Ralph A. Bradshaw

Ralph Alden Bradshaw (born February 14, 1941 in Dorchester , Massachusetts ) is an American biochemist .

Bradshaw earned a bachelor's degree in chemistry from Colby College in 1962 and a Ph.D. from Robert L. Hill at Duke University in 1966. in biochemistry . As a postdoctoral fellow he worked with Frank Gurd at Indiana University Bloomington and with Hans Neurath at the University of Washington ( Seattle ).

In 1969 Bradshaw became Assistant Professor of Biochemistry at Washington University School of Medicine ( St. Louis ) , Associate Professor in 1972 , and Full Professor in 1974. In 1982 he moved to the medical faculty of the University of California, Irvine (UCI) as professor of biochemistry , where he was also chair until 1993 . In 1997 he switched to a professorship for physiology and biophysics and one for anatomy and neurobiology at the same university. In 2006 he was at UCI professor emeritus . Since 2006 he has been Professor of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF).

Bradshaw spent research stays at the University of Melbourne (Australia) in 1977/1978 , at the Max Planck Institute for Biochemistry (Germany) in 1992/1993 and at Cambridge University (United Kingdom) in 2004/2005 .

Bradshaw did a lot to clarify the structure and function of various proteins , in particular dehydrogenases and growth factors such as nerve growth factor (NGF, together with Rita Levi-Montalcini , who received the 1986 Nobel Prize in Physiology or Medicine ), epidermal growth factor (EGF) and fibroblast growth factor 2 (b-FGF). He studies signal transduction in eukaryotes and the co- and post-translational modification of the N -termini of proteins.

In 1976 he received the Passano Young Scientist Award from the Passano Foundation . He was founding president of the Protein Society in 1986/87 and president of the Federation of American Societies for Experimental Biology (FASEB) in 1995/96 . He was an editor of the Journal of Biological Chemistry .

Sources and References

literature

• Nicole Kresge, Robert D. Simoni, Robert L. Hill: Proving the Hormonal Nature of Nerve Growth Factor: the Work of Ralph A. Bradshaw. In: Journal of Biological Chemistry 283, e13. 2008.

Web links

• Ralph Bradshaw at the University of California, San Francisco (ucsf.edu)
• Ralph A. Bradshaw at the University of California, Irvine (uci.edu)

Individual evidence

1. ^ Recipients of the Passano Laureate and Physician Scientist Awards. In: passanofoundation.org. Retrieved May 9, 2019 . 
2. ↑ Ralph A. Bradshaw, PhD - FASEB Board of Directors (PDF, 251 kB); Retrieved November 26, 2017.