Propetamphos

Structural formula
General
Surname	Propetamphos
other names	O - (2- (Isopropoxycarbonyl) -1-methyl) vinyl- O -methyl- (ethylamido) thiophosphate; Safrotine; Seraphos (?);
Molecular formula	C 10 H 20 NO 4 PS
Brief description	yellowish, oily liquid
External identifiers / databases
EC number	250-517-2
ECHA InfoCard	100.045.910
PubChem	5372405
Wikidata	Q18629963
properties
Molar mass	281.31 g mol −1
Physical state	liquid
density	1.1294 g cm −3
boiling point	87-89 ° C (0.007 hPa )
solubility	very heavy in water (0.11 g l −1 at 24 ° C)
Refractive index	1.495
safety instructions
H and P phrases	H: 301-410
	P: 273-301 + 310-501
Toxicological data	62.4 mg kg −1 ( LD 50 , rat , oral ) ; 564 mg kg −1 ( LD 50 , rat , transdermal ) ;
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Propetamphos is a chemical compound from the group of thiophosphoric acid esters . The compound has been used as an insecticide against hygiene pests.

Extraction and presentation

Propetamphos can be prepared from isopropyl acetoacetate and thiophosphoryl trichloride . Their product reacts with methanol and ethylamine to form the end product.

↑ ^a ^b Crop Protection Handbook 2014 . 100th edition. MeisterPro, Willoughby, Ohio 2014, pp. 491 .
↑ ^a ^b ^c ^d ^e ^f Entry on Propetamphos in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ Metabolic Pathways of Agrochemicals, p. 462.
↑ Entry on trans-isopropyl-3 - [[(ethylamino) methoxyfosfinothioyl] oxy] crotonate Template: Linktext-Check / Escaped in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Thomas A. Unger: Pesticide Synthesis Handbook . William Andrew, 1996, ISBN 0-8155-1853-6 , pp. 381 ( limited preview in Google Book Search).