||||||||||||||
Molecular formula | C 20 H 12 N 2 Na 2 O 7 S 2 | |||||||||||||||
Brief description |
red solid |
|||||||||||||||
External identifiers / databases | ||||||||||||||||
|
||||||||||||||||
properties | ||||||||||||||||
Molar mass | 502.43 g mol −1 | |||||||||||||||
Physical state |
firmly |
|||||||||||||||
Melting point |
> 300 ° C |
|||||||||||||||
safety instructions | ||||||||||||||||
|
||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Ponceau 6R (also Crystal scarlet , in German 'Kristallscharlachrot') is a red azo dye .
properties
Ponceau 6R is water-soluble and, to a lesser extent, also soluble in ethanol . Ponceau 6R is used as a food additive E 126 but is not approved in the EU. In addition, Ponceau 6R, mostly as the sodium salt, is used in histology to stain fibrin in the course of MSB trichrome staining (together with Martin's yellow and water blue ). Alternatively, amaranth is used in trichrome staining . In animal experiments , Ponceau 6R leads in high doses to hemolytic anemia via the formation of hemiglobin .
Individual evidence
- ↑ a b c d Datasheet Ponceau 6R, analytical standard at Sigma-Aldrich , accessed on November 24, 2013 ( PDF ).
- ^ A b E. V. Hansen, G. Würtzen, D. Søndergaard, P. Skydsgaard: A short term peroral study of the food color, Ponceau 6R in pigs. In: Toxicology . Volume 10, Number 4, August 1978, pp. 363-368, PMID 694944 .
- ↑ N. Yoshioka, K. Ichihashi: Determination of 40 synthetic food colors in drinks and candies by high-performance liquid chromatography using a short column with photodiode array detection. In: Talanta . Volume 74, number 5, February 2008, pp. 1408-1413, doi: 10.1016 / j.talanta.2007.09.015 . PMID 18371797 .
- ↑ List of EU-approved food additives ( Memento of the original from December 3, 2013 in the Internet Archive ) Info: The archive link has been inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. . Retrieved November 24, 2013.
- ↑ G. Würtzen, JC Larsen, F. Tarding: Hemiglobin formation in vitro induced by azo dyes and their metabolites. In: Archives of Toxicology . Supplement. Number 1, 1978, pp. 309-311, PMID 277121 .